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Id Subject Object Predicate Lexical cue ForCovid19 Memo all_replicate tao:has_database_id
T63 0-18 NegativeRegulation denotes Counter-regulatory t
T25 19-45 Phenomena denotes 'Renin-Angiotensin' System MESH:D012084
T26 62-67 Chemical denotes Drugs drug MESH:D008511
T91 71-76 Therapy denotes Treat
T10 77-85 Disease denotes COVID-19 MESH:D000086382
T1 98-108 Species denotes SARS-CoV-2 t Tax:2697049
T28 109-117 Disease denotes infected t MESH:D007239
T31 118-126 Species denotes patients Tax:9606
T2 128-138 Species denotes SARS-CoV-2 Tax:2697049
T11 141-149 Disease denotes COVID-19 MESH:D000086382
T34 158-184 Phenomena denotes 'Renin-Angiotensin' System MESH:D012084
T62 200-226 Phenomena denotes 'Renin-Angiotensin' system MESH:D012084
T37 228-231 Phenomena denotes RAS MESH:D012084
T65 254-292 Phenomena denotes 'Renin-Angiotensin-Aldosterone' system MESH:D012084
T81 332-338 Species denotes humans Tax:9606
T67 367-372 Anatomy denotes renal MESH:D007668
T70 374-388 Anatomy denotes cardiovascular MESH:D002319
T71 393-406 Phenomena denotes innate immune MESH:D007113
T89 459-468 Chemical denotes vitamin D MESH:D014807
T82 523-542 NegativeRegulation denotes negative regulatory
T38 557-560 Phenomena denotes RAS MESH:D012084
T92 588-603 PositiveRegulation denotes over-reactivity
T39 608-611 Phenomena denotes RAS MESH:D012084
T94 627-644 Disease denotes hypovitaminosis D MESH:D014808
T68 692-697 Anatomy denotes renal MESH:D007668
T83 699-706 Anatomy denotes cardiac MESH:D002319
T84 708-716 Anatomy denotes vascular MESH:D002319
T86 721-727 Phenomena denotes immune MESH:D007109
T12 763-771 Disease denotes COVID-19 t MESH:D000086382
T32 772-780 Species denotes patients Tax:9606
T87 796-810 Disease denotes cytokine storm MESH:D000080424
T131 839-845 Phenomena denotes immune MESH:D007109
T97 936-942 Condition denotes lethal
T96 943-978 Disease denotes acute respiratory distress syndrome MESH:D012128
T3 997-1007 Species denotes SARS-CoV-2 Tax:2697049
T13 1039-1047 Disease denotes COVID-19 MESH:D000086382
T123 1071-1080 PositiveRegulation denotes interfere
T40 1090-1093 Phenomena denotes RAS MESH:D012084
T100 1101-1112 Phenomena denotes interacting MESH:D053585
T98 1122-1144 Gene denotes spike (S) glycoprotein Gene:43740568
T110 1172-1203 Gene denotes Angiotensin-Converting Enzyme 2 Gene:59272
T101 1205-1209 Gene denotes ACE2 Gene:59272
T111 1236-1245 Localization denotes expressed
T113 1264-1280 Anatomy denotes epithelial cells MESH:D004847
T114 1286-1299 Anatomy denotes blood vessels MESH:D001808
T115 1301-1305 Anatomy denotes lung MESH:D008168
T119 1307-1313 Anatomy denotes kidney MESH:D007668
T69 1315-1328 Anatomy denotes renal tubules MESH:D007684
T124 1331-1340 Anatomy denotes intestine MESH:D007422
T118 1346-1351 Anatomy denotes heart MESH:D006321
T302 1367-1375 Anatomy denotes cerebral MESH:D001921
T125 1376-1383 Anatomy denotes neurons MESH:D009474
T128 1388-1394 Anatomy denotes immune MESH:D008264
T133 1388-1404 Anatomy denotes immune monocytes MESH:D009000
T126 1405-1416 Anatomy denotes macrophages MESH:D008264
T4 1435-1445 Species denotes SARS-CoV-2 Tax:2697049
T14 1454-1462 Disease denotes COVID-19 MESH:D000086382
