PMC:7335494 / 1760-101921 JSONTXT 13 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T27 107-113 GO:0016265 denotes deaths
T28 238-252 UBERON:0004535 denotes Cardiovascular
T29 363-368 UBERON:0002107 denotes liver
T30 914-918 UBERON:0000104 denotes life
T31 930-936 NCBITaxon:9606 denotes people
T32 1070-1074 UBERON:0000104 denotes life
T33 1125-1129 UBERON:0000104 denotes life
T34 1247-1255 CHEBI:60004;CHEBI:60004 denotes mixtures
T35 1382-1388 GO:0016265 denotes deaths
T36 1543-1549 GO:0016265 denotes deaths
T37 1676-1682 UBERON:0000479 denotes tissue
T38 1695-1712 GO:0051866 denotes cellular adaptive
T39 1741-1747 UBERON:0000479;GO:0001894 denotes tissue
T40 1748-1759 GO:0001894 denotes homeostasis
T41 1792-1801 GO:0002437 denotes responses
T42 1836-1847 GO:0000075 denotes checkpoints
T43 2076-2092 CHEBI:67079;CHEBI:67079 denotes pro-inflammatory
T44 2093-2102 CHEBI:36357;CHEBI:36357 denotes molecules
T45 2258-2265 GO:0006952 denotes defence
T46 2334-2342 CHEBI:75958;CHEBI:75958 denotes solution
T47 2412-2419 UBERON:0000479 denotes tissues
T48 2449-2462 GO:0065007 denotes dysregulation
T49 2502-2518 PR:000013428 denotes cyclooxygenase-2
T50 2520-2525 PR:000013428 denotes COX-2
T51 2528-2578 PR:000002089 denotes signal transducer and activator of transcription 3
T52 2580-2585 PR:000002089 denotes STAT3
T53 2588-2594 GO:0031012;PR:000010491 denotes matrix
T54 2595-2614 PR:000010491 denotes metalloproteinase-9
T55 2616-2621 PR:000010491 denotes MMP-9
T56 2648-2650 GO:0005883 denotes NF
T57 2713-2717 PR:000001393 denotes IL-6
T58 2719-2723 PR:000001395 denotes IL-8
T59 2756-2761 PR:000000134 denotes TNF-α
T60 2778-2787 CHEBI:36357;CHEBI:36357 denotes molecules
T61 2930-2943 CHEBI:67079;CHEBI:67079 denotes -inflammatory
T62 2944-2953 CHEBI:36357;CHEBI:36357 denotes molecules
T63 3000-3012 CHEBI:67079;CHEBI:67079 denotes inflammatory
T64 3031-3040 CHEBI:36357;CHEBI:36357 denotes molecules
T65 3206-3228 CHEBI:52217;CHEBI:52217 denotes pharmacological agents
T66 3367-3373 GO:0016265 denotes deaths
T67 3442-3448 NCBITaxon:33208 denotes animal
T68 3460-3465 SP_6;NCBITaxon:9606 denotes human
T69 3739-3741 GO:0005883 denotes NF
T70 3766-3769 PR:Q9FJR1 denotes p65
T71 3774-3777 PR:Q43731 denotes p50
T72 3807-3811 PR:000003293 denotes IκBα
T73 3852-3861 GO:0005737 denotes cytoplasm
T74 3930-3934 PR:000001395 denotes IL-8
T75 3936-3941 PR:000001136 denotes IL-1β
T76 3943-3947 PR:000001393 denotes IL-6
T77 3952-3957 PR:000000134 denotes TNF-α
T78 4007-4011 PR:000003293 denotes IκBα
T79 4049-4052 PR:Q43731 denotes p50
T80 4057-4060 PR:Q9FJR1 denotes p65
T81 4083-4090 GO:0005634 denotes nucleus
T82 4103-4111 SO:0000167 denotes promoter
T83 4135-4140 SO:0000704 denotes genes
T84 4242-4254 GO:0001525 denotes angiogenesis
T85 4281-4286 SO:0000704 denotes genes
T86 4287-4296 GO:0065007 denotes regulated
T87 4300-4302 GO:0005883 denotes NF
T88 4327-4337 GO:0010467 denotes expression
T89 4341-4346 PR:000000134 denotes TNF-α
