PMC:7228307 / 59629-62087 18 Projects
Annnotations
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T356 | 0-6 | NNP | denotes | Future |
T357 | 7-18 | NNP | denotes | Engineering |
T358 | 19-29 | NNPS | denotes | Strategies |
T359 | 30-40 | JJ | denotes | Monoclonal |
T360 | 41-51 | NNS | denotes | antibodies |
T361 | 52-55 | VBP | denotes | are |
T362 | 56-62 | JJ | denotes | potent |
T363 | 63-75 | NNS | denotes | therapeutics |
T364 | 76-78 | IN | denotes | in |
T365 | 79-80 | DT | denotes | a |
T366 | 81-87 | NN | denotes | number |
T367 | 88-90 | IN | denotes | of |
T368 | 91-98 | JJ | denotes | chronic |
T369 | 99-101 | CC | denotes | or |
T370 | 102-106 | RB | denotes | once |
T371 | 107-116 | JJ | denotes | incurable |
T372 | 117-125 | NNS | denotes | diseases |
T373 | 127-134 | RB | denotes | However |
T374 | 134-135 | -COMMA- | denotes | , |
T375 | 136-141 | EX | denotes | there |
T376 | 142-144 | VBZ | denotes | is |
T377 | 145-150 | RB | denotes | still |
T378 | 151-160 | JJ | denotes | extensive |
T379 | 161-166 | JJ | denotes | unmet |
T380 | 167-175 | JJ | denotes | clinical |
T381 | 176-180 | NN | denotes | need |
T382 | 181-183 | RB | denotes | as |
T383 | 184-188 | RB | denotes | well |
T384 | 189-191 | IN | denotes | as |
T385 | 192-204 | JJ | denotes | considerable |
T386 | 205-209 | NN | denotes | room |
T387 | 210-213 | IN | denotes | for |
T388 | 214-225 | NN | denotes | improvement |
T389 | 226-228 | IN | denotes | in |
T390 | 229-233 | JJ | denotes | many |
T391 | 234-242 | VBG | denotes | existing |
T392 | 243-255 | NNS | denotes | therapeutics |
T393 | 257-264 | JJ | denotes | Further |
T394 | 265-278 | NN | denotes | understanding |
T395 | 279-281 | IN | denotes | of |
T396 | 282-285 | WRB | denotes | how |
T397 | 286-294 | NN | denotes | antibody |
T398 | 295-304 | NN | denotes | structure |
T399 | 305-312 | VBZ | denotes | affects |
T400 | 313-317 | NN | denotes | FcγR |
T401 | 318-326 | NN | denotes | function |
T402 | 327-329 | VBZ | denotes | is |
T403 | 330-339 | JJ | denotes | essential |
T404 | 340-343 | IN | denotes | for |
T405 | 344-350 | JJ | denotes | future |
T406 | 351-362 | NN | denotes | development |
T407 | 363-365 | IN | denotes | of |
T408 | 366-370 | RBR | denotes | more |
T409 | 371-377 | JJ | denotes | potent |
T410 | 378-381 | CC | denotes | and |
T411 | 382-391 | JJ | denotes | effective |
T412 | 392-396 | NNS | denotes | mAbs |
T413 | 398-405 | RB | denotes | Already |
T414 | 405-406 | -COMMA- | denotes | , |
T415 | 407-418 | NN | denotes | engineering |
T416 | 419-421 | IN | denotes | of |
T417 | 422-425 | DT | denotes | the |
T418 | 426-429 | NN | denotes | IgG |
T419 | 430-432 | NN | denotes | Fc |
T420 | 433-436 | CC | denotes | and |
T421 | 437-440 | PRP-DOLLAR- | denotes | its |
T422 | 441-447 | NN | denotes | glycan |
T423 | 448-451 | VBZ | denotes | has |
T424 | 452-458 | VBN | denotes | proved |
T425 | 459-460 | DT | denotes | a |
T426 | 461-467 | JJ | denotes | potent |
T427 | 468-471 | CC | denotes | and |
T428 | 472-481 | JJ | denotes | effective |
T429 | 482-490 | NN | denotes | approach |
T430 | 491-494 | IN | denotes | for |
T431 | 495-505 | VBG | denotes | increasing |
T432 | 506-509 | DT | denotes | the |
T433 | 510-518 | JJ | denotes | clinical |
T434 | 519-532 | NN | denotes | effectiveness |
T435 | 532-533 | -COMMA- | denotes | , |
T436 | 534-544 | JJ | denotes | functional |
T437 | 545-556 | NN | denotes | specificity |
T438 | 557-560 | CC | denotes | and |
T439 | 561-567 | NN | denotes | safety |
T440 | 568-570 | IN | denotes | of |
T441 | 571-582 | JJ | denotes | therapeutic |
T442 | 583-587 | NNS | denotes | mAbs |
T443 | 588-591 | CC | denotes | and |
T444 | 592-594 | VBZ | denotes | is |
T445 | 595-597 | DT | denotes | an |
T446 | 598-606 | VBG | denotes | emerging |
T447 | 607-614 | NN | denotes | pathway |
T448 | 615-617 | TO | denotes | to |
T449 | 618-621 | DT | denotes | the |
T450 | 622-633 | NN | denotes | development |
T451 | 634-636 | IN | denotes | of |
