| Id |
Subject |
Object |
Predicate |
Lexical cue |
tao:has_database_id |
| 2170 |
18-21 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2171 |
98-101 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2181 |
180-186 |
Disease |
denotes |
tumors |
MESH:D009369 |
| 2182 |
543-549 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2172 |
764-767 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2157 |
809-813 |
Gene |
denotes |
P-gp |
Gene:283871 |
| 2158 |
815-820 |
Gene |
denotes |
ABCB1 |
Gene:5243 |
| 2183 |
899-911 |
Disease |
denotes |
cytotoxicity |
MESH:D064420 |
| 2184 |
915-933 |
Disease |
denotes |
refractory cancers |
MESH:D009369 |
| 2185 |
1009-1015 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2186 |
1061-1066 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2173 |
1165-1168 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2187 |
1383-1388 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2167 |
1433-1439 |
Species |
denotes |
murine |
Tax:10090 |
| 2188 |
1450-1482 |
Disease |
denotes |
pancreatic ductal adenocarcinoma |
MESH:D021441 |
| 2189 |
1494-1500 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2190 |
1513-1522 |
Disease |
denotes |
mortality |
MESH:D003643 |
| 2168 |
1569-1573 |
Species |
denotes |
Mice |
Tax:10090 |
| 2159 |
1605-1609 |
Gene |
denotes |
KRAS |
Gene:16653 |
| 2160 |
1635-1638 |
Gene |
denotes |
p53 |
Gene:22060 |
| 2191 |
1691-1696 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2174 |
1714-1717 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2161 |
1782-1785 |
Gene |
denotes |
p53 |
Gene:22060 |
| 2175 |
1818-1821 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2192 |
1836-1841 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2162 |
1949-1952 |
Gene |
denotes |
p53 |
Gene:22060 |
| 2163 |
1978-1981 |
Gene |
denotes |
p53 |
Gene:22060 |
| 2193 |
2002-2008 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2194 |
2060-2093 |
Disease |
denotes |
pancreatic ductal adenocarcinomas |
MESH:D021441 |
| 2176 |
2170-2173 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2195 |
2185-2190 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2177 |
2299-2302 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2196 |
2341-2373 |
Disease |
denotes |
pancreatic ductal adenocarcinoma |
MESH:D021441 |
| 2164 |
2402-2405 |
Gene |
denotes |
p53 |
Gene:22060 |
| 2165 |
2567-2570 |
Gene |
denotes |
p53 |
Gene:22060 |
| 2169 |
2609-2613 |
Species |
denotes |
mice |
Tax:10090 |
| 2166 |
2639-2643 |
Gene |
denotes |
KRAS |
Gene:16653 |
| 2197 |
2711-2736 |
Disease |
denotes |
pancreatic carcinogenesis |
MESH:D063646 |
| 2178 |
2800-2810 |
Chemical |
denotes |
trametinib |
MESH:C560077 |
| 2179 |
2971-2974 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2180 |
2998-3008 |
Chemical |
denotes |
trametinib |
MESH:C560077 |
| 2198 |
3054-3079 |
Disease |
denotes |
reduction of tumor lesion |
MESH:D051437 |
| 2199 |
3098-3103 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2200 |
3116-3122 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2201 |
3134-3138 |
Disease |
denotes |
pain |
MESH:D010146 |
| 2261 |
3149-3155 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2262 |
3171-3178 |
Disease |
denotes |
ovarian |
MESH:D010049 |
| 2243 |
3195-3200 |
Species |
denotes |
human |
Tax:9606 |
| 2263 |
3201-3214 |
Disease |
denotes |
breast cancer |
MESH:D001943 |
| 2246 |
3261-3264 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2264 |
3283-3288 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2265 |
3444-3450 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2247 |
3525-3528 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2266 |
3532-3538 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2248 |
3562-3572 |
Chemical |
denotes |
Epirubicin |
MESH:D015251 |
| 2267 |
3592-3605 |
Disease |
denotes |
breast cancer |
MESH:D001943 |
| 2268 |
3749-3755 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2249 |
3792-3795 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2269 |