T134 1503-1515 Disease denotes hypertension MESH:D006973
T135 1517-1532 Disease denotes atherosclerosis MESH:D050197
T136 1534-1544 Disease denotes thrombosis MESH:D013927
T137 1546-1558 Disease denotes coagulopathy MESH:D001778
T138 1561-1569 Disease denotes diarrhea MESH:D003967
T139 1571-1579 Disease denotes glaucoma MESH:D005901
T140 1581-1588 Disease denotes anosmia MESH:D000857
T141 1590-1597 Disease denotes ageusia MESH:D000370
T142 1599-1611 Disease denotes skin lesions MESH:D012871
T143 1613-1623 Disease denotes dermatitis MESH:D003872
T144 1626-1679 Disease denotes autoimmune inflammation of the central nervous system MESH:D020278
T145 1685-1692 Disease denotes damages
T116 1723-1727 Anatomy denotes lung MESH:D008168
T117 1729-1734 Anatomy denotes heart MESH:D006321
T120 1736-1742 Anatomy denotes kidney MESH:D007668
T146 1748-1756 Anatomy denotes testicle MESH:D013737
T315 1773-1778 Disease denotes these
T147 1779-1786 Condition denotes diffuse
T15 1787-1795 Disease denotes COVID-19 MESH:D000086382
T148 1830-1843 PositiveRegulation denotes over-reaction
T41 1847-1850 Phenomena denotes RAS MESH:D012084
T5 1854-1864 Species denotes SARS-CoV-2 t Tax:2697049
T29 1865-1873 Disease denotes infected t MESH:D007239
T30 1874-1881 Species denotes persons Tax:9606
T42 1890-1893 Phenomena denotes RAS MESH:D012084
T149 1894-1903 PositiveRegulation denotes imbalance
T95 1929-1946 Disease denotes hypovitaminosis D MESH:D014808
T43 1964-1967 Phenomena denotes RAS MESH:D012084
T16 1993-2001 Disease denotes COVID-19 MESH:D000086382
T44 2106-2109 Phenomena denotes RAS MESH:D012084
T17 2131-2139 Disease denotes COVID-19 MESH:D000086382
T35 2151-2177 Phenomena denotes 'Renin-Angiotensin' System MESH:D012084
T36 2179-2182 Phenomena denotes RAS MESH:D012084
T64 2186-2204 NegativeRegulation denotes Counter-regulatory
T45 2205-2208 Phenomena denotes RAS MESH:D012084
T46 2216-2219 Phenomena denotes RAS MESH:D012084
T150 2237-2242 Gene denotes Renin Gene:5972
T121 2244-2250 Anatomy denotes kidney MESH:D007668
T170 2252-2259 PositiveRegulation denotes cleaves
T151 2260-2275 Gene denotes Angiotensinogen Gene:183
T122 2277-2282 Anatomy denotes liver MESH:D008099
T152 2292-2305 Biological denotes Angiotensin I MESH:D000803
T166 2320-2330 Biological denotes DRVYIHPFHL MESH:D010455
T184 2337-2343 Biological denotes latter MESH:D000803
T185 2347-2354 PositiveRegulation denotes cleaved
T173 2362-2391 Gene denotes Angiotensin-Converting Enzyme Gene:1636
T174 2393-2396 Gene denotes ACE Gene:1636
T153 2409-2423 Gene denotes Angiotensin II MESH:D000804
T167 2438-2446 Biological denotes DRVYIHPF MESH:D010455
T102 2475-2479 Gene denotes ACE2 Gene:59272
T6 2481-2500 Gene denotes SARS-CoV-2 receptor Gene:59272
T47 2524-2527 Phenomena denotes RAS MESH:D012084
T196 2542-2549 Phenomena denotes targets MESH:D011485
T154 2553-2567 Biological denotes Angiotensin II MESH:D000804
T326 2576-2591 Phenomena denotes vasoconstrictor MESH:D014661
T214 2592-2598 Gene denotes type 1 Gene:185
T198 2600-2604 Gene denotes AT1R Gene:185
T321 2610-2623 Phenomena denotes vasodilatator MESH:D014664
T217 2624-2630 Gene denotes type 2 Gene:186
T202 2632-2636 Gene denotes AT2R Gene:186