T90 4348-4353 PR:000013428 denotes COX-2
T91 4355-4360 PR:000010491 denotes MMP-9
T92 4362-4374 CHEBI:16480;CHEBI:16480 denotes nitric oxide
T93 4430-4434 PR:000001393 denotes IL-6
T94 4439-4443 PR:000001395 denotes IL-8
T95 4480-4491 UBERON:0001986 denotes endothelial
T96 4507-4511 PR:000017284 denotes VEGF
T97 4527-4532 SO:0000704 denotes genes
T98 4596-4605 MOP:0000568 denotes oxidative
T99 4794-4796 GO:0005883 denotes NF
T100 4858-4874 GO:0007623 denotes circadian rhythm
T101 4884-4889 GO:0007568 denotes aging
T102 4915-4921 NCBITaxon:33208 denotes animal
T103 5083-5087 SO:0000704;GO:0010467 denotes gene
T104 5088-5098 GO:0010467 denotes expression
T105 5193-5208 GO:0007623 denotes circadian clock
T106 5323-5328 PR:000002089 denotes STAT3
T107 5332-5341 GO:0005737 denotes cytoplasm
T108 5376-5381 PR:000009196 denotes JAK 1
T109 5464-5469 PR:000002089 denotes STAT3
T110 5482-5489 GO:0005634 denotes nucleus
T111 5562-5584 CHEBI:67079;CHEBI:67079 denotes inflammatory mediators
T112 5646-5653 CHEBI:52290;CHEBI:52290 denotes mitogen
T113 5731-5734 PR:000008220 denotes p38
T114 5743-5746 PR:000009232 denotes Jun
T115 5776-5789 GO:0005576 denotes extracellular
T116 5985-5992 GO:0005634;PR:000011170 denotes nuclear
T117 5993-5999 PR:000011170 denotes factor
T118 6000-6009 PR:000011170;CL:0000764 denotes erythroid
T119 6010-6028 PR:000011170 denotes 2-related factor 2
T120 6030-6034 PR:000011170 denotes Nrf2
T121 6037-6056 PR:000009232 denotes activator protein-1
T122 6065-6072 GO:0005634 denotes nuclear
T123 6083-6092 CL:0002627 denotes activated
T124 6093-6100 CL:0000084 denotes T cells
T125 6111-6138 PR:000008555 denotes hypoxia-inducible factor-1α
T126 6140-6146 PR:000008555 denotes HIF-1α
T127 6384-6389 PR:000009277 denotes Keap1
T128 6392-6427 PR:000009277 denotes Kelch-like ECH-associated protein 1
T129 6429-6433 PR:000006048 denotes Cul3
T130 6436-6444 PR:000006048 denotes Cullin 3
T131 6446-6450 PR:000011170 denotes Nrf2
T132 6453-6460 GO:0005634;PR:000011170 denotes Nuclear
T133 6461-6467 PR:000011170 denotes factor
T134 6468-6477 PR:000011170;CL:0000764 denotes erythroid
T135 6478-6496 PR:000011170 denotes 2-related factor 2
T136 6504-6514 PR:000001775 denotes IκB kinase
T137 6516-6518 GO:0005883 denotes NF
T138 6557-6565 SO:0000165 denotes enhancer
T139 6569-6578 CL:0002627 denotes activated
T140 6579-6586 CL:0000236 denotes B cells
T141 6614-6617 PR:Q43731 denotes p50
T142 6619-6622 PR:Q9FJR1 denotes p65
T143 6627-6631 PR:000003293 denotes IkBα
T144 6642-6647 PR:000002089 denotes STAT3
T145 6650-6700 PR:000002089 denotes Signal transducer and activator of transcription 3
T146 6713-6720 CHEBI:52290;CHEBI:52290 denotes mitogen
T147 6898-6901 PR:000009232 denotes AP1
T148 6904-6923 PR:000009232 denotes Activator protein 1
T149 6998-7001 PR:000010045 denotes Maf
T174 7082-7092 GO:0065007;CL:0000815 denotes regulatory
T175 7093-7097 CL:0000815 denotes cell
T176 7132-7142 PR:000001775 denotes IκB kinase
