LitCovid-sample-sentences  

PMC:7443692 / 24844-26946 JSONTXT 12 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T139 0-98 Sentence denotes The three glycoform models were subjected to multiple all-atom MD simulations with explicit water.
T140 99-225 Sentence denotes Information from analyses of these structures is presented in Figure 4 A along with the sequence of the SARS-CoV-2 S protomer.
T141 226-335 Sentence denotes We also determined variants in S that are emerging in the virus that have been sequenced to date (Table S11).
T142 336-511 Sentence denotes The inter-residue distances were measured between the most α-carbon-distal atoms of the N-glycan sites and Spike glycoprotein population variant sites in 3D space (Figure 4B).
T143 512-735 Sentence denotes Notable from this analysis, there are several variants that don’t ablate the N-linked sequon but are sufficiently close in 3D space to N-glycosites, such as D138H, H655Y, S939F, and L1203F, to warrant further investigation.
T144 736-886 Sentence denotes Figure 4 3D Structural Modeling of Glycosylated SARS-CoV-2 Spike Trimer Immunogen Reveals Predictions for Antigen Accessibility and Other Key Features
T145 887-1079 Sentence denotes Results from glycomics and glycoproteomics experiments were combined with results from bioinformatics analyses and used to model several versions of glycosylated SARS-CoV-2 S trimer immunogen.
T146 1080-1187 Sentence denotes (A) Sequence of the SARS-CoV-2 S immunogen displaying computed antigen accessibility and other information.
T147 1188-1269 Sentence denotes Antigen accessibility is indicated by red shading across the amino acid sequence.
T148 1270-1473 Sentence denotes (B) Emerging variants confirmed by independent sequencing experiments were analyzed based on the 3D structure of SARS-CoV-2 S to generate a proximity chart to the determined N-linked glycosylation sites.
T149 1474-1687 Sentence denotes (C) SARS-CoV-2 S trimer immunogen model from MD simulation displaying abundance glycoforms and antigen accessibility shaded in red for most accessible, white for partial, and black for inaccessible (see Video S1).
T150 1688-1804 Sentence denotes (D) SARS-CoV-2 S trimer immunogen model from MD simulation displaying Oxford Class glycoforms and sequence variants.
T151 1805-1930 Sentence denotes Asterisk indicates not visible, whereas the box represents three amino acid variants that are clustered together in 3D space.
T152 1931-2102 Sentence denotes (E) SARS-CoV-2 S trimer immunogen model from MD simulation displaying processed glycoforms plus shading of Thr-323 that has O-glycosylation at low stoichiometry in yellow.