PMC:7199903 / 8448-9190 21 Projects
Annnotations
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T59 | 0-75 | Sentence | denotes | Two sites on SARS-CoV-2 S are principally oligomannose-type: N234 and N709. |
| T60 | 76-468 | Sentence | denotes | The predominant oligomannose-type glycan structure observed across the protein, with the exception of N234, is Man5GlcNAc2 (Man, mannose; GlcNAc, N-acetylglucosamine), which demonstrates that these sites are largely accessible to α-1,2-mannosidases but are poor substrates for GlcNAcT-I, which is the gateway enzyme in the formation of hybrid- and complex-type glycans in the Golgi apparatus. |
| T61 | 469-595 | Sentence | denotes | The stage at which processing is impeded is a signature related to the density and presentation of glycans on the viral spike. |
| T62 | 596-742 | Sentence | denotes | For example, the more densely glycosylated spikes of HIV-1 Env and Lassa virus (LASV) GPC exhibit numerous sites dominated by Man9GlcNAc2 (21–24). |