T177 7155-7163 MOP:0000780 denotes cleavage
T178 7167-7169 GO:0005883 denotes NF
T179 7190-7197 GO:0005634;GO:0051169 denotes nuclear
T180 7198-7211 GO:0051169 denotes translocation
T181 7216-7219 PR:Q43731 denotes p50
T182 7224-7227 PR:Q9FJR1 denotes p65
T183 7279-7282 PR:000008220 denotes p38
T184 7318-7330 GO:0046983 denotes dimerization
T185 7334-7339 PR:000002089 denotes STAT3
T186 7469-7473 SO:0000704;GO:0010467 denotes gene
T187 7474-7484 GO:0010467 denotes expression
T188 7500-7512 CHEBI:67079;CHEBI:67079 denotes inflammatory
T189 7513-7522 CHEBI:36357;CHEBI:36357 denotes molecules
T190 7546-7556 GO:0010467 denotes expression
T191 7631-7635 PR:000011170 denotes Nrf2
T192 7668-7675 GO:0005634 denotes nuclear
T193 7783-7791 GO:0044237 denotes cellular
T194 7796-7805 GO:0008152 denotes metabolic
T195 7923-7932 GO:0008152 denotes metabolic
T196 8016-8020 UBERON:0000104 denotes life
T197 8440-8447 PR:000009054 denotes insulin
T198 8460-8474 UBERON:0001013 denotes Adipose tissue
T199 8562-8571 CL:0000136 denotes adipocyte
T200 8630-8644 UBERON:0001013 denotes adipose tissue
T201 8654-8665 CL:0000864 denotes macrophages
T202 8802-8815 CL:0002334 denotes preadipocytes
T203 8845-8860 CL:0000445 denotes apoptotic cells
T204 8862-8874 GO:0001525 denotes angiogenesis
T205 8910-8924 UBERON:0001013 denotes adipose tissue
T206 9006-9012 PR:000008555 denotes HIF-1α
T207 9046-9055 CL:0000576 denotes monocytes
T208 9117-9128 CL:0000863 denotes macrophages
T209 9151-9156 PR:000000134 denotes TNF-α
T210 9158-9166 CL:0000576 denotes monocyte
T211 9188-9193 PR:000002122 denotes MCP-1
T212 9208-9212 PR:000001395 denotes IL-8
T213 9294-9304 CL:0000136 denotes adipocytes
T214 9315-9324 CL:0000136 denotes adipocyte
T215 9349-9360 CHEBI:35366;CHEBI:35366 denotes fatty acids
T216 9400-9416 CHEBI:26523;CHEBI:26523 denotes reactive species
T217 9626-9635 GO:0008152 denotes Metabolic
T218 9705-9727 CHEBI:67079;CHEBI:67079 denotes inflammatory mediators
T219 9729-9734 PR:000001376 denotes IL-18
T220 9736-9741 PR:000001136 denotes IL-1β
T221 9797-9812 GO:0051260 denotes oligomerization
T222 9813-9819 SO:0000417 denotes domain
T223 9849-9854 PR:000010313 denotes pyrin
T224 9855-9861 SO:0000417 denotes domain
T225 9876-9881 PR:000011271 denotes NLRP3
T226 9897-9908 GO:0005737 denotes cytoplasmic
T227 9909-9916 GO:0032991 denotes complex
T228 9930-9935 PR:000011271 denotes NLRP3
T229 9962-9972 GO:0065007 denotes modulating
T230 9992-10005 UBERON:0002405 denotes immune system
T231 10145-10152 CHEBI:17234;CHEBI:17234 denotes glucose
T232 10196-10201 PR:000001376 denotes IL-18
T233 10213-10218 PR:000001136 denotes IL-1β
T234 10283-10285 GO:0005883;GO:0051092 denotes NF
T235 10285-10299 GO:0051092 denotes -κB activation
T236 10605-10615 GO:0010467 denotes expression
T237 10619-10631 CHEBI:35472;CHEBI:35472 denotes inflammatory
T238 10632-10641 CHEBI:36357;CHEBI:36357 denotes molecules
T239 10764-10773 GO:0008152 denotes metabolic