T452 | 637-640 | DT | denotes | the |
T453 | 641-651 | NN | denotes | “next‐gen” |
T454 | 652-664 | NNS | denotes | therapeutics |
T455 | 666-672 | JJ | denotes | Future |
T456 | 673-683 | NNS | denotes | directions |
T457 | 684-686 | IN | denotes | in |
T458 | 687-690 | DT | denotes | the |
T459 | 691-702 | NN | denotes | development |
T460 | 703-706 | CC | denotes | and |
T461 | 707-710 | NN | denotes | use |
T462 | 711-713 | IN | denotes | of |
T463 | 714-725 | JJ | denotes | therapeutic |
T464 | 726-736 | NNS | denotes | antibodies |
T465 | 737-743 | MD | denotes | should |
T466 | 744-756 | RB | denotes | increasingly |
T467 | 757-762 | VB | denotes | mimic |
T468 | 763-769 | JJ | denotes | normal |
T469 | 770-780 | JJ | denotes | protective |
T470 | 781-789 | NN | denotes | antibody |
T471 | 790-799 | NNS | denotes | responses |
T472 | 799-800 | -COMMA- | denotes | , |
T473 | 801-806 | WDT | denotes | which |
T474 | 807-810 | VBP | denotes | are |
T475 | 811-821 | JJ | denotes | polyclonal |
T476 | 822-825 | CC | denotes | and |
T477 | 826-834 | VBN | denotes | elicited |
T478 | 835-837 | IN | denotes | in |
T479 | 838-841 | DT | denotes | the |
T480 | 842-849 | NN | denotes | context |
T481 | 850-852 | IN | denotes | of |
T482 | 853-859 | JJ | denotes | innate |
T483 | 860-868 | NN | denotes | receptor |
T484 | 869-879 | NN | denotes | engagement |
T485 | 880-885 | WDT | denotes | which |
T486 | 886-894 | VBZ | denotes | includes |
T487 | 895-898 | DT | denotes | the |
T488 | 899-902 | NNS | denotes | FcR |
T489 | 903-905 | RB | denotes | as |
T490 | 906-910 | RB | denotes | well |
T491 | 911-913 | IN | denotes | as |
T492 | 914-919 | JJ | denotes | other |
T493 | 920-930 | RB | denotes | powerfully |
T494 | 931-941 | JJ | denotes | responsive |
T495 | 942-949 | NNS | denotes | systems |
T496 | 950-959 | VBG | denotes | including |
T497 | 960-963 | DT | denotes | the |
T498 | 964-973 | JJ | denotes | Toll‐like |
T499 | 974-983 | NNS | denotes | receptors |
T500 | 984-987 | CC | denotes | and |
T501 | 988-998 | NN | denotes | complement |
T502 | 999-1008 | NNS | denotes | receptors |
T503 | 1010-1021 | RB | denotes | Furthermore |
T504 | 1021-1022 | -COMMA- | denotes | , |
T505 | 1023-1026 | DT | denotes | the |
T506 | 1027-1032 | JJ | denotes | mixed |
T507 | 1033-1041 | NN | denotes | subclass |
T508 | 1042-1048 | NN | denotes | nature |
T509 | 1049-1051 | IN | denotes | of |
T510 | 1052-1057 | DT | denotes | these |
T511 | 1058-1064 | JJ | denotes | normal |
T512 | 1065-1073 | NN | denotes | antibody |
T513 | 1074-1083 | NNS | denotes | responses |
T514 | 1084-1092 | VBZ | denotes | suggests |
T515 | 1093-1097 | IN | denotes | that |
T516 | 1098-1111 | NNS | denotes | circumstances |
T517 | 1112-1115 | MD | denotes | may |
T518 | 1116-1121 | VB | denotes | arise |
T519 | 1122-1124 | IN | denotes | in |
T520 | 1125-1136 | JJ | denotes | therapeutic |
T521 | 1137-1147 | NNS | denotes | strategies |
T522 | 1148-1153 | WRB | denotes | where |
T523 | 1154-1159 | EX | denotes | there |
T524 | 1160-1162 | VBZ | denotes | is |
T525 | 1163-1168 | NN | denotes | value |
T526 | 1169-1171 | IN | denotes | in |
T527 | 1172-1178 | VBG | denotes | having |
T528 | 1179-1189 | RB | denotes | distinctly |
T529 | 1190-1198 | VBN | denotes | modified |
T530 | 1199-1202 | NNS | denotes | Fcs |
T531 | 1203-1206 | IN | denotes | for |
T532 | 1207-1210 | DT | denotes | the |
T533 | 1211-1218 | JJ | denotes | nuanced |
T534 | 1219-1229 | NN | denotes | engagement |
T535 | 1230-1232 | IN | denotes | of |
T536 | 1233-1242 | JJ | denotes | different |
T537 | 1243-1247 | NN | denotes | FcγR |
T538 | 1248-1254 | NN | denotes | family |
T539 | 1255-1262 | NNS | denotes | members |
T540 | 1264-1274 | NNS | denotes | Treatments |
T541 | 1275-1285 | VBG | denotes | comprising |
T542 | 1286-1294 | JJ | denotes | multiple |
T543 | 1295-1299 | NNS | denotes | mAbs |
T544 | 1300-1303 | CC | denotes | and |
T545 | 1304-1310 | JJ | denotes | immune |
T546 | 1311-1321 | NNS | denotes | stimulants |
