Id |
Subject |
Object |
Predicate |
Lexical cue |
T104 |
0-19 |
Sentence |
denotes |
4.1.2.2 Rationale: |
T105 |
20-76 |
Sentence |
denotes |
Bat serum is not able to efficiently neutralize SARS-CoV |
T106 |
77-213 |
Sentence |
denotes |
The range of bats, belonging to the genus Rhinolophus (horseshoe bats) and the family Rhinolophidae, produce the SARS-CoV antibody [12]. |
T107 |
214-404 |
Sentence |
denotes |
Polymerase chain reaction (PCR) will confirm the presence of SARS-CoV nucleocapsid (N) and polymerase (P) proteins in fecal samples if an individual bat being seropositive for SARS-CoV [12]. |
T108 |
405-611 |
Sentence |
denotes |
There is a significant degree of resemblance of greater than 90% in the nucleotide sequence of the viral genomes between SL-CoV Rp3 [12] and the Tor2 strain of SARS-CoV – which was isolated in Toronto [15]. |
T109 |
612-824 |
Sentence |
denotes |
The differences in the genome sequences of SARS-CoV in the two species occur merely in the S gene – which encodes the S1 domain of the coronavirus spike protein and contains regions with high mutation rates [12]. |
T110 |
825-1053 |
Sentence |
denotes |
The coronaviruses commonly possess five open reading frames (ORF) that correlate with the production of the replicase polyprotein (P), the spike (S), envelope (E), and membrane (M) glycoproteins and the nucleocapsid (N) protein. |
T111 |
1054-1211 |
Sentence |
denotes |
The human SARS-CoV Tor2 and bat SL-CoV Rp3 strains remain more than 90% identical at the proteins P, E, M, and N. the protein S consists of two main domains: |
T112 |
1212-1351 |
Sentence |
denotes |
1) the S1 domain conveys the role of receptor binding and 2) the S2 domain assumes the role of the fusion of viral and host-cell membranes. |
T113 |
1352-1486 |
Sentence |
denotes |
In particular, the human SARS-CoV Tor2 strain shows a noticeable degree of difference in the S1 domain from the bat SL-CoV Rp3 strain. |
T114 |
1487-1703 |
Sentence |
denotes |
This diversity would suffice to produce functional differences between the species, and is an apparent reason why bat sera having high levels of cross-reactive antibodies not acted efficiently to neutralize SARS-CoV. |