PMC:7199903 / 2725-3679 JSONTXT 19 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T23 0-146 Sentence denotes Viral glycosylation has wide-ranging roles in viral pathobiology, including mediating protein folding and stability and shaping viral tropism (9).
T24 147-290 Sentence denotes Glycosylation sites are under selective pressure as they facilitate immune evasion by shielding specific epitopes from antibody neutralization.
T25 291-436 Sentence denotes However, we note the low mutation rate of SARS-CoV-2 and that as yet, there have been no observed mutations to N-linked glycosylation sites (10).
T26 437-535 Sentence denotes Surfaces with an unusually high density of glycans can also enable immune recognition (9, 11, 12).
T27 536-661 Sentence denotes The role of glycosylation in camouflaging immunogenic protein epitopes has been studied for other coronaviruses (10, 13, 14).
T28 662-781 Sentence denotes Coronaviruses form virions by budding into the lumen of endoplasmic reticulum–Golgi intermediate compartments (15, 16).
T29 782-954 Sentence denotes However, observations of complex-type glycans on virally derived material suggests that the viral glycoproteins are subjected to Golgi-resident processing enzymes (13, 17).