T216 2638-2661 Gene denotes Angiotensin II receptor Gene:186
T155 2638-2661 Gene denotes Angiotensin II receptor Gene:185
T199 2664-2668 Gene denotes AT1R Gene:185
T112 2672-2681 Localization denotes expressed
T218 2700-2709 Anatomy denotes monocytes MESH:D009000
T127 2710-2721 Anatomy denotes macrophages MESH:D008264
T219 2726-2733 Anatomy denotes T-cells MESH:D013601
T48 2750-2753 Phenomena denotes RAS MESH:D012084
T319 2754-2758 PositiveRegulation denotes acts
T320 2762-2777 Phenomena denotes innate immunity MESH:D007113
T186 2793-2800 PositiveRegulation denotes cleaved
T103 2804-2808 Gene denotes ACE2 Gene:59272
T156 2810-2824 Biological denotes Angiotensin II MESH:D000804
T190 2831-2846 Biological denotes Angiotensin 1-7 MESH:C118790
T195 2861-2868 Biological denotes DRVYIHP MESH:D010455
T221 2871-2880 Phenomena denotes targeting MESH:D011485
T322 2885-2898 Phenomena denotes vasodilatator MESH:D014664
T327 2899-2926 Gene denotes proto-oncogene Mas receptor Gene:116511
T220 2928-2932 Gene denotes MasR Gene:116511
T191 2935-2950 Biological denotes Angiotensin 1-7 MESH:C118790
T223 2966-2977 PositiveRegulation denotes transformed
T222 2981-2991 Biological denotes Alamandine MESH:C581752
T213 3006-3013 Biological denotes ARVYIHP MESH:D010455
T224 3021-3044 Gene denotes aspartate decarboxylase MESH:C019747
T228 3046-3056 Biological denotes Alamandine MESH:C581752
T229 3063-3067 Phenomena denotes bind MESH:D011485
T323 3075-3088 Phenomena denotes vasodilatator MESH:D014664
T225 3089-3136 Gene denotes Mas-related G protein-coupled receptor member D Gene:116512
T226 3138-3142 Gene denotes MRGD Gene:116512
T192 3171-3186 Biological denotes Angiotensin 1-7 MESH:C118790
T157 3201-3215 Biological denotes Angiotensin II MESH:D000804
T231 3220-3227 PositiveRegulation denotes produce
T328 3228-3241 Biological denotes Angiotensin A MESH:C516880
T230 3228-3241 Biological denotes Angiotensin A MESH:C516880
T329 3256-3264 Biological denotes ARVYIHPF MESH:D010455
T209 3256-3264 Biological denotes ARVYIHPF MESH:D010455
T232 3273-3296 Gene denotes aspartate decarboxylase MESH:C019747
T234 3302-3312 Biological denotes Alamandine MESH:C581752
T104 3331-3335 Gene denotes ACE2 Gene:59272
T233 3336-3344 PositiveRegulation denotes cleavage
T105 3346-3350 Gene denotes ACE2 Gene:59272
T236 3360-3366 PositiveRegulation denotes cleave
T158 3367-3380 Biological denotes Angiotensin I MESH:D000803
T235 3389-3404 Biological denotes Angiotensin 1-9 MESH:C506331
T169 3419-3428 Biological denotes DRVYIHPFH MESH:D010455
T197 3437-3444 Phenomena denotes targets MESH:D011485
T203 3445-3449 Gene denotes AT2R Gene:186
T49 3458-3461 Phenomena denotes RAS MESH:D012084
T159 3505-3520 Biological denotes Angiotensin III MESH:D000805
T206 3535-3542 Biological denotes RVYIHPF MESH:D010455
T160 3548-3562 Biological denotes Angiotensin IV MESH:C022929
T210 3577-3583 Biological denotes VYIHPF MESH:D010455
T239 3594-3603 Phenomena denotes targeting MESH:D011485
T237 3594-3603 Phenomena denotes targeting MESH:D011485
T200 3608-3612 Gene denotes AT1R Gene:185
T324 3617-3630 Phenomena denotes vasodilatator MESH:D014664
T238 3631-3635 Gene denotes AT4R alternative short name: IRAP Gene:4012