3884-3889 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2242 |
3962-3979 |
Gene |
denotes |
estrogen receptor |
Gene:2099 |
| 2270 |
3989-4003 |
Disease |
denotes |
breast cancers |
MESH:D001943 |
| 2250 |
4043-4052 |
Chemical |
denotes |
tamoxifen |
MESH:D013629 |
| 2251 |
4115-4118 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2244 |
4131-4135 |
Species |
denotes |
mice |
Tax:10090 |
| 2252 |
4148-4153 |
Chemical |
denotes |
water |
MESH:D014867 |
| 2271 |
4186-4192 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2253 |
4202-4211 |
Chemical |
denotes |
tamoxifen |
MESH:D013629 |
| 2245 |
4222-4226 |
Species |
denotes |
mice |
Tax:10090 |
| 2272 |
4256-4265 |
Disease |
denotes |
carcinoma |
MESH:D009369 |
| 2254 |
4267-4270 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2273 |
4345-4350 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2255 |
4384-4387 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2256 |
4417-4428 |
Chemical |
denotes |
vemurafenib |
MESH:D000077484 |
| 2257 |
4533-4536 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2258 |
4552-4559 |
Chemical |
denotes |
CCI-779 |
MESH:C401859 |
| 2274 |
4643-4657 |
Disease |
denotes |
melanoma tumor |
MESH:D008545 |
| 2275 |
4678-4683 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2259 |
4736-4739 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2276 |
4779-4805 |
Disease |
denotes |
chemoresistant lung cancer |
MESH:D008175 |
| 2277 |
4823-4829 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2278 |
4835-4842 |
Disease |
denotes |
hypoxic |
MESH:D000860 |
| 2279 |
4886-4892 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2260 |
4979-4982 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2280 |
5045-5050 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2281 |
5140-5145 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2292 |
5334-5340 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2293 |
5420-5436 |
Disease |
denotes |
ascites hepatoma |
MESH:D001201 |
| 2289 |
5445-5449 |
Species |
denotes |
mice |
Tax:10090 |
| 2290 |
5488-5491 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2291 |
5541-5556 |
Chemical |
denotes |
3-bromopyruvate |
MESH:C017092 |
| 2294 |
5591-5596 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2295 |
5748-5754 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2434 |
5859-5874 |
Disease |
denotes |
β-Cell Lymphoma |
MESH:D016399 |
| 2380 |
5881-5886 |
Gene |
denotes |
Bcl-2 |
Gene:596 |
| 2381 |
5891-5897 |
Gene |
denotes |
Bcl-xL |
Gene:598 |
| 2403 |
6021-6024 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2404 |
6069-6076 |
Chemical |
denotes |
ABT-737 |
MESH:C501332 |
| 2435 |
6099-6115 |
Disease |
denotes |
prostatic cancer |
MESH:D011471 |
| 2391 |
6126-6130 |
Species |
denotes |
mice |
Tax:10090 |
| 2405 |
6229-6232 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2406 |
6236-6243 |
Chemical |
denotes |
ABT-737 |
MESH:C501332 |
| 2382 |
6343-6348 |
Gene |
denotes |
Bcl-2 |
Gene:12043 |
| 2407 |
6385-6388 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2436 |
6421-6434 |
Disease |
denotes |
neuroblastoma |
MESH:D009447 |
| 2392 |
6443-6447 |
Species |
denotes |
mice |
Tax:10090 |
| 2437 |
6494-6499 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2438 |
6533-6543 |
Disease |
denotes |
metastases |
MESH:D009362 |
| 2393 |
6557-6561 |
Species |
denotes |
mice |
Tax:10090 |
| 2383 |
6688-6704 |
Gene |
denotes |
interferon-alpha |
Gene:111654 |
| 2439 |
6714-6720 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2384 |
6896-6912 |
Gene |
denotes |
interferon-alpha |
Gene:111654 |
| 2394 |
7002-7006 |
Species |
denotes |
mice |
Tax:10090 |
| 2440 |
7021-7044 |
Disease |
denotes |
neck squamous carcinoma |
MESH:D000077195 |
| 2385 |
7065-7081 |
Gene |
denotes |
interferon-alpha |
Gene:111654 |
| 2408 |
7087-7090 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2409 |
7115-7125 |
Chemical |
denotes |
wortmannin |
MESH:D000077191 |
| 2441 |
7175-7180 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2410 |
