| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T234 |
0-197 |
Sentence |
denotes |
On the basis of the strong similarity between the S proteins of SARS-CoV and SARS-CoV-2, many researchers early set-out to demonstrate whether both viruses target the same host cell receptor, ACE2. |
| T235 |
198-356 |
Sentence |
denotes |
Zhou et al. (2020) highlighted that the virus was able to infect cell lines only when they expressed human, bat, civet, and pig (but not mouse) ACE2 receptor. |
| T236 |
357-548 |
Sentence |
denotes |
Hoffmann et al. (2020b), Ou et al. (2020), and Walls et al. (2020) elegantly outlined that the BHK cell line could be infected by pseudotyped SARS-CoV-2 or SARS-CoV only upon ACE2 expression. |
| T237 |
549-754 |
Sentence |
denotes |
Conversely, the expression of different human receptors used by other CoVs (hDPP4 and APN, used by MERS CoV and HCoV-229E, respectively) did not enable pseudovirus access to cells (Hoffmann et al., 2020b). |
| T238 |
755-849 |
Sentence |
denotes |
Taken together, these findings are solid evidence that SARS-CoV-2 engages ACE2 for cell entry. |