T50 3695-3698 Phenomena denotes RAS MESH:D012084
T247 3700-3711 Biological denotes Angiotensin MESH:D000804
T243 3700-3711 Biological denotes Angiotensin MESH:D000803
T241 3713-3714 Biological denotes I MESH:D000803
T245 3719-3721 Biological denotes II MESH:D000804
T161 3729-3744 Biological denotes Angiotensin III MESH:D000805
T51 3791-3794 Phenomena denotes RAS MESH:D012084
T18 3833-3841 Disease denotes COVID-19 MESH:D000086382
T78 3884-3904 NegativeRegulation denotes 'counter-regulatory'
T52 3905-3908 Phenomena denotes RAS MESH:D012084
T262 3939-3950 Phenomena denotes homeostasis MESH:D006706
T193 3965-3980 Biological denotes Angiotensin 1-7 MESH:C118790
T248 3982-3997 Biological denotes Angiotensin 1-9 MESH:C506331
T251 3999-4009 Biological denotes Alamandine MESH:C581752
T252 4011-4024 Biological denotes Angiotensin A MESH:C516880
T162 4030-4044 Biological denotes Angiotensin IV MESH:C022929
T261 4056-4065 Phenomena denotes targeting MESH:D011485
T260 4056-4065 Phenomena denotes targeting MESH:D011485
T259 4056-4065 Phenomena denotes targeting MESH:D011485
T258 4056-4065 Phenomena denotes targeting MESH:D011485
T254 4056-4065 Phenomena denotes targeting MESH:D011485
T255 4070-4074 Gene denotes MasR Gene:116511
T204 4076-4080 Gene denotes AT2R Gene:186
T256 4082-4086 Gene denotes MRGD Gene:116512
T106 4088-4092 Gene denotes ACE2 Gene:59272
T257 4097-4101 Gene denotes AT4R alternative short name: IRAP Gene:4012
T325 4102-4115 Phenomena denotes vasodilatator MESH:D014664
T263 4141-4155 Biological denotes These peptides MESH:D010455
T264 4178-4194 Phenomena denotes cardioprotective
T265 4196-4206 Phenomena denotes vasoactive
T266 4208-4225 Phenomena denotes anti-hypertensive
T267 4228-4245 Phenomena denotes anti-hypertrophic
T268 4253-4270 Phenomena denotes anti-inflammatory
T189 4288-4321 Biological denotes Such naturally-produced molecules MESH:D010455
T53 4329-4332 Phenomena denotes RAS MESH:D012084
T269 4349-4359 NegativeRegulation denotes counteract
T7 4364-4374 Species denotes SARS-CoV-2 Tax:2697049
T270 4383-4398 PositiveRegulation denotes over-activation
T54 4402-4405 Phenomena denotes RAS MESH:D012084
T271 4410-4417 NegativeRegulation denotes reverse
T19 4450-4458 Disease denotes COVID-19 MESH:D000086382
T55 4518-4532 Chemical denotes RAS inhibitors drug
T20 4593-4601 Disease denotes COVID-19 MESH:D000086382
T33 4602-4610 Species denotes patients Tax:9606
T56 4632-4644 Chemical denotes RAS blockers drug
T21 4668-4676 Disease denotes COVID-19 MESH:D000086382
T57 4711-4725 Chemical denotes RAS inhibitors drug
T316 4733-4740 Inhibition denotes prevent
T88 4745-4759 Disease denotes cytokine storm MESH:D000080424
T58 4763-4766 Phenomena denotes RAS MESH:D012084
T274 4794-4801 PositiveRegulation denotes release
T318 4805-4821 Type denotes pro-inflammatory
T273 4822-4831 Biological denotes cytokines MESH:D016207
T22 4856-4864 Disease denotes COVID-19 MESH:D000086382
T8 4878-4888 Species denotes SARS-CoV-2 Tax:2697049
T27 4889-4897 Disease denotes infected MESH:D007239
T80 4898-4904 Species denotes humans Tax:9606
T59 4919-4922 Phenomena denotes RAS MESH:D012084
T276 4923-4935 PositiveRegulation denotes over-reacted
T107 4944-4948 Gene denotes ACE2 Gene:59272