7283-7286 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2411 |
7338-7347 |
Chemical |
denotes |
melatonin |
MESH:D008550 |
| 2442 |
7358-7381 |
Disease |
denotes |
squamous cell carcinoma |
MESH:D002294 |
| 2395 |
7382-7387 |
Species |
denotes |
mouse |
Tax:10090 |
| 2412 |
7423-7432 |
Chemical |
denotes |
melatonin |
MESH:D008550 |
| 2413 |
7620-7623 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2414 |
7642-7651 |
Chemical |
denotes |
melatonin |
MESH:D008550 |
| 2443 |
7696-7701 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2444 |
7760-7765 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2386 |
7982-7990 |
Gene |
denotes |
Beclin 1 |
Gene:56208 |
| 2415 |
8003-8006 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2396 |
8021-8027 |
Species |
denotes |
murine |
Tax:10090 |
| 2445 |
8038-8051 |
Disease |
denotes |
breast cancer |
MESH:D001943 |
| 2446 |
8306-8317 |
Disease |
denotes |
tumor death |
MESH:D003643 |
| 2416 |
8319-8322 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2417 |
8343-8346 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2418 |
8471-8474 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2397 |
8549-8555 |
Species |
denotes |
humans |
Tax:9606 |
| 2419 |
8582-8585 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2420 |
8649-8661 |
Chemical |
denotes |
chlorambucil |
MESH:D002699 |
| 2447 |
8716-8740 |
Disease |
denotes |
leukemia/lymphoma cancer |
MESH:D009369 |
| 2398 |
8752-8757 |
Species |
denotes |
human |
Tax:9606 |
| 2399 |
8758-8763 |
Species |
denotes |
mouse |
Tax:10090 |
| 2448 |
8773-8791 |
Disease |
denotes |
Burkitt’s lymphoma |
MESH:D002051 |
| 2421 |
8848-8851 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2422 |
8856-8868 |
Chemical |
denotes |
chlorambucil |
MESH:D002699 |
| 2400 |
8900-8904 |
Species |
denotes |
mice |
Tax:10090 |
| 2449 |
8977-8985 |
Disease |
denotes |
toxicity |
MESH:D064420 |
| 2423 |
9051-9054 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2424 |
9139-9142 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2450 |
9152-9157 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2425 |
9245-9256 |
Chemical |
denotes |
doxorubicin |
MESH:D004317 |
| 2451 |
9277-9285 |
Disease |
denotes |
melanoma |
MESH:D008545 |
| 2390 |
9341-9344 |
Gene |
denotes |
CA4 |
Gene:12351 |
| 2387 |
9391-9394 |
Gene |
denotes |
CA4 |
Gene:12351 |
| 2426 |
9421-9424 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2452 |
9439-9444 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2463 |
9485-9489 |
CellLine |
denotes |
A549 |
CVCL:0023 |
| 2453 |
9490-9501 |
Disease |
denotes |
lung cancer |
MESH:D008175 |
| 2401 |
9505-9509 |
Species |
denotes |
mice |
Tax:10090 |
| 2388 |
9535-9538 |
Gene |
denotes |
CA4 |
Gene:12351 |
| 2454 |
9661-9666 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2427 |
9674-9677 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2428 |
9702-9706 |
Chemical |
denotes |
iron |
MESH:D007501 |
| 2429 |
9717-9720 |
Chemical |
denotes |
ROS |
MESH:D017382 |
| 2455 |
9839-9856 |
Disease |
denotes |
pancreatic cancer |
MESH:D010190 |
| 2456 |
10070-10086 |
Disease |
denotes |
liver metastases |
MESH:D009362 |
| 2430 |
10137-10140 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2389 |
10209-10213 |
Gene |
denotes |
IL-6 |
Gene:3569 |
| 2457 |
10260-10266 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2458 |
10332-10347 |
Disease |
denotes |
stroma fibrosis |
MESH:D005355 |
| 2431 |
10358-10368 |
Chemical |
denotes |
paclitaxel |
MESH:D017239 |
| 2459 |
10389-10394 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2432 |
10447-10450 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2460 |
10463-10480 |
Disease |
denotes |
pancreatic cancer |
MESH:D010190 |
| 2433 |
10506-10509 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2402 |
10618-10626 |
Species |
denotes |
patients |
Tax:9606 |
| 2461 |
10659-10676 |
Disease |
denotes |
pancreatic cancer |
MESH:D010190 |
| 2462 |
10713-10732 |
Disease |
