PMC:7228307 / 15170-15939 JSONTXT 18 Projects

Annnotations TAB TSV DIC JSON TextAE-old TextAE

Id Subject Object Predicate Lexical cue
T94 0-125 Sentence denotes FcγRIIa is expressed only in primates and shows the broadest expression of all FcγRs, being present on all innate leukocytes.
T95 126-268 Sentence denotes It is also present on platelets but its role in effector functions is not established but it is important in certain immune thrombocytopenias.
T96 269-347 Sentence denotes A polymorphic form of this receptor is the only human receptor for human IgG2.
T97 348-522 Sentence denotes This, together with its limited species expression and unique ITAM‐containing cytoplasmic tail (reviewed by Anania et al. 11), suggests a unique function in human leukocytes.
T98 523-769 Sentence denotes Interestingly, polymorphism of the receptor is associated with systemic lupus erythematosus and resistance to Gram‐negative organisms.11 A rare, hyper‐responsive form is a risk factor for neutrophil‐driven anaphylaxis in Ig replacement therapy.22