T277 4960-4965 Species denotes viral Tax:2697049
T279 4966-4975 Disease denotes infection MESH:D007239
T90 4980-5000 Disease denotes vitamin D deficiency http://purl.obolibrary.org/obo/HP_0100512
T23 5027-5035 Disease denotes COVID-19 MESH:D000086382
T60 5065-5068 Phenomena denotes RAS MESH:D012084
T280 5094-5116 Chemical denotes chemotherapeutic drugs drug
T289 5122-5140 Chemical denotes proposed molecules
T182 5154-5168 Chemical denotes ACE inhibitors drug
T282 5173-5180 Inhibition denotes prevent
T281 5185-5195 PositiveRegulation denotes production
T163 5199-5213 Biological denotes Angiotensin II MESH:D000804
T164 5219-5232 Biological denotes Angiotensin I MESH:D000803
T283 5239-5247 Chemical denotes blockers drug
T284 5248-5259 Chemical denotes antagonists drug
T201 5263-5267 Gene denotes AT1R Gene:185
T286 5276-5284 Chemical denotes Losartan drug
T285 5276-5284 Chemical denotes Losartan drug MESH:D019808
T288 5289-5300 Chemical denotes derivatives drug
T290 5302-5313 Type denotes Recombinant MESH:D011994
T108 5314-5318 Gene denotes ACE2 Gene:59272
T292 5397-5408 NegativeRegulation denotes competitive
T291 5409-5416 Phenomena denotes binding MESH:D011485
T99 5424-5446 Gene denotes spike (S) glycoprotein Gene:43740568
T9 5450-5460 Species denotes SARS-CoV-2 Tax:2697049
T293 5510-5523 Chemical denotes peptide drugs drug MESH:D010455
T79 5543-5563 NegativeRegulation denotes 'counter-regulatory'
T61 5564-5567 Phenomena denotes RAS MESH:D012084
T194 5574-5589 Biological denotes Angiotensin 1-7 MESH:C118790
T249 5591-5606 Biological denotes Angiotensin 1-9 MESH:C506331
T250 5608-5618 Biological denotes Alamandine MESH:C581752
T253 5620-5633 Biological denotes Angiotensin A MESH:C516880
T165 5641-5655 Biological denotes Angiotensin IV MESH:C022929
T24 5665-5673 Disease denotes COVID-19 MESH:D000086382
T301 5689-5697 Phenomena denotes targeted MESH:D011485
T300 5689-5697 Phenomena denotes targeted MESH:D011485
T299 5689-5697 Phenomena denotes targeted MESH:D011485
T298 5689-5697 Phenomena denotes targeted MESH:D011485
T297 5689-5697 Phenomena denotes targeted MESH:D011485
T294 5722-5726 Gene denotes MasR Gene:116511
T205 5728-5732 Gene denotes AT2R Gene:186
T295 5734-5738 Gene denotes MRGD Gene:116512
T109 5740-5744 Gene denotes ACE2 Gene:59272
T296 5749-5753 Gene denotes AT4R alternative short name: IRAP Gene:4012
R100 T184 T152 coreference latter,Angiotensin I
R101 T184 T185 is_a latter,cleaved
R102 T151 T170 is_a Angiotensinogen,cleaves
R103 T170 T152 is_a cleaves,Angiotensin I
R104 T170 T166 is_a cleaves,DRVYIHPFHL
R105 T185 T153 is_a cleaved,Angiotensin II
R106 T185 T167 is_a cleaved,DRVYIHPF
R107 T173 T185 using Angiotensin-Converting Enzyme,cleaved
R108 T156 T186 is_a Angiotensin II,cleaved
R109 T186 T190 is_a cleaved,Angiotensin 1-7
R110 T103 T186 using ACE2,cleaved
R111 T186 T195 is_a cleaved,DRVYIHP
R112 T214 T155 - type 1,Angiotensin II receptor
R113 T217 T216 - type 2,Angiotensin II receptor
R115 T196 T214 to targets,type 1
R116 T196 T217 to targets,type 2
R117 T198 T214 abbreviation AT1R,type 1
R118 T202 T217 abbreviation AT2R,type 2
R119 T199 T112 is_a AT1R,expressed
R123 T190 T221 is_a Angiotensin 1-7,targeting