T547 | 1322-1325 | VBP | denotes | are |
T548 | 1326-1331 | IN | denotes | under |
T549 | 1332-1345 | NN | denotes | investigation |
T550 | 1346-1348 | IN | denotes | in |
T551 | 1349-1359 | JJ | denotes | infectious |
T552 | 1360-1367 | NN | denotes | disease |
T553 | 1368-1371 | IN | denotes | for |
T554 | 1372-1386 | NN | denotes | neutralization |
T555 | 1387-1395 | NN | denotes | coverage |
T556 | 1396-1398 | IN | denotes | of |
T557 | 1399-1406 | JJ | denotes | variant |
T558 | 1407-1414 | NNS | denotes | strains |
T559 | 1416-1422 | RB | denotes | Indeed |
T560 | 1422-1423 | -COMMA- | denotes | , |
T561 | 1424-1428 | PDT | denotes | such |
T562 | 1429-1431 | DT | denotes | an |
T563 | 1432-1440 | NN | denotes | approach |
T564 | 1441-1444 | MD | denotes | may |
T565 | 1445-1447 | VB | denotes | be |
T566 | 1448-1452 | RBS | denotes | most |
T567 | 1453-1462 | JJ | denotes | effective |
T568 | 1463-1465 | IN | denotes | in |
T569 | 1466-1474 | VBG | denotes | emerging |
T570 | 1475-1485 | JJ | denotes | infectious |
T571 | 1486-1493 | NN | denotes | disease |
T572 | 1494-1498 | JJ | denotes | such |
T573 | 1499-1501 | IN | denotes | as |
T574 | 1502-1508 | JJ | denotes | severe |
T575 | 1509-1514 | JJ | denotes | acute |
T576 | 1515-1526 | JJ | denotes | respiratory |
T577 | 1527-1535 | NN | denotes | syndrome |
T578 | 1536-1547 | NN | denotes | coronavirus |
T579 | 1548-1549 | CD | denotes | 2 |
T580 | 1550-1551 | -LRB- | denotes | ( |
T581 | 1551-1561 | NN | denotes | SARS‐CoV‐2 |
T582 | 1561-1562 | -RRB- | denotes | ) |
T583 | 1563-1572 | NN | denotes | infection |
T584 | 1574-1577 | DT | denotes | The |
T585 | 1578-1581 | NN | denotes | use |
T586 | 1582-1584 | IN | denotes | of |
T587 | 1585-1593 | JJ | denotes | multiple |
T588 | 1594-1598 | NNS | denotes | mAbs |
T589 | 1599-1607 | VBN | denotes | tailored |
T590 | 1608-1611 | IN | denotes | for |
T591 | 1612-1620 | JJ | denotes | distinct |
T592 | 1621-1629 | NN | denotes | effector |
T593 | 1630-1639 | NNS | denotes | functions |
T594 | 1640-1643 | CC | denotes | and |
T595 | 1644-1653 | VBG | denotes | targeting |
T596 | 1654-1663 | JJ | denotes | different |
T597 | 1664-1672 | NNS | denotes | epitopes |
T598 | 1673-1677 | MD | denotes | will |
T599 | 1678-1686 | VB | denotes | maximize |
T600 | 1687-1690 | DT | denotes | the |
T601 | 1691-1702 | NN | denotes | opportunity |
T602 | 1703-1706 | IN | denotes | for |
T603 | 1707-1718 | NN | denotes | cocktailing |
T604 | 1719-1721 | IN | denotes | of |
T605 | 1722-1730 | NN | denotes | effector |
T606 | 1731-1740 | NNS | denotes | functions |
T607 | 1741-1743 | IN | denotes | in |
T608 | 1744-1753 | JJ | denotes | different |
T609 | 1754-1759 | NNS | denotes | types |
T610 | 1760-1762 | IN | denotes | of |
T611 | 1763-1771 | NNS | denotes | diseases |
T612 | 1773-1779 | RB | denotes | Indeed |
T613 | 1779-1780 | -COMMA- | denotes | , |
T614 | 1781-1783 | IN | denotes | in |
T615 | 1784-1785 | DT | denotes | a |
T616 | 1786-1791 | JJ | denotes | small |
T617 | 1792-1795 | CC | denotes | but |
T618 | 1796-1808 | JJ | denotes | contemporary |
T619 | 1809-1816 | NN | denotes | example |
T620 | 1817-1824 | IN | denotes | outside |
T621 | 1825-1827 | IN | denotes | of |
T622 | 1828-1838 | JJ | denotes | infectious |
T623 | 1839-1846 | NN | denotes | disease |
T624 | 1846-1847 | -COMMA- | denotes | , |
T625 | 1848-1851 | DT | denotes | the |
T626 | 1852-1864 | NNP | denotes | FDA‐approved |
T627 | 1865-1876 | NN | denotes | combination |
T628 | 1877-1879 | IN | denotes | in |
T629 | 1880-1894 | NN | denotes | adenocarcinoma |
T630 | 1895-1902 | NN | denotes | therapy |
T631 | 1903-1907 | VBZ | denotes | uses |
T632 | 1908-1909 | DT | denotes | a |
T633 | 1910-1918 | NN | denotes | cocktail |
T634 | 1919-1921 | IN | denotes | of |
T635 | 1922-1925 | CD | denotes | two |
T636 | 1926-1930 | NNS | denotes | mAbs |
T637 | 1930-1931 | -COMMA- | denotes | , |
T638 | 1932-1942 | NN | denotes | pertuzumab |
T639 | 1943-1946 | CC | denotes | and |
T640 | 1947-1958 | NN | denotes | trastuzumab |
