| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T12 |
0-216 |
Sentence |
denotes |
The emergence of the betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), represents a considerable threat to global human health. |
| T13 |
217-378 |
Sentence |
denotes |
Vaccine development is focused on the principal target of the humoral immune response, the spike (S) glycoprotein, which mediates cell entry and membrane fusion. |
| T14 |
379-513 |
Sentence |
denotes |
The SARS-CoV-2 S gene encodes 22 N-linked glycan sequons per protomer, which likely play a role in protein folding and immune evasion. |
| T15 |
514-643 |
Sentence |
denotes |
Here, using a site-specific mass spectrometric approach, we reveal the glycan structures on a recombinant SARS-CoV-2 S immunogen. |
| T16 |
644-738 |
Sentence |
denotes |
This analysis enables mapping of the glycan-processing states across the trimeric viral spike. |
| T17 |
739-885 |
Sentence |
denotes |
We show how SARS-CoV-2 S glycans differ from typical host glycan processing, which may have implications in viral pathobiology and vaccine design. |