R125 T191 T223 is_a Angiotensin 1-7,transformed
R126 T223 T222 is_a transformed,Alamandine
R127 T223 T213 is_a transformed,ARVYIHP
R128 T224 T223 using aspartate decarboxylase,transformed
R129 T226 T225 abbreviation MRGD,Mas-related G protein-coupled receptor member D
R131 T229 T225 to bind,Mas-related G protein-coupled receptor member D
R132 T157 T231 is_a Angiotensin II,produce
R133 T231 T230 is_a produce,Angiotensin A
R134 T231 T209 is_a produce,ARVYIHPF
R135 T232 T231 using aspartate decarboxylase,produce
R137 T233 T234 is_a cleavage,Alamandine
R139 T158 T236 is_a Angiotensin I,cleave
R14 T5 T29 cause_of SARS-CoV-2,infected
R140 T236 T235 is_a cleave,Angiotensin 1-9
R141 T105 T236 using ACE2,cleave
R142 T236 T169 is_a cleave,DRVYIHPFH
R143 T235 T197 is_a Angiotensin 1-9,targets
R145 T159 T237 is_a Angiotensin III,targeting
R146 T206 T237 is_a RVYIHPF,targeting
R147 T237 T200 to targeting,AT1R
R148 T160 T239 is_a Angiotensin IV,targeting
R149 T210 T239 is_a VYIHPF,targeting
R150 T239 T238 to targeting,AT4R
R151 T243 T241 - Angiotensin,I
R152 T247 T245 - Angiotensin,II
R153 T193 T254 is_a Angiotensin 1-7,targeting
R154 T254 T255 to targeting,MasR
R155 T197 T203 to targets,AT2R
R156 T248 T258 is_a Angiotensin 1-9,targeting
R157 T258 T204 to targeting,AT2R
R158 T251 T259 is_a Alamandine,targeting
R159 T259 T256 to targeting,MRGD
R16 T64 T45 is_a Counter-regulatory,RAS
R160 T252 T260 is_a Angiotensin A,targeting
R161 T260 T106 to targeting,ACE2
R162 T162 T261 is_a Angiotensin IV,targeting
R163 T261 T257 to targeting,AT4R
R164 T263 T193 coreference These peptides,Angiotensin 1-7
R165 T263 T248 coreference These peptides,Angiotensin 1-9
R166 T263 T251 coreference These peptides,Alamandine
R167 T263 T252 coreference These peptides,Angiotensin A
R168 T263 T162 coreference These peptides,Angiotensin IV
R169 T263 T264 is_a These peptides,cardioprotective
R17 T78 T52 is_a 'counter-regulatory',RAS
R170 T263 T265 is_a These peptides,vasoactive
R171 T263 T266 is_a These peptides,anti-hypertensive
R172 T263 T267 is_a These peptides,anti-hypertrophic
R173 T263 T268 is_a These peptides,anti-inflammatory
R175 T189 T263 coreference Such naturally-produced molecules,These peptides
R176 T189 T269 is_a Such naturally-produced molecules,counteract
R177 T269 T270 is_a counteract,over-activation
R178 T270 T54 is_a over-activation,RAS
R179 T53 T189 of_a RAS,Such naturally-produced molecules
R180 T189 T271 is_a Such naturally-produced molecules,reverse
R181 T7 T270 cause_of SARS-CoV-2,over-activation
R184 T274 T273 is_a release,cytokines
R185 T274 T88 cause_of release,cytokine storm
R186 T277 T279 cause_of viral,infection
R187 T277 T8 coreference viral,SARS-CoV-2
R188 T279 T276 is_a infection,over-reacted
R189 T90 T276 is_a vitamin D deficiency,over-reacted
R19 T8 T27 cause_of SARS-CoV-2,infected
R190 T276 T59 is_a over-reacted,RAS
R191 T276 T22 cause_of over-reacted,COVID-19
R192 T107 T279 via ACE2,infection
R193 T164 T281 is_a Angiotensin I,production
R194 T281 T163 is_a production,Angiotensin II
R195 T282 T281 against prevent,production
R196 T182 T282 has_role ACE inhibitors,prevent
R197 T286 T288 - Losartan,derivatives
R198 T289 T280 coreference proposed molecules,chemotherapeutic drugs
