| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T144 |
0-150 |
Sentence |
denotes |
Figure 4 3D Structural Modeling of Glycosylated SARS-CoV-2 Spike Trimer Immunogen Reveals Predictions for Antigen Accessibility and Other Key Features |
| T145 |
151-343 |
Sentence |
denotes |
Results from glycomics and glycoproteomics experiments were combined with results from bioinformatics analyses and used to model several versions of glycosylated SARS-CoV-2 S trimer immunogen. |
| T146 |
344-451 |
Sentence |
denotes |
(A) Sequence of the SARS-CoV-2 S immunogen displaying computed antigen accessibility and other information. |
| T147 |
452-533 |
Sentence |
denotes |
Antigen accessibility is indicated by red shading across the amino acid sequence. |
| T148 |
534-737 |
Sentence |
denotes |
(B) Emerging variants confirmed by independent sequencing experiments were analyzed based on the 3D structure of SARS-CoV-2 S to generate a proximity chart to the determined N-linked glycosylation sites. |
| T149 |
738-951 |
Sentence |
denotes |
(C) SARS-CoV-2 S trimer immunogen model from MD simulation displaying abundance glycoforms and antigen accessibility shaded in red for most accessible, white for partial, and black for inaccessible (see Video S1). |
| T150 |
952-1068 |
Sentence |
denotes |
(D) SARS-CoV-2 S trimer immunogen model from MD simulation displaying Oxford Class glycoforms and sequence variants. |
| T151 |
1069-1194 |
Sentence |
denotes |
Asterisk indicates not visible, whereas the box represents three amino acid variants that are clustered together in 3D space. |
| T152 |
1195-1366 |
Sentence |
denotes |
(E) SARS-CoV-2 S trimer immunogen model from MD simulation displaying processed glycoforms plus shading of Thr-323 that has O-glycosylation at low stoichiometry in yellow. |
