| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T96 |
0-313 |
Sentence |
denotes |
Although dN/dS estimates are comparable within each viral outbreak, they are not directly comparable between viral families as they can only be considered in the environment in which they are measured (i.e. multiple differences in transmission ecology and host-virus interactions disallow meaningful comparisons). |
| T97 |
314-487 |
Sentence |
denotes |
For example, differences in the epidemic behaviour and host immune environment of MERS and SARS outbreaks likely contribute to the observed genetic diversity and thus dN/dS. |
| T98 |
488-597 |
Sentence |
denotes |
MERS was characterized by repeated spillover events from camels into humans, where it circulated transiently. |
| T99 |
598-719 |
Sentence |
denotes |
In contrast, the SARS outbreak corresponded to a single zoonotic event followed by extensive human-to-human transmission. |
| T100 |
720-837 |
Sentence |
denotes |
Consequently, inferring the degree of selection acting upon MERS and SARS from dN/dS analysis is extremely difficult. |
| T101 |
838-1142 |
Sentence |
denotes |
Importantly, while similar analyses of SARS-CoV-2 is desirable, due to the low genetic variation among the current SARS-CoV-2 sequences (as of 17 March 2020), which likely include deleterious mutations that will be removed by selection over time, the resulting bioinformatic analyses would be unreliable. |