T641 | 1958-1959 | -COMMA- | denotes | , |
T642 | 1960-1967 | IN | denotes | against |
T643 | 1968-1976 | NN | denotes | Her2.123 |
T644 | 1977-1983 | RB | denotes | Rather |
T645 | 1984-1988 | IN | denotes | than |
T646 | 1989-1992 | CD | denotes | one |
T647 | 1993-1997 | NN | denotes | type |
T648 | 1998-2000 | IN | denotes | of |
T649 | 2001-2003 | NN | denotes | Fc |
T650 | 2004-2006 | TO | denotes | to |
T651 | 2007-2014 | VB | denotes | conquer |
T652 | 2015-2018 | DT | denotes | all |
T653 | 2018-2019 | -COMMA- | denotes | , |
T654 | 2020-2023 | DT | denotes | the |
T655 | 2024-2032 | JJ | denotes | combined |
T656 | 2033-2036 | NN | denotes | use |
T657 | 2037-2039 | IN | denotes | of |
T658 | 2040-2053 | RB | denotes | appropriately |
T659 | 2054-2062 | VBN | denotes | selected |
T660 | 2063-2067 | NNS | denotes | mAbs |
T661 | 2068-2073 | WP-DOLLAR- | denotes | whose |
T662 | 2074-2084 | JJ | denotes | individual |
T663 | 2085-2095 | NNS | denotes | components |
T664 | 2096-2099 | VBP | denotes | are |
T665 | 2100-2108 | VBN | denotes | enhanced |
T666 | 2109-2112 | IN | denotes | for |
T667 | 2113-2116 | DT | denotes | the |
T668 | 2117-2127 | NN | denotes | engagement |
T669 | 2128-2130 | IN | denotes | of |
T670 | 2131-2140 | JJ | denotes | different |
T671 | 2141-2145 | NN | denotes | FcγR |
T672 | 2146-2153 | NNS | denotes | members |
T673 | 2154-2157 | MD | denotes | may |
T674 | 2158-2165 | VB | denotes | utilize |
T675 | 2166-2174 | JJ | denotes | multiple |
T676 | 2175-2185 | NNS | denotes | components |
T677 | 2186-2188 | IN | denotes | of |
T678 | 2189-2192 | DT | denotes | the |
T679 | 2193-2201 | NN | denotes | spectrum |
T680 | 2202-2204 | IN | denotes | of |
T681 | 2205-2213 | NN | denotes | effector |
T682 | 2214-2223 | NNS | denotes | responses |
T683 | 2224-2226 | IN | denotes | on |
T684 | 2227-2232 | NN | denotes | offer |
T685 | 2233-2235 | IN | denotes | by |
T686 | 2236-2239 | DT | denotes | the |
T687 | 2240-2246 | JJ | denotes | immune |
T688 | 2247-2253 | NN | denotes | system |
T689 | 2255-2259 | JJ | denotes | Such |
T690 | 2260-2270 | NN | denotes | “next‐gen” |
T691 | 2271-2280 | NNS | denotes | biologics |
T692 | 2281-2285 | MD | denotes | will |
T693 | 2286-2291 | VB | denotes | begin |
T694 | 2292-2294 | TO | denotes | to |
T695 | 2295-2302 | VB | denotes | realize |
T696 | 2303-2306 | DT | denotes | the |
T697 | 2307-2311 | JJ | denotes | full |
T698 | 2312-2321 | NN | denotes | potential |
T699 | 2322-2324 | IN | denotes | of |
T700 | 2325-2338 | JJ | denotes | FcγR‐mediated |
T701 | 2339-2347 | NN | denotes | antibody |
T702 | 2348-2354 | JJ | denotes | immune |
T703 | 2355-2367 | NNS | denotes | therapeutics |
T704 | 2368-2371 | CC | denotes | and |
T705 | 2372-2377 | VB | denotes | offer |
T706 | 2378-2394 | JJ | denotes | transformational |
T707 | 2395-2401 | NN | denotes | change |
T708 | 2402-2405 | IN | denotes | for |
T709 | 2406-2409 | DT | denotes | the |
T710 | 2410-2419 | NN | denotes | treatment |
T711 | 2420-2422 | IN | denotes | of |
T712 | 2423-2434 | JJ | denotes | intractable |
T713 | 2435-2438 | CC | denotes | and |
T714 | 2439-2448 | JJ | denotes | incurable |
T715 | 2449-2457 | NNS | denotes | diseases |
R367 | T358 | T356 | arg1Of | Strategies,Future |
R368 | T358 | T357 | arg1Of | Strategies,Engineering |
R369 | T360 | T359 | arg1Of | antibodies,Monoclonal |
R370 | T360 | T361 | arg1Of | antibodies,are |
R371 | T363 | T361 | arg2Of | therapeutics,are |
R372 | T363 | T362 | arg1Of | therapeutics,potent |
R373 | T361 | T364 | arg1Of | are,in |
R374 | T366 | T364 | arg2Of | number,in |
R375 | T366 | T365 | arg1Of | number,a |
R376 | T366 | T367 | arg1Of | number,of |
R377 | T372 | T367 | arg2Of | diseases,of |
R378 | T372 | T368 | arg1Of | diseases,chronic |
R379 | T368 | T369 | arg1Of | chronic,or |
R380 | T371 | T369 | arg2Of | incurable,or |
R381 | T371 | T370 | arg1Of | incurable,once |
R382 | T372 | T371 | arg1Of | diseases,incurable |
R383 | T376 | T373 | arg1Of | is,However |
