LitCovid-sentences-v1  

PubMed:32118640 JSONTXT 17 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-114 Sentence denotes Analysis of factors associated with disease outcomes in hospitalized patients with 2019 novel coronavirus disease.
TextSentencer_T2 115-126 Sentence denotes BACKGROUND:
TextSentencer_T3 127-264 Sentence denotes Since early December 2019, the 2019 novel coronavirus disease (COVID-19) has caused pneumonia epidemic in Wuhan, Hubei province of China.
TextSentencer_T4 265-368 Sentence denotes This study aims to investigate the factors affecting the progression of pneumonia in COVID-19 patients.
TextSentencer_T5 369-493 Sentence denotes Associated results will be used to evaluate the prognosis and to find the optimal treatment regimens for COVID-19 pneumonia.
TextSentencer_T6 494-502 Sentence denotes METHODS:
TextSentencer_T7 503-605 Sentence denotes Patients tested positive for the COVID-19 based on nucleic acid detection were included in this study.
TextSentencer_T8 606-710 Sentence denotes Patients were admitted to 3 tertiary hospitals in Wuhan between December 30, 2019, and January 15, 2020.
TextSentencer_T9 711-846 Sentence denotes Individual data, laboratory indices, imaging characteristics, and clinical data were collected, and statistical analysis was performed.
TextSentencer_T10 847-970 Sentence denotes Based on clinical typing results, the patients were divided into a progression group or an improvement/stabilization group.
TextSentencer_T11 971-1062 Sentence denotes Continuous variables were analyzed using independent samples t-test or Mann-Whitney U test.
TextSentencer_T12 1063-1143 Sentence denotes Categorical variables were analyzed using Chi-squared test or Fisher exact test.
TextSentencer_T13 1144-1239 Sentence denotes Logistic regression analysis was performed to explore the risk factors for disease progression.
TextSentencer_T14 1240-1248 Sentence denotes RESULTS:
TextSentencer_T15 1249-1363 Sentence denotes Seventy-eight patients with COVID-19-induced pneumonia met the inclusion criteria and were included in this study.
TextSentencer_T16 1364-1518 Sentence denotes Efficacy evaluation at 2 weeks after hospitalization indicated that 11 patients (14.1%) had deteriorated, and 67 patients (85.9%) had improved/stabilized.
TextSentencer_T17 1519-1698 Sentence denotes The patients in the progression group were significantly older than those in the disease improvement/stabilization group (66 [51, 70] vs. 37 [32, 41] years, U = 4.932, P = 0.001).
TextSentencer_T18 1699-1877 Sentence denotes The progression group had a significantly higher proportion of patients with a history of smoking than the improvement/stabilization group (27.3% vs. 3.0%, χ = 9.291, P = 0.018).
TextSentencer_T19 1878-2152 Sentence denotes For all the 78 patients, fever was the most common initial symptom, and the maximum body temperature at admission was significantly higher in the progression group than in the improvement/stabilization group (38.2 [37.8, 38.6] vs. 37.5 [37.0, 38.4]°C, U = 2.057, P = 0.027).
TextSentencer_T20 2153-2435 Sentence denotes Moreover, the proportion of patients with respiratory failure (54.5% vs. 20.9%, χ = 5.611, P = 0.028) and respiratory rate (34 [18, 48] vs. 24 [16, 60] breaths/min, U = 4.030, P = 0.004) were significantly higher in the progression group than in the improvement/stabilization group.
TextSentencer_T21 2436-2623 Sentence denotes C-reactive protein was significantly elevated in the progression group compared to the improvement/stabilization group (38.9 [14.3, 64.8] vs. 10.6 [1.9, 33.1] mg/L, U = 1.315, P = 0.024).
TextSentencer_T22 2624-2783 Sentence denotes Albumin was significantly lower in the progression group than in the improvement/stabilization group (36.62 ± 6.60 vs. 41.27 ± 4.55 g/L, U = 2.843, P = 0.006).
TextSentencer_T23 2784-2944 Sentence denotes Patients in the progression group were more likely to receive high-level respiratory support than in the improvement/stabilization group (χ = 16.01, P = 0.001).
TextSentencer_T24 2945-3049 Sentence denotes Multivariate logistic analysis indicated that age (odds ratio [OR], 8.546; 95% confidence interval [CI]:
TextSentencer_T25 3050-3115 Sentence denotes 1.628-44.864; P = 0.011), history of smoking (OR, 14.285; 95% CI:
TextSentencer_T26 3116-3199 Sentence denotes 1.577-25.000; P = 0.018), maximum body temperature at admission (OR, 8.999; 95% CI:
TextSentencer_T27 3200-3265 Sentence denotes 1.036-78.147, P = 0.046), respiratory failure (OR, 8.772, 95% CI:
TextSentencer_T28 3266-3319 Sentence denotes 1.942-40.000; P = 0.016), albumin (OR, 7.353, 95% CI:
TextSentencer_T29 3320-3389 Sentence denotes 1.098-50.000; P = 0.003), and C-reactive protein (OR, 10.530; 95% CI:
TextSentencer_T30 3390-3457 Sentence denotes 1.224-34.701, P = 0.028) were risk factors for disease progression.
TextSentencer_T31 3458-3470 Sentence denotes CONCLUSIONS:
TextSentencer_T32 3471-3677 Sentence denotes Several factors that led to the progression of COVID-19 pneumonia were identified, including age, history of smoking, maximum body temperature on admission, respiratory failure, albumin, C-reactive protein.
TextSentencer_T33 3678-3771 Sentence denotes These results can be used to further enhance the ability of management of COVID-19 pneumonia.