R206 T290 T108 of_a Recombinant,ACE2
R21 T79 T61 is_a 'counter-regulatory',RAS
R210 T9 T99 of_a SARS-CoV-2,spike (S) glycoprotein
R217 T194 T297 is_a Angiotensin 1-7,targeted
R218 T297 T294 to targeted,MasR
R219 T249 T298 is_a Angiotensin 1-9,targeted
R220 T298 T205 to targeted,AT2R
R221 T250 T299 is_a Alamandine,targeted
R222 T299 T295 to targeted,MRGD
R223 T253 T300 is_a Angiotensin A,targeted
R224 T300 T109 to targeted,ACE2
R225 T301 T296 to targeted,AT4R
R226 T165 T301 is_a Angiotensin IV,targeted
R227 T302 T125 in cerebral,neurons
R238 T3 T98 of_a SARS-CoV-2,spike (S) glycoprotein
R242 T315 T134 coreference these,hypertension
R243 T315 T135 coreference these,atherosclerosis
R244 T315 T136 coreference these,thrombosis
R245 T315 T137 coreference these,coagulopathy
R246 T315 T138 coreference these,diarrhea
R247 T315 T139 coreference these,glaucoma
R248 T315 T140 coreference these,anosmia
R249 T315 T141 coreference these,ageusia
R25 T26 T91 using Drugs,Treat
R250 T315 T142 coreference these,skin lesions
R251 T315 T143 coreference these,dermatitis
R252 T315 T144 coreference these,autoimmune inflammation of the central nervous system
R253 T315 T145 coreference these,damages
R254 T58 T274 is_a RAS,release
R255 T57 T316 has_role RAS inhibitors,prevent
R257 T316 T274 against prevent,release
R258 T110 T111 is_a Angiotensin-Converting Enzyme 2,expressed
R259 T318 T273 of_a pro-inflammatory,cytokines
R261 T290 T292 is_a Recombinant,competitive
R262 T292 T291 is_a competitive,binding
R263 T291 T108 to binding,ACE2
R264 T99 T291 is_a spike (S) glycoprotein,binding
R265 T48 T319 is_a RAS,acts
R266 T319 T320 is_a acts,innate immunity
R267 T217 T321 is_a type 2,vasodilatator
R269 T225 T323 is_a Mas-related G protein-coupled receptor member D,vasodilatator
R270 T238 T324 is_a AT4R,vasodilatator
R271 T214 T326 is_a type 1,vasoconstrictor
R272 T255 T325 is_a MasR,vasodilatator
R273 T204 T325 is_a AT2R,vasodilatator
R274 T256 T325 is_a MRGD,vasodilatator
R275 T257 T325 is_a AT4R,vasodilatator
R276 T220 T327 abbreviation MasR,proto-oncogene Mas receptor
R277 T327 T322 is_a proto-oncogene Mas receptor,vasodilatator
R278 T221 T327 to targeting,proto-oncogene Mas receptor
R279 T104 T233 using ACE2,cleavage
R28 T89 T82 is_a vitamin D,negative regulatory
R280 T271 T19 is_a reverse,COVID-19
R281 T26 T25 for Drugs,'Renin-Angiotensin' System
R282 T91 T10 for Treat,COVID-19
R283 T31 T10 has_a patients,COVID-19
R284 T31 T28 has_a patients,infected
R285 T32 T12 has_a patients,COVID-19
R286 T32 T87 has_a patients,cytokine storm
R287 T32 T96 has_a patients,acute respiratory distress syndrome
R288 T111 T113 on expressed,epithelial cells
R289 T111 T125 on expressed,neurons
R29 T82 T38 is_a negative regulatory,RAS
R290 T111 T133 on expressed,immune monocytes
R291 T111 T128 on expressed,immune
R292 T14 T136 is_a COVID-19,thrombosis
R293 T14 T135 is_a COVID-19,atherosclerosis
R294 T14 T134 is_a COVID-19,hypertension
R295 T14 T143 is_a COVID-19,dermatitis
R296 T14 T142 is_a COVID-19,skin lesions
R297 T14 T141 is_a COVID-19,ageusia
R298 T14 T139 is_a COVID-19,glaucoma
R299 T14 T138 is_a COVID-19,diarrhea
R3 T1 T28 cause_of SARS-CoV-2,infected
R300 T14 T137 is_a COVID-19,coagulopathy