R384 | T376 | T374 | arg1Of | is,"," |
R385 | T375 | T376 | arg1Of | there,is |
R386 | T384 | T376 | arg2Of | as,is |
R387 | T376 | T377 | arg1Of | is,still |
R388 | T380 | T378 | arg1Of | clinical,extensive |
R389 | T380 | T379 | arg1Of | clinical,unmet |
R390 | T381 | T380 | arg1Of | need,clinical |
R391 | T384 | T382 | arg1Of | as,as |
R392 | T384 | T383 | arg1Of | as,well |
R393 | T381 | T384 | arg1Of | need,as |
R394 | T386 | T384 | arg2Of | room,as |
R395 | T386 | T385 | arg1Of | room,considerable |
R396 | T386 | T387 | arg1Of | room,for |
R397 | T388 | T387 | arg2Of | improvement,for |
R398 | T388 | T389 | arg1Of | improvement,in |
R399 | T392 | T389 | arg2Of | therapeutics,in |
R400 | T392 | T390 | arg1Of | therapeutics,many |
R401 | T392 | T391 | arg1Of | therapeutics,existing |
R402 | T394 | T393 | arg1Of | understanding,Further |
R403 | T394 | T395 | arg1Of | understanding,of |
R404 | T396 | T395 | arg2Of | how,of |
R405 | T399 | T396 | arg1Of | affects,how |
R406 | T398 | T397 | arg1Of | structure,antibody |
R407 | T398 | T399 | arg1Of | structure,affects |
R408 | T401 | T399 | arg2Of | function,affects |
R409 | T401 | T400 | arg1Of | function,FcγR |
R410 | T394 | T402 | arg1Of | understanding,is |
R411 | T403 | T402 | arg2Of | essential,is |
R412 | T394 | T403 | arg1Of | understanding,essential |
R413 | T403 | T404 | arg1Of | essential,for |
R414 | T406 | T404 | arg2Of | development,for |
R415 | T406 | T405 | arg1Of | development,future |
R416 | T406 | T407 | arg1Of | development,of |
R417 | T412 | T407 | arg2Of | mAbs,of |
R418 | T412 | T408 | arg1Of | mAbs,more |
R419 | T412 | T409 | arg1Of | mAbs,potent |
R420 | T409 | T410 | arg1Of | potent,and |
R421 | T411 | T410 | arg2Of | effective,and |
R422 | T412 | T411 | arg1Of | mAbs,effective |
R423 | T443 | T413 | arg1Of | and,Already |
R424 | T443 | T414 | arg1Of | and,"," |
R425 | T415 | T416 | arg1Of | engineering,of |
R426 | T420 | T416 | arg2Of | and,of |
R427 | T419 | T417 | arg1Of | Fc,the |
R428 | T419 | T418 | arg1Of | Fc,IgG |
R429 | T419 | T420 | arg1Of | Fc,and |
R430 | T422 | T420 | arg2Of | glycan,and |
R431 | T422 | T421 | arg1Of | glycan,its |
R432 | T415 | T423 | arg1Of | engineering,has |
R433 | T424 | T423 | arg2Of | proved,has |
R434 | T415 | T424 | arg1Of | engineering,proved |
R435 | T435 | T424 | arg2Of | ",",proved |
R436 | T429 | T425 | arg1Of | approach,a |
R437 | T429 | T426 | arg1Of | approach,potent |
R438 | T426 | T427 | arg1Of | potent,and |
R439 | T428 | T427 | arg2Of | effective,and |
R440 | T429 | T428 | arg1Of | approach,effective |
R441 | T429 | T430 | arg1Of | approach,for |
R442 | T431 | T430 | arg2Of | increasing,for |
R443 | T434 | T431 | arg2Of | effectiveness,increasing |
R444 | T434 | T432 | arg1Of | effectiveness,the |
R445 | T434 | T433 | arg1Of | effectiveness,clinical |
R446 | T429 | T435 | arg1Of | approach,"," |
R447 | T438 | T435 | arg2Of | and,"," |
R448 | T438 | T436 | arg1Of | and,functional |
R449 | T437 | T438 | arg1Of | specificity,and |
R450 | T439 | T438 | arg2Of | safety,and |
R451 | T438 | T440 | arg1Of | and,of |
R452 | T442 | T440 | arg2Of | mAbs,of |
R453 | T442 | T441 | arg1Of | mAbs,therapeutic |
R454 | T424 | T443 | arg1Of | proved,and |
R455 | T444 | T443 | arg2Of | is,and |
R456 | T415 | T444 | arg1Of | engineering,is |
R457 | T447 | T444 | arg2Of | pathway,is |
R458 | T447 | T445 | arg1Of | pathway,an |
R459 | T447 | T446 | arg1Of | pathway,emerging |
R460 | T447 | T448 | arg1Of | pathway,to |
R461 | T450 | T448 | arg2Of | development,to |
R462 | T450 | T449 | arg1Of | development,the |
R463 | T450 | T451 | arg1Of | development,of |
R464 | T454 | T451 | arg2Of | therapeutics,of |
R465 | T454 | T452 | arg1Of | therapeutics,the |
R466 | T454 | T453 | arg1Of | therapeutics,“next‐gen” |
R467 | T456 | T455 | arg1Of | directions,Future |
R468 | T456 | T457 | arg1Of | directions,in |
R469 | T460 | T457 | arg2Of | and,in |
R470 | T460 | T458 | arg1Of | and,the |
R471 | T459 | T460 | arg1Of | development,and |
R472 | T461 | T460 | arg2Of | use,and |