T240 10842-10855 GO:0005576 denotes extracellular
T241 10856-10864 GO:0031012 denotes matrices
T242 10866-10870 GO:0031012 denotes ECMs
T243 10929-10942 CL:0000630 denotes support cells
T244 10946-10953 UBERON:0000479 denotes tissues
T245 10962-10972 GO:0065007 denotes regulatory
T246 10985-11005 GO:0008150 denotes biological processes
T247 11021-11027 UBERON:0000479 denotes tissue
T248 11060-11064 GO:0044420 denotes ECMs
T249 11104-11117 CHEBI:37396;CHEBI:37396 denotes proteoglycans
T250 11130-11148 CHEBI:18085;CHEBI:18085 denotes glycosaminoglycans
T251 11175-11182 SO:0000417 denotes modules
T252 11199-11202 GO:0044420 denotes ECM
T253 11342-11353 GO:0042592 denotes homeostasis
T254 11531-11534 GO:0044420 denotes ECM
T255 11563-11572 CHEBI:67079;CHEBI:67079 denotes mediators
T256 11717-11720 GO:0044420 denotes ECM
T257 11734-11740 UBERON:0000479 denotes tissue
T258 11802-11808 UBERON:0000479 denotes tissue
T259 11899-11902 GO:0044420 denotes ECM
T260 11918-11927 GO:0008152 denotes metabolic
T261 12077-12091 UBERON:0001013 denotes adipose tissue
T262 12092-12095 GO:0044420 denotes ECM
T263 12113-12125 GO:0065007 denotes dysregulated
T264 12126-12139 GO:0005622;GO:0035556 denotes intracellular
T265 12140-12150 GO:0035556 denotes signalling
T266 12203-12210 PR:000009054 denotes insulin
T267 12273-12287 UBERON:0001013 denotes adipose tissue
T268 12288-12291 GO:0044420 denotes ECM
T269 12307-12318 PR:000007581 denotes fibronectin
T270 12379-12390 PR:000015561 denotes osteopontin
T271 12479-12485 SO:0000417 denotes domain
T272 12546-12549 GO:0044420 denotes ECM
T273 12570-12580 GO:0065007 denotes regulation
T274 12584-12598 UBERON:0001013 denotes adipose tissue
T275 12682-12687 CHEBI:18059;CHEBI:18059 denotes lipid
T276 12688-12694 UBERON:0000479 denotes tissue
T277 12743-12753 CL:0000136 denotes adipocytes
T278 12792-12802 CL:0000136 denotes adipocytes
T279 12826-12838 GO:0060612 denotes adipogenesis
T280 12854-12864 CL:0000034 denotes stem cells
T281 12925-12928 GO:0044420 denotes ECM
T282 12971-12980 GO:0065007 denotes regulates
T283 12981-12993 GO:0060612 denotes adipogenesis
T284 13032-13041 CL:0000136 denotes adipocyte
T285 13064-13076 GO:0042116 denotes migration of
T286 13077-13088 CL:0000235 denotes macrophages
T287 13093-13107 CL:0000071 denotes vascular cells
T288 13141-13144 GO:0044420 denotes ECM
T289 13204-13213 CHEBI:67079;CHEBI:67079 denotes mediators
T290 13230-13236 UBERON:0002405;CL:0000738 denotes immune
T291 13237-13242 CL:0000738 denotes cells
T292 13311-13316 CHEBI:18059;CHEBI:18059 denotes lipid
T293 13317-13323 UBERON:0000479 denotes tissue
T294 13371-13385 UBERON:0001013 denotes adipose tissue
T295 13386-13400 GO:0044420 denotes ECM components
T296 13426-13437 PR:000015561 denotes osteopontin
T297 13481-13491 CL:0000136 denotes adipocytes
T298 13521-13527 UBERON:0002405;CL:0000738 denotes immune
T299 13528-13533 CL:0000738 denotes cells
T300 13546-13552 UBERON:0000479 denotes tissue
T301 13570-13579 GO:0008152 denotes metabolic
