PubMed:32219357 JSONTXT 32 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-74 Sentence denotes Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19).
TextSentencer_T2 75-86 Sentence denotes Importance:
TextSentencer_T3 87-177 Sentence denotes Virus infection has been widely described as one of the most common causes of myocarditis.
TextSentencer_T4 178-323 Sentence denotes However, less is known about the cardiac involvement as a complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
TextSentencer_T5 324-334 Sentence denotes Objective:
TextSentencer_T6 335-605 Sentence denotes To describe the presentation of acute myocardial inflammation in a patient with coronavirus disease 2019 (COVID-19) who recovered from the influenzalike syndrome and developed fatigue and signs and symptoms of heart failure a week after upper respiratory tract symptoms.
TextSentencer_T7 606-639 Sentence denotes Design, Setting, and Participant:
TextSentencer_T8 640-957 Sentence denotes This case report describes an otherwise healthy 53-year-old woman who tested positive for COVID-19 and was admitted to the cardiac care unit in March 2020 for acute myopericarditis with systolic dysfunction, confirmed on cardiac magnetic resonance imaging, the week after onset of fever and dry cough due to COVID-19.
TextSentencer_T9 958-1038 Sentence denotes The patient did not show any respiratory involvement during the clinical course.
TextSentencer_T10 1039-1048 Sentence denotes Exposure:
TextSentencer_T11 1049-1083 Sentence denotes Cardiac involvement with COVID-19.
TextSentencer_T12 1084-1111 Sentence denotes Main Outcomes and Measures:
TextSentencer_T13 1112-1400 Sentence denotes Detection of cardiac involvement with an increase in levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) and high-sensitivity troponin T, echocardiography changes, and diffuse biventricular myocardial edema and late gadolinium enhancement on cardiac magnetic resonance imaging.
TextSentencer_T14 1401-1409 Sentence denotes Results:
TextSentencer_T15 1410-1513 Sentence denotes An otherwise healthy 53-year-old white woman presented to the emergency department with severe fatigue.
TextSentencer_T16 1514-1564 Sentence denotes She described fever and dry cough the week before.
TextSentencer_T17 1565-1724 Sentence denotes She was afebrile but hypotensive; electrocardiography showed diffuse ST elevation, and elevated high-sensitivity troponin T and NT-proBNP levels were detected.
TextSentencer_T18 1725-1767 Sentence denotes Findings on chest radiography were normal.
TextSentencer_T19 1768-1846 Sentence denotes There was no evidence of obstructive coronary disease on coronary angiography.
TextSentencer_T20 1847-2021 Sentence denotes Based on the COVID-19 outbreak, a nasopharyngeal swab was performed, with a positive result for SARS-CoV-2 on real-time reverse transcriptase-polymerase chain reaction assay.
TextSentencer_T21 2022-2248 Sentence denotes Cardiac magnetic resonance imaging showed increased wall thickness with diffuse biventricular hypokinesis, especially in the apical segments, and severe left ventricular dysfunction (left ventricular ejection fraction of 35%).
TextSentencer_T22 2249-2457 Sentence denotes Short tau inversion recovery and T2-mapping sequences showed marked biventricular myocardial interstitial edema, and there was also diffuse late gadolinium enhancement involving the entire biventricular wall.
TextSentencer_T23 2458-2563 Sentence denotes There was a circumferential pericardial effusion that was most notable around the right cardiac chambers.
TextSentencer_T24 2564-2626 Sentence denotes These findings were all consistent with acute myopericarditis.
TextSentencer_T25 2627-2820 Sentence denotes She was treated with dobutamine, antiviral drugs (lopinavir/ritonavir), steroids, chloroquine, and medical treatment for heart failure, with progressive clinical and instrumental stabilization.
TextSentencer_T26 2821-2847 Sentence denotes Conclusions and Relevance:
TextSentencer_T27 2848-2991 Sentence denotes This case highlights cardiac involvement as a complication associated with COVID-19, even without symptoms and signs of interstitial pneumonia.