R473 | T460 | T462 | arg1Of | and,of |
R474 | T464 | T462 | arg2Of | antibodies,of |
R475 | T464 | T463 | arg1Of | antibodies,therapeutic |
R476 | T456 | T465 | arg1Of | directions,should |
R477 | T467 | T465 | arg2Of | mimic,should |
R478 | T467 | T466 | arg1Of | mimic,increasingly |
R479 | T456 | T467 | arg1Of | directions,mimic |
R480 | T471 | T467 | arg2Of | responses,mimic |
R481 | T471 | T468 | arg1Of | responses,normal |
R482 | T471 | T469 | arg1Of | responses,protective |
R483 | T471 | T470 | arg1Of | responses,antibody |
R484 | T471 | T472 | arg1Of | responses,"," |
R485 | T471 | T473 | arg1Of | responses,which |
R486 | T471 | T474 | arg1Of | responses,are |
R487 | T476 | T474 | arg2Of | and,are |
R488 | T471 | T475 | arg1Of | responses,polyclonal |
R489 | T475 | T476 | arg1Of | polyclonal,and |
R490 | T477 | T476 | arg2Of | elicited,and |
R491 | T471 | T477 | arg2Of | responses,elicited |
R492 | T477 | T478 | arg1Of | elicited,in |
R493 | T480 | T478 | arg2Of | context,in |
R494 | T480 | T479 | arg1Of | context,the |
R495 | T480 | T481 | arg1Of | context,of |
R496 | T484 | T481 | arg2Of | engagement,of |
R497 | T484 | T482 | arg1Of | engagement,innate |
R498 | T484 | T483 | arg1Of | engagement,receptor |
R499 | T480 | T485 | arg1Of | context,which |
R500 | T480 | T486 | arg1Of | context,includes |
R501 | T491 | T486 | arg2Of | as,includes |
R502 | T491 | T487 | arg1Of | as,the |
R503 | T491 | T489 | arg1Of | as,as |
R504 | T491 | T490 | arg1Of | as,well |
R505 | T488 | T491 | arg1Of | FcR,as |
R506 | T495 | T491 | arg2Of | systems,as |
R507 | T495 | T492 | arg1Of | systems,other |
R508 | T495 | T493 | arg1Of | systems,powerfully |
R509 | T495 | T494 | arg1Of | systems,responsive |
R510 | T495 | T496 | arg1Of | systems,including |
R511 | T500 | T496 | arg2Of | and,including |
R512 | T500 | T497 | arg1Of | and,the |
R513 | T499 | T498 | arg1Of | receptors,Toll‐like |
R514 | T499 | T500 | arg1Of | receptors,and |
R515 | T502 | T500 | arg2Of | receptors,and |
R516 | T502 | T501 | arg1Of | receptors,complement |
R517 | T514 | T503 | arg1Of | suggests,Furthermore |
R518 | T514 | T504 | arg1Of | suggests,"," |
R519 | T508 | T505 | arg1Of | nature,the |
R520 | T508 | T506 | arg1Of | nature,mixed |
R521 | T508 | T507 | arg1Of | nature,subclass |
R522 | T508 | T509 | arg1Of | nature,of |
R523 | T513 | T509 | arg2Of | responses,of |
R524 | T513 | T510 | arg1Of | responses,these |
R525 | T513 | T511 | arg1Of | responses,normal |
R526 | T513 | T512 | arg1Of | responses,antibody |
R527 | T508 | T514 | arg1Of | nature,suggests |
R528 | T518 | T514 | arg2Of | arise,suggests |
R529 | T518 | T515 | arg1Of | arise,that |
R530 | T516 | T517 | arg1Of | circumstances,may |
R531 | T518 | T517 | arg2Of | arise,may |
R532 | T516 | T518 | arg1Of | circumstances,arise |
R533 | T518 | T519 | arg1Of | arise,in |
R534 | T521 | T519 | arg2Of | strategies,in |
R535 | T521 | T520 | arg1Of | strategies,therapeutic |
R536 | T521 | T522 | arg1Of | strategies,where |
R537 | T524 | T522 | arg2Of | is,where |
R538 | T523 | T524 | arg1Of | there,is |
R539 | T525 | T524 | arg2Of | value,is |
R540 | T525 | T526 | arg1Of | value,in |
R541 | T527 | T526 | arg2Of | having,in |
R542 | T530 | T527 | arg2Of | Fcs,having |
R543 | T530 | T528 | arg1Of | Fcs,distinctly |
R544 | T530 | T529 | arg2Of | Fcs,modified |
R545 | T530 | T531 | arg1Of | Fcs,for |
R546 | T534 | T531 | arg2Of | engagement,for |
R547 | T534 | T532 | arg1Of | engagement,the |
R548 | T534 | T533 | arg1Of | engagement,nuanced |
R549 | T534 | T535 | arg1Of | engagement,of |
R550 | T539 | T535 | arg2Of | members,of |
R551 | T539 | T536 | arg1Of | members,different |
R552 | T539 | T537 | arg1Of | members,FcγR |
R553 | T539 | T538 | arg1Of | members,family |
R554 | T540 | T541 | arg1Of | Treatments,comprising |
R555 | T544 | T541 | arg2Of | and,comprising |
R556 | T543 | T542 | arg1Of | mAbs,multiple |
R557 | T543 | T544 | arg1Of | mAbs,and |
R558 | T546 | T544 | arg2Of | stimulants,and |
R559 | T546 | T545 | arg1Of | stimulants,immune |