T302 13651-13665 GO:0010467 denotes overexpression
T303 13700-13708 MOP:0000780 denotes cleavage
T304 13742-13748 PR:000003341 denotes Col6a3
T305 13813-13827 UBERON:0001013 denotes adipose tissue
T306 13845-13852 PR:000009054 denotes insulin
T307 13921-13931 GO:0010467 denotes expression
T308 13935-13940 PR:000010474 denotes MMP14
T309 13972-13986 UBERON:0001013 denotes adipose tissue
T310 14007-14011 NCBITaxon:10088 denotes mice
T311 14028-14033 PR:000010474 denotes MMP14
T312 14034-14045 GO:0006508 denotes proteolytic
T313 14131-14141 CL:0000136 denotes adipocytes
T314 14179-14184 CHEBI:18059;CHEBI:18059;GO:0006629 denotes lipid
T315 14185-14195 GO:0006629 denotes metabolism
T316 14200-14207 PR:000009054 denotes insulin
T317 14323-14326 GO:0044420 denotes ECM
T318 14346-14352 UBERON:0000310 denotes breast
T319 14376-14390 UBERON:0001013 denotes adipose tissue
T320 14391-14403 UBERON:0005169 denotes interstitial
T321 14454-14465 CL:0000235 denotes macrophages
T322 14511-14522 CL:0000235 denotes macrophages
T323 14632-14641 GO:0038001 denotes paracrine
T324 14666-14677 CHEBI:35366;CHEBI:35366 denotes fatty acids
T325 14682-14687 PR:000000134 denotes TNF-α
T326 14709-14719 CL:0000136 denotes adipocytes
T327 14737-14748 CL:0000235 denotes macrophages
T328 14804-14818 UBERON:0001013 denotes adipose tissue
T329 14874-14886 CHEBI:37396;CHEBI:37396 denotes proteoglycan
T330 14930-14943 GO:0010467 denotes overexpressed
T331 14947-14950 GO:0044420 denotes ECM
T332 14954-14966 UBERON:0002190 denotes subcutaneous
T333 14967-14970 UBERON:0001013 denotes fat
T334 14974-14981 PR:000009054 denotes insulin
T335 14998-15009 NCBITaxon:1 denotes individuals
T336 15077-15088 GO:0065007 denotes dysregulate
T337 15089-15101 GO:0060612 denotes adipogenesis
T338 15114-15123 MOP:0000568 denotes oxidative
T339 15181-15188 PR:000009054 denotes insulin
T340 15316-15330 UBERON:0001013 denotes adipose tissue
T341 15387-15390 GO:0044420 denotes ECM
T342 15447-15450 GO:0044420 denotes ECM
T343 15456-15463 CHEBI:17234;CHEBI:17234;GO:0042593 denotes glucose
T344 15464-15475 GO:0042593 denotes homeostasis
T345 15484-15493 GO:0008152 denotes metabolic
T346 15525-15536 PR:000015561 denotes Osteopontin
T347 15541-15544 GO:0044420 denotes ECM
T348 15545-15557 CHEBI:17089;BV_11;CHEBI:17089 denotes glycoprotein
T349 15571-15579 GO:0046903 denotes secreted
T350 15583-15597 UBERON:0001013 denotes adipose tissue
T351 15598-15609 CL:0000235 denotes macrophages
T352 15643-15657 UBERON:0001013 denotes adipose tissue
T353 15700-15707 PR:000009054 denotes insulin
T354 15760-15773 GO:0044420 denotes ECM component
T355 15779-15796 CHEBI:18085;CHEBI:18085 denotes glycosaminoglycan
T356 16102-16110 GO:0032940 denotes secreted
T357 16139-16145 UBERON:0000479 denotes tissue
T358 16492-16512 PR:000001155 denotes Toll-like receptor 4
T359 16514-16518 PR:000001155 denotes TLR4
T360 16520-16522 GO:0005883 denotes NF
T361 16548-16556 GO:0065007 denotes regulate
