| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T99 |
0-439 |
Sentence |
denotes |
FcγRIIc is an activating FcγR whose expression is regulated single nucleotide polymorphism that permits expression in approximately 20% of humans and in whom it is present at low levels on natural killer (NK) and B cells.11 It has arisen by gene duplication/recombination resulting in an extracellular region derived from FcγRIIb, which binds IgG4, and with an ITAM‐containing cytoplasmic tail related to the activating receptor FcγRIIa. |
| T100 |
440-558 |
Sentence |
denotes |
Thus FcγRIIc provides IgG4 with an activation receptor pathway and confers a new biology of IgG4 in these individuals. |
| T101 |
559-691 |
Sentence |
denotes |
Its low frequency in the population may also confound in vivo mAb clinical testing or use, but as yet there is no evidence for this. |
