LitCovid-sentences-v1  

PubMed:32172546 JSONTXT 38 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-80 Sentence denotes [A pathological report of three COVID-19 cases by minimally invasive autopsies].
TextSentencer_T2 81-91 Sentence denotes Objective:
TextSentencer_T3 92-277 Sentence denotes To investigate the pathological characteristics and the clinical significance of novel coronavirus (2019-nCoV)-infected pneumonia (termed by WHO as corona virus disease 2019, COVID-19).
TextSentencer_T4 278-286 Sentence denotes Methods:
TextSentencer_T5 287-506 Sentence denotes Minimally invasive autopsies from lung, heart, kidney, spleen, bone marrow, liver, pancreas, stomach, intestine, thyroid and skin were performed on three patients died of novel coronavirus pneumonia in Chongqing, China.
TextSentencer_T6 507-656 Sentence denotes Hematoxylin and eosin staining (HE) and histochemical staining were performed to investigate the pathological changes of indicated organs or tissues.
TextSentencer_T7 657-793 Sentence denotes Immunohistochemical staining was conducted to evaluate the infiltration of immune cells as well as the expression of 2019-nCoV proteins.
TextSentencer_T8 794-855 Sentence denotes Real time PCR was carried out to detect the RNA of 2019-nCoV.
TextSentencer_T9 856-864 Sentence denotes Results:
TextSentencer_T10 865-971 Sentence denotes Various damages were observed in the alveolar structure, with minor serous exudation and fibrin exudation.
TextSentencer_T11 972-1028 Sentence denotes Hyaline membrane formation was observed in some alveoli.
TextSentencer_T12 1029-1108 Sentence denotes The infiltrated immune cells in alveoli were majorly macrophages and monocytes.
TextSentencer_T13 1109-1214 Sentence denotes Moderate multinucleated giant cells, minimal lymphocytes, eosinophils and neutrophils were also observed.
TextSentencer_T14 1215-1273 Sentence denotes Most of infiltrated lymphocytes were CD4-positive T cells.
TextSentencer_T15 1274-1395 Sentence denotes Significant proliferation of type II alveolar epithelia and focal desquamation of alveolar epithelia were also indicated.
TextSentencer_T16 1396-1526 Sentence denotes The blood vessels of alveolar septum were congested, edematous and widened, with modest infiltration of monocytes and lymphocytes.
TextSentencer_T17 1527-1584 Sentence denotes Hyaline thrombi were found in a minority of microvessels.
TextSentencer_T18 1585-1719 Sentence denotes Focal hemorrhage in lung tissue, organization of exudates in some alveolar cavities, and pulmonary interstitial fibrosiswere observed.
TextSentencer_T19 1720-1768 Sentence denotes Part of the bronchial epithelia were exfoliated.
TextSentencer_T20 1769-1893 Sentence denotes Coronavirus particles in bronchial mucosal epithelia and type II alveolar epithelia were observed under electron microscope.
TextSentencer_T21 1894-2018 Sentence denotes Immunohistochemical staining showed that part of the alveolar epithelia and macrophages were positive for 2019-nCoV antigen.
TextSentencer_T22 2019-2097 Sentence denotes Real time PCR analyses identified positive signals for 2019-nCoV nucleic acid.
TextSentencer_T23 2098-2186 Sentence denotes Decreased numbers of lymphocyte, cell degeneration and necrosis were observed in spleen.
TextSentencer_T24 2187-2456 Sentence denotes Furthermore, degeneration and necrosis of parenchymal cells, formation of hyaline thrombus in small vessels, and pathological changes of chronic diseases were observed in other organs and tissues, while no evidence of coronavirus infection was observed in these organs.
TextSentencer_T25 2457-2708 Sentence denotes Conclusion: s The lungs from novel coronavirus pneumonia patients manifest significant pathological lesions, including the alveolar exudative inflammation and interstitial inflammation, alveolar epithelium proliferation and hyaline membrane formation.
TextSentencer_T26 2709-2853 Sentence denotes While the 2019-nCoV is mainly distributed in lung, the infection also involves in the damages of heart, vessels, liver, kidney and other organs.
TextSentencer_T27 2854-2961 Sentence denotes Further studies are warranted to investigate the mechanism underlying pathological changes of this disease.