R560 | T540 | T547 | arg1Of | Treatments,are |
R561 | T548 | T547 | arg2Of | under,are |
R562 | T540 | T548 | arg1Of | Treatments,under |
R563 | T549 | T548 | arg2Of | investigation,under |
R564 | T547 | T550 | arg1Of | are,in |
R565 | T552 | T550 | arg2Of | disease,in |
R566 | T552 | T551 | arg1Of | disease,infectious |
R567 | T552 | T553 | arg1Of | disease,for |
R568 | T555 | T553 | arg2Of | coverage,for |
R569 | T555 | T554 | arg1Of | coverage,neutralization |
R570 | T555 | T556 | arg1Of | coverage,of |
R571 | T558 | T556 | arg2Of | strains,of |
R572 | T558 | T557 | arg1Of | strains,variant |
R573 | T565 | T559 | arg1Of | be,Indeed |
R574 | T565 | T560 | arg1Of | be,"," |
R575 | T563 | T561 | arg1Of | approach,such |
R576 | T563 | T562 | arg1Of | approach,an |
R577 | T563 | T564 | arg1Of | approach,may |
R578 | T565 | T564 | arg2Of | be,may |
R579 | T563 | T565 | arg1Of | approach,be |
R580 | T567 | T565 | arg2Of | effective,be |
R581 | T567 | T566 | arg1Of | effective,most |
R582 | T563 | T567 | arg1Of | approach,effective |
R583 | T567 | T568 | arg1Of | effective,in |
R584 | T569 | T568 | arg2Of | emerging,in |
R585 | T571 | T569 | arg2Of | disease,emerging |
R586 | T571 | T570 | arg1Of | disease,infectious |
R587 | T573 | T572 | arg1Of | as,such |
R588 | T571 | T573 | arg1Of | disease,as |
R589 | T583 | T573 | arg2Of | infection,as |
R590 | T576 | T574 | arg1Of | respiratory,severe |
R591 | T576 | T575 | arg1Of | respiratory,acute |
R592 | T583 | T576 | arg1Of | infection,respiratory |
R593 | T583 | T577 | arg1Of | infection,syndrome |
R594 | T583 | T578 | arg1Of | infection,coronavirus |
R595 | T583 | T579 | arg1Of | infection,2 |
R596 | T583 | T580 | arg1Of | infection,( |
R597 | T581 | T580 | arg2Of | SARS‐CoV‐2,( |
R598 | T582 | T580 | arg3Of | ),( |
R599 | T585 | T584 | arg1Of | use,The |
R600 | T585 | T586 | arg1Of | use,of |
R601 | T588 | T586 | arg2Of | mAbs,of |
R602 | T588 | T587 | arg1Of | mAbs,multiple |
R603 | T588 | T589 | arg2Of | mAbs,tailored |
R604 | T589 | T590 | arg1Of | tailored,for |
R605 | T593 | T590 | arg2Of | functions,for |
R606 | T593 | T591 | arg1Of | functions,distinct |
R607 | T593 | T592 | arg1Of | functions,effector |
R608 | T589 | T594 | arg1Of | tailored,and |
R609 | T595 | T594 | arg2Of | targeting,and |
R610 | T588 | T595 | arg1Of | mAbs,targeting |
R611 | T597 | T595 | arg2Of | epitopes,targeting |
R612 | T597 | T596 | arg1Of | epitopes,different |
R613 | T585 | T598 | arg1Of | use,will |
R614 | T599 | T598 | arg2Of | maximize,will |
R615 | T585 | T599 | arg1Of | use,maximize |
R616 | T601 | T599 | arg2Of | opportunity,maximize |
R617 | T601 | T600 | arg1Of | opportunity,the |
R618 | T601 | T602 | arg1Of | opportunity,for |
R619 | T603 | T602 | arg2Of | cocktailing,for |
R620 | T603 | T604 | arg1Of | cocktailing,of |
R621 | T606 | T604 | arg2Of | functions,of |
R622 | T606 | T605 | arg1Of | functions,effector |
R623 | T599 | T607 | arg1Of | maximize,in |
R624 | T609 | T607 | arg2Of | types,in |
R625 | T609 | T608 | arg1Of | types,different |
R626 | T609 | T610 | arg1Of | types,of |
R627 | T611 | T610 | arg2Of | diseases,of |
R628 | T631 | T612 | arg1Of | uses,Indeed |
R629 | T631 | T613 | arg1Of | uses,"," |
R630 | T631 | T614 | arg1Of | uses,in |
R631 | T619 | T614 | arg2Of | example,in |
R632 | T619 | T615 | arg1Of | example,a |
R633 | T619 | T616 | arg1Of | example,small |
R634 | T616 | T617 | arg1Of | small,but |
R635 | T618 | T617 | arg2Of | contemporary,but |
R636 | T619 | T618 | arg1Of | example,contemporary |
R637 | T619 | T620 | arg1Of | example,outside |
R638 | T620 | T621 | arg1Of | outside,of |
R639 | T623 | T621 | arg2Of | disease,of |
R640 | T623 | T622 | arg1Of | disease,infectious |
R641 | T631 | T624 | arg1Of | uses,"," |
R642 | T627 | T625 | arg1Of | combination,the |
R643 | T627 | T626 | arg1Of | combination,FDA‐approved |
R644 | T627 | T628 | arg1Of | combination,in |
R645 | T630 | T628 | arg2Of | therapy,in |
R646 | T630 | T629 | arg1Of | therapy,adenocarcinoma |
R647 | T627 | T631 | arg1Of | combination,uses |
