Id |
Subject |
Object |
Predicate |
Lexical cue |
TextSentencer_T1 |
0-95 |
Sentence |
denotes |
[Study on assessing early epidemiological parameters of coronavirus disease epidemic in China]. |
TextSentencer_T2 |
96-106 |
Sentence |
denotes |
Objective: |
TextSentencer_T3 |
107-368 |
Sentence |
denotes |
To study the early dynamics of the epidemic of coronavirus disease (COVID-19) in China from 15 to 31 January, 2020, and estimate the corresponding epidemiological parameters (incubation period, generation interval and basic reproduction number) of the epidemic. |
TextSentencer_T4 |
369-377 |
Sentence |
denotes |
Methods: |
TextSentencer_T5 |
378-580 |
Sentence |
denotes |
By means of Weibull, Gamma and Lognormal distributions methods, we estimated the probability distribution of the incubation period and generation interval data obtained from the reported COVID-19 cases. |
TextSentencer_T6 |
581-656 |
Sentence |
denotes |
Moreover, the AIC criterion was used to determine the optimal distribution. |
TextSentencer_T7 |
657-923 |
Sentence |
denotes |
Considering the epidemic is ongoing, the exponential growth model was used to fit the incidence data of COVID-19 from 10 to 31 January, 2020, and exponential growth method, maximum likelihood method and SEIR model were used to estimate the basic reproduction number. |
TextSentencer_T8 |
924-932 |
Sentence |
denotes |
Results: |
TextSentencer_T9 |
933-1063 |
Sentence |
denotes |
Early COVID-19 cases kept an increase in exponential growth manner before 26 January, 2020, then the increase trend became slower. |
TextSentencer_T10 |
1064-1110 |
Sentence |
denotes |
The average incubation period was 5.01 (95%CI: |
TextSentencer_T11 |
1111-1176 |
Sentence |
denotes |
4.31-5.69) days; the average generation interval was 6.03 (95%CI: |
TextSentencer_T12 |
1177-1193 |
Sentence |
denotes |
5.20-6.91) days. |
TextSentencer_T13 |
1194-1256 |
Sentence |
denotes |
The basic reproduction number was estimated to be 3.74 (95%CI: |
TextSentencer_T14 |
1257-1281 |
Sentence |
denotes |
3.63-3.87), 3.16 (95%CI: |
TextSentencer_T15 |
1282-1310 |
Sentence |
denotes |
2.90-3.43), and 3.91 (95%CI: |
TextSentencer_T16 |
1311-1353 |
Sentence |
denotes |
3.71-4.11) by three methods, respectively. |
TextSentencer_T17 |
1354-1366 |
Sentence |
denotes |
Conclusions: |
TextSentencer_T18 |
1367-1544 |
Sentence |
denotes |
The Gamma distribution fits both the generation interval and incubation period best, and the mean value of generation interval is 1.02 day longer than that of incubation period. |
TextSentencer_T19 |
1545-1765 |
Sentence |
denotes |
The relatively high basic reproduction number indicates that the epidemic is still serious; Based on our analysis, the turning point of the epidemic would be seen on 26 January, the growth rate would be lower afterwards. |