R301 T14 T140 is_a COVID-19,anosmia
R302 T14 T144 is_a COVID-19,autoimmune inflammation of the central nervous system
R303 T14 T145 is_a COVID-19,damages
R304 T145 T116 to damages,lung
R305 T145 T117 to damages,heart
R306 T145 T120 to damages,kidney
R307 T145 T146 to damages,testicle
R308 T15 T315 is_a COVID-19,these
R309 T30 T29 has_a persons,infected
R31 T92 T39 is_a over-reactivity,RAS
R310 T30 T41 of_a persons,RAS
R311 T148 T147 cause_of over-reaction,diffuse
R312 T95 T149 is_a hypovitaminosis D,imbalance
R313 T112 T218 on expressed,monocytes
R314 T112 T127 on expressed,macrophages
R315 T112 T219 on expressed,T-cells
R316 T328 T233 is_a Angiotensin A,cleavage
R317 T329 T233 is_a ARVYIHPF,cleavage
R318 T169 T197 is_a DRVYIHPFH,targets
R319 T222 T229 is_a Alamandine,bind
R320 T195 T221 is_a DRVYIHP,targeting
R321 T153 T196 is_a Angiotensin II,targets
R322 T167 T196 is_a DRVYIHPF,targets
R323 T33 T20 has_a patients,COVID-19
R324 T80 T27 has_a humans,infected
R325 T80 T22 has_a humans,COVID-19
R326 T289 T182 is_a proposed molecules,ACE inhibitors
R327 T289 T283 is_a proposed molecules,blockers
R328 T289 T284 is_a proposed molecules,antagonists
R329 T283 T201 for blockers,AT1R
R330 T284 T201 for antagonists,AT1R
R331 T289 T286 is_a proposed molecules,Losartan
R332 T289 T285 is_a proposed molecules,Losartan
R333 T293 T79 is_a peptide drugs,'counter-regulatory'
R334 T293 T24 for peptide drugs,COVID-19
R335 T293 T194 coreference peptide drugs,Angiotensin 1-7
R336 T293 T249 coreference peptide drugs,Angiotensin 1-9
R337 T293 T250 coreference peptide drugs,Alamandine
R338 T293 T253 coreference peptide drugs,Angiotensin A
R339 T293 T165 coreference peptide drugs,Angiotensin IV
R4 T36 T35 abbreviation RAS,'Renin-Angiotensin' System
R41 T96 T97 has_status acute respiratory distress syndrome,lethal
R42 T94 T87 cause_of hypovitaminosis D,cytokine storm
R43 T94 T96 cause_of hypovitaminosis D,acute respiratory distress syndrome
R44 T39 T87 cause_of RAS,cytokine storm
R45 T39 T96 cause_of RAS,acute respiratory distress syndrome
R48 T101 T110 abbreviation ACE2,Angiotensin-Converting Enzyme 2
R49 T3 T13 cause_of SARS-CoV-2,COVID-19
R5 T37 T62 abbreviation RAS,'Renin-Angiotensin' system
R51 T100 T110 to interacting,Angiotensin-Converting Enzyme 2
R52 T98 T100 is_a spike (S) glycoprotein,interacting
R53 T100 T123 is_a interacting,interfere
R54 T123 T40 is_a interfere,RAS
R55 T128 T126 - immune,macrophages
R56 T114 T113 in blood vessels,epithelial cells
R57 T115 T113 in lung,epithelial cells
R58 T119 T113 in kidney,epithelial cells
R59 T69 T113 in renal tubules,epithelial cells
R6 T63 T25 is_a Counter-regulatory,'Renin-Angiotensin' System
R60 T124 T113 in intestine,epithelial cells
R61 T118 T113 in heart,epithelial cells
R66 T4 T14 cause_of SARS-CoV-2,COVID-19
R7 T65 T62 synonym 'Renin-Angiotensin-Aldosterone' system,'Renin-Angiotensin' system
R83 T148 T41 is_a over-reaction,RAS
R85 T15 T147 has_status COVID-19,diffuse
R87 T149 T42 is_a imbalance,RAS
R89 T149 T148 coreference imbalance,over-reaction
R90 T121 T150 in kidney,Renin
R91 T122 T151 in liver,Angiotensinogen
R92 T150 T170 using Renin,cleaves
R97 T174 T173 abbreviation ACE,Angiotensin-Converting Enzyme