R648 | T633 | T631 | arg2Of | cocktail,uses |
R649 | T633 | T632 | arg1Of | cocktail,a |
R650 | T633 | T634 | arg1Of | cocktail,of |
R651 | T636 | T634 | arg2Of | mAbs,of |
R652 | T636 | T635 | arg1Of | mAbs,two |
R653 | T633 | T637 | arg1Of | cocktail,"," |
R654 | T639 | T637 | arg2Of | and,"," |
R655 | T638 | T639 | arg1Of | pertuzumab,and |
R656 | T640 | T639 | arg2Of | trastuzumab,and |
R657 | T631 | T641 | arg1Of | uses,"," |
R658 | T631 | T642 | arg1Of | uses,against |
R659 | T643 | T642 | arg2Of | Her2.123,against |
R660 | T674 | T644 | arg1Of | utilize,Rather |
R661 | T644 | T645 | arg1Of | Rather,than |
R662 | T647 | T645 | arg2Of | type,than |
R663 | T647 | T646 | arg1Of | type,one |
R664 | T647 | T648 | arg1Of | type,of |
R665 | T649 | T648 | arg2Of | Fc,of |
R666 | T651 | T650 | arg1Of | conquer,to |
R667 | T647 | T650 | modOf | type,to |
R668 | T652 | T651 | arg2Of | all,conquer |
R669 | T674 | T653 | arg1Of | utilize,"," |
R670 | T656 | T654 | arg1Of | use,the |
R671 | T656 | T655 | arg1Of | use,combined |
R672 | T656 | T657 | arg1Of | use,of |
R673 | T660 | T657 | arg2Of | mAbs,of |
R674 | T659 | T658 | arg1Of | selected,appropriately |
R675 | T660 | T659 | arg1Of | mAbs,selected |
R676 | T663 | T661 | arg1Of | components,whose |
R677 | T660 | T661 | arg2Of | mAbs,whose |
R678 | T663 | T662 | arg1Of | components,individual |
R679 | T663 | T664 | arg1Of | components,are |
R680 | T665 | T664 | arg2Of | enhanced,are |
R681 | T663 | T665 | arg2Of | components,enhanced |
R682 | T665 | T666 | arg1Of | enhanced,for |
R683 | T668 | T666 | arg2Of | engagement,for |
R684 | T668 | T667 | arg1Of | engagement,the |
R685 | T668 | T669 | arg1Of | engagement,of |
R686 | T672 | T669 | arg2Of | members,of |
R687 | T672 | T670 | arg1Of | members,different |
R688 | T672 | T671 | arg1Of | members,FcγR |
R689 | T656 | T673 | arg1Of | use,may |
R690 | T674 | T673 | arg2Of | utilize,may |
R691 | T656 | T674 | arg1Of | use,utilize |
R692 | T676 | T674 | arg2Of | components,utilize |
R693 | T676 | T675 | arg1Of | components,multiple |
R694 | T676 | T677 | arg1Of | components,of |
R695 | T679 | T677 | arg2Of | spectrum,of |
R696 | T679 | T678 | arg1Of | spectrum,the |
R697 | T679 | T680 | arg1Of | spectrum,of |
R698 | T682 | T680 | arg2Of | responses,of |
R699 | T682 | T681 | arg1Of | responses,effector |
R700 | T679 | T683 | arg1Of | spectrum,on |
R701 | T684 | T683 | arg2Of | offer,on |
R702 | T674 | T685 | arg1Of | utilize,by |
R703 | T688 | T685 | arg2Of | system,by |
R704 | T688 | T686 | arg1Of | system,the |
R705 | T688 | T687 | arg1Of | system,immune |
R706 | T691 | T689 | arg1Of | biologics,Such |
R707 | T691 | T690 | arg1Of | biologics,“next‐gen” |
R708 | T691 | T692 | arg1Of | biologics,will |
R709 | T693 | T692 | arg2Of | begin,will |
R710 | T691 | T693 | arg1Of | biologics,begin |
R711 | T704 | T693 | arg2Of | and,begin |
R712 | T704 | T694 | arg1Of | and,to |
R713 | T691 | T695 | arg1Of | biologics,realize |
R714 | T698 | T695 | arg2Of | potential,realize |
R715 | T698 | T696 | arg1Of | potential,the |
R716 | T698 | T697 | arg1Of | potential,full |
R717 | T698 | T699 | arg1Of | potential,of |
R718 | T703 | T699 | arg2Of | therapeutics,of |
R719 | T703 | T700 | arg1Of | therapeutics,FcγR‐mediated |
R720 | T703 | T701 | arg1Of | therapeutics,antibody |
R721 | T703 | T702 | arg1Of | therapeutics,immune |
R722 | T695 | T704 | arg1Of | realize,and |
R723 | T705 | T704 | arg2Of | offer,and |
R724 | T691 | T705 | arg1Of | biologics,offer |
R725 | T707 | T705 | arg2Of | change,offer |
R726 | T707 | T706 | arg1Of | change,transformational |
R727 | T705 | T708 | arg1Of | offer,for |
R728 | T710 | T708 | arg2Of | treatment,for |
R729 | T710 | T709 | arg1Of | treatment,the |
R730 | T710 | T711 | arg1Of | treatment,of |
R731 | T715 | T711 | arg2Of | diseases,of |
R732 | T715 | T712 | arg1Of | diseases,intractable |
R733 | T712 | T713 | arg1Of | intractable,and |
R734 | T714 | T713 | arg2Of | incurable,and |
R735 | T715 | T714 | arg1Of | diseases,incurable |