LitCovid-sentences-v1  

PubMed:32105632 JSONTXT 16 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-153 Sentence denotes Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.
TextSentencer_T2 154-165 Sentence denotes BACKGROUND:
TextSentencer_T3 166-314 Sentence denotes An ongoing outbreak of pneumonia associated with the severe acute respiratory coronavirus 2 (SARS-CoV-2) started in December, 2019, in Wuhan, China.
TextSentencer_T4 315-393 Sentence denotes Information about critically ill patients with SARS-CoV-2 infection is scarce.
TextSentencer_T5 394-501 Sentence denotes We aimed to describe the clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia.
TextSentencer_T6 502-510 Sentence denotes METHODS:
TextSentencer_T7 511-785 Sentence denotes In this single-centered, retrospective, observational study, we enrolled 52 critically ill adult patients with SARS-CoV-2 pneumonia who were admitted to the intensive care unit (ICU) of Wuhan Jin Yin-tan hospital (Wuhan, China) between late December, 2019, and Jan 26, 2020.
TextSentencer_T8 786-901 Sentence denotes Demographic data, symptoms, laboratory values, comorbidities, treatments, and clinical outcomes were all collected.
TextSentencer_T9 902-957 Sentence denotes Data were compared between survivors and non-survivors.
TextSentencer_T10 958-1018 Sentence denotes The primary outcome was 28-day mortality, as of Feb 9, 2020.
TextSentencer_T11 1019-1186 Sentence denotes Secondary outcomes included incidence of SARS-CoV-2-related acute respiratory distress syndrome (ARDS) and the proportion of patients requiring mechanical ventilation.
TextSentencer_T12 1187-1196 Sentence denotes FINDINGS:
TextSentencer_T13 1197-1287 Sentence denotes Of 710 patients with SARS-CoV-2 pneumonia, 52 critically ill adult patients were included.
TextSentencer_T14 1288-1414 Sentence denotes The mean age of the 52 patients was 59·7 (SD 13·3) years, 35 (67%) were men, 21 (40%) had chronic illness, 51 (98%) had fever.
TextSentencer_T15 1415-1577 Sentence denotes 32 (61·5%) patients had died at 28 days, and the median duration from admission to the intensive care unit (ICU) to death was 7 (IQR 3-11) days for non-survivors.
TextSentencer_T16 1578-1866 Sentence denotes Compared with survivors, non-survivors were older (64·6 years [11·2] vs 51·9 years [12·9]), more likely to develop ARDS (26 [81%] patients vs 9 [45%] patients), and more likely to receive mechanical ventilation (30 [94%] patients vs 7 [35%] patients), either invasively or non-invasively.
TextSentencer_T17 1867-2067 Sentence denotes Most patients had organ function damage, including 35 (67%) with ARDS, 15 (29%) with acute kidney injury, 12 (23%) with cardiac injury, 15 (29%) with liver dysfunction, and one (2%) with pneumothorax.
TextSentencer_T18 2068-2118 Sentence denotes 37 (71%) patients required mechanical ventilation.
TextSentencer_T19 2119-2182 Sentence denotes Hospital-acquired infection occurred in seven (13·5%) patients.
TextSentencer_T20 2183-2198 Sentence denotes INTERPRETATION:
TextSentencer_T21 2199-2282 Sentence denotes The mortality of critically ill patients with SARS-CoV-2 pneumonia is considerable.
TextSentencer_T22 2283-2375 Sentence denotes The survival time of the non-survivors is likely to be within 1-2 weeks after ICU admission.
TextSentencer_T23 2376-2462 Sentence denotes Older patients (>65 years) with comorbidities and ARDS are at increased risk of death.
TextSentencer_T24 2463-2619 Sentence denotes The severity of SARS-CoV-2 pneumonia poses great strain on critical care resources in hospitals, especially if they are not adequately staffed or resourced.
TextSentencer_T25 2620-2628 Sentence denotes FUNDING:
TextSentencer_T26 2629-2634 Sentence denotes None.