PMC:7443692 / 25589-26946 JSONTXT 10 Projects

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Id Subject Object Predicate Lexical cue
T145 142-334 Sentence denotes Results from glycomics and glycoproteomics experiments were combined with results from bioinformatics analyses and used to model several versions of glycosylated SARS-CoV-2 S trimer immunogen.
T146 335-442 Sentence denotes (A) Sequence of the SARS-CoV-2 S immunogen displaying computed antigen accessibility and other information.
T147 443-524 Sentence denotes Antigen accessibility is indicated by red shading across the amino acid sequence.
T148 525-728 Sentence denotes (B) Emerging variants confirmed by independent sequencing experiments were analyzed based on the 3D structure of SARS-CoV-2 S to generate a proximity chart to the determined N-linked glycosylation sites.
T149 729-942 Sentence denotes (C) SARS-CoV-2 S trimer immunogen model from MD simulation displaying abundance glycoforms and antigen accessibility shaded in red for most accessible, white for partial, and black for inaccessible (see Video S1).
T150 943-1059 Sentence denotes (D) SARS-CoV-2 S trimer immunogen model from MD simulation displaying Oxford Class glycoforms and sequence variants.
T151 1060-1185 Sentence denotes Asterisk indicates not visible, whereas the box represents three amino acid variants that are clustered together in 3D space.
T152 1186-1357 Sentence denotes (E) SARS-CoV-2 S trimer immunogen model from MD simulation displaying processed glycoforms plus shading of Thr-323 that has O-glycosylation at low stoichiometry in yellow.