denotes |
progressive disease |
MESH:D018450 |
| 2480 |
10899-10904 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2475 |
10987-10990 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2481 |
11052-11064 |
Disease |
denotes |
brain tumors |
MESH:D001932 |
| 2476 |
11183-11186 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2477 |
11221-11227 |
Chemical |
denotes |
ZD6474 |
MESH:C452423 |
| 2482 |
11288-11294 |
Disease |
denotes |
glioma |
MESH:D005910 |
| 2474 |
11303-11307 |
Species |
denotes |
mice |
Tax:10090 |
| 2478 |
11342-11348 |
Chemical |
denotes |
ZD6474 |
MESH:C452423 |
| 2479 |
11443-11446 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2483 |
11496-11502 |
Disease |
denotes |
glioma |
MESH:D005910 |
| 2541 |
11550-11553 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2559 |
11630-11642 |
Disease |
denotes |
glioblastoma |
MESH:D005909 |
| 2531 |
11643-11651 |
Species |
denotes |
patients |
Tax:9606 |
| 2542 |
11667-11679 |
Chemical |
denotes |
temozolomide |
MESH:D000077204 |
| 2560 |
11799-11804 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2561 |
11869-11877 |
Disease |
denotes |
toxicity |
MESH:D064420 |
| 2543 |
11921-11924 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2532 |
11999-12006 |
Species |
denotes |
patient |
Tax:9606 |
| 2562 |
12042-12050 |
Disease |
denotes |
toxicity |
MESH:D064420 |
| 2563 |
12062-12078 |
Disease |
denotes |
myelosuppression |
MESH:D001855 |
| 2564 |
12080-12088 |
Disease |
denotes |
anorexia |
MESH:D000855 |
| 2565 |
12090-12097 |
Disease |
denotes |
fatigue |
MESH:D005221 |
| 2566 |
12102-12108 |
Disease |
denotes |
nausea |
MESH:D009325 |
| 2544 |
12144-12147 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2533 |
12252-12256 |
Species |
denotes |
mice |
Tax:10090 |
| 2545 |
12279-12282 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2546 |
12382-12385 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2534 |
12487-12495 |
Species |
denotes |
patients |
Tax:9606 |
| 2567 |
12507-12513 |
Disease |
denotes |
tumors |
MESH:D009369 |
| 2568 |
12528-12536 |
Disease |
denotes |
melanoma |
MESH:D008545 |
| 2547 |
12596-12608 |
Chemical |
denotes |
temsirolimus |
MESH:C401859 |
| 2548 |
12630-12633 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2569 |
12682-12687 |
Disease |
denotes |
tumor |
MESH:D009369 |
| 2549 |
12740-12743 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2570 |
12784-12792 |
Disease |
denotes |
toxicity |
MESH:D064420 |
| 2535 |
12799-12807 |
Species |
denotes |
patients |
Tax:9606 |
| 2571 |
12824-12832 |
Disease |
denotes |
melanoma |
MESH:D008545 |
| 2550 |
12877-12889 |
Chemical |
denotes |
temozolomide |
MESH:D000077204 |
| 2551 |
12914-12917 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2536 |
12942-12950 |
Species |
denotes |
Patients |
Tax:9606 |
| 2572 |
13153-13163 |
Disease |
denotes |
toxicities |
MESH:D064420 |
| 2537 |
13247-13255 |
Species |
denotes |
patients |
Tax:9606 |
| 2573 |
13261-13268 |
Disease |
denotes |
myeloma |
MESH:D009101 |
| 2552 |
13311-13314 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2538 |
13374-13382 |
Species |
denotes |
patients |
Tax:9606 |
| 2553 |
13512-13515 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2554 |
13520-13530 |
Chemical |
denotes |
bortezomib |
MESH:D000069286 |
| 2574 |
13569-13576 |
Disease |
denotes |
myeloma |
MESH:D009101 |
| 2555 |
13630-13633 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2556 |
13651-13661 |
Chemical |
denotes |
bortezomib |
MESH:D000069286 |
| 2575 |
13767-13773 |
Disease |
denotes |
cancer |
MESH:D009369 |
| 2557 |
13816-13819 |
Chemical |
denotes |
HCQ |
MESH:D006886 |
| 2576 |
13856-13864 |
Disease |
denotes |
toxicity |
MESH:D064420 |
| 2558 |
13904-13914 |
Chemical |
denotes |
everolimus |
MESH:D000068338 |
| 2577 |
13988-14019 |
Disease |
denotes |
clear-cell renal cell carcinoma |
MESH:C538614 |
| 2539 |
14020-14028 |
Species |
denotes |
patients |
Tax:9606 |
| 2540 |
14100-14108 |
Species |
denotes |
patients |
Tax:9606 |
