| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T456 |
0-123 |
Sentence |
denotes |
From the structural point of view ACE2 is closely related to ACE, and its discovery was a by-product of ACE investigations. |
| T457 |
124-238 |
Sentence |
denotes |
However, this macromolecule has soon showed peculiar functional properties and has attracted increasing attention. |
| T458 |
239-490 |
Sentence |
denotes |
The expression of ACE2 in the heart, kidney and vascular system pointed to a role in the regulation of blood pressure and cardiovascular homeostasis, possibly as a counterbalance to ACE activation, but this hypothesis now appears to be too simplistic. |
| T459 |
491-689 |
Sentence |
denotes |
Additional functions of ACE2 are strongly suggested by its capability to modulate cytokine metabolism and the inflammatory reaction, as well as by its remarkable expression in the respiratory tract. |