T362 16570-16575 SO:0000704 denotes genes
T363 16593-16599 UBERON:0002405;CL:0000738 denotes immune
T364 16600-16605 CL:0000738 denotes cells
T365 16702-16709 UBERON:0000479 denotes tissues
T366 16799-16816 GO:0042593 denotes glycaemic control
T367 17058-17068 GO:0010467 denotes expression
T368 17072-17077 SO:0000704 denotes genes
T369 17094-17104 GO:0008152 denotes metabolism
T370 17105-17110 GO:0009081 denotes of HA
T371 17155-17164 CL:0000136 denotes adipocyte
T372 17283-17298 GO:0060612 denotes adipogenesis of
T373 17349-17356 PR:000009054 denotes insulin
T374 17413-17422 UBERON:0007808 denotes abdominal
T375 17423-17426 UBERON:0001013 denotes fat
T376 17434-17441 GO:0007631 denotes feeding
T377 17451-17456 NCBITaxon:10088 denotes mouse
T378 17509-17512 GO:0007631 denotes fed
T379 17519-17523 NCBITaxon:10088 denotes mice
T380 17552-17559 GO:0032991 denotes complex
T381 17567-17572 SP_6;NCBITaxon:9606 denotes human
T382 17648-17662 UBERON:0001013 denotes adipose tissue
T383 17680-17687 PR:000009054 denotes insulin
T384 17734-17743 GO:0008152 denotes metabolic
T385 17768-17771 CHEBI:13389;CHEBI:13389 denotes NAD
T386 17771-17772 CHEBI:15846;CHEBI:15846 denotes +
T387 17807-17815 CHEBI:10545;CHEBI:10545;MOP:0000615 denotes electron
T388 17816-17822 MOP:0000615 denotes supply
T389 17829-17842 GO:0065007 denotes dysregulation
T390 17865-17878 GO:0005739 denotes mitochondrial
T391 17903-17909 PR:000029756 denotes SIRT-3
T392 17937-17946 MOP:0000568 denotes oxidative
T393 17968-17978 CHEBI:35366;CHEBI:35366 denotes fatty acid
T394 17981-17990 MOP:0000568 denotes oxidation
T395 18029-18043 GO:1903409 denotes ROS production
T396 18093-18096 GO:0044420 denotes ECM
T397 18154-18163 MOP:0000568 denotes oxidative
T398 18187-18194 CHEBI:17234;CHEBI:17234 denotes glucose
T399 18206-18209 NCBITaxon:10114 denotes rat
T400 18210-18220 CL:1000742 denotes glomerular
T401 18221-18230 CL:1000742;UBERON:0003104 denotes mesangial
T402 18231-18236 CL:1000742 denotes cells
T403 18293-18304 PR:000007581 denotes fibronectin
T404 18337-18342 PR:000016867 denotes TXNIP
T405 18343-18348 PR:000011271 denotes NLRP3
T406 18349-18372 GO:0035556 denotes inflammasome signalling
T407 18426-18431 UBERON:0002113 denotes renal
T408 18432-18435 GO:0044420 denotes ECM
T409 18629-18645 CHEBI:50488;CHEBI:50488 denotes dihydroquercetin
T410 18719-18724 PR:000011271 denotes NLRP3
T411 18784-18787 GO:0044420 denotes ECM
T412 18791-18796 UBERON:0002113 denotes renal
T413 18843-18848 UBERON:0002113;CL:1000497 denotes renal
T414 18849-18854 CL:1000497 denotes cells
T415 18863-18870 CHEBI:17234;CHEBI:17234 denotes glucose
T416 18957-18960 GO:0044420 denotes ECM
T417 18980-18989 GO:0008152 denotes metabolic
T418 19026-19029 GO:0044420 denotes ECM
T419 19041-19044 GO:0044420 denotes ECM
T420 19272-19284 CHEBI:16646;CHEBI:16646 denotes Carbohydrate
T421 19385-19388 CHEBI:26523;CHEBI:26523 denotes ROS
T422 19434-19436 GO:0005883 denotes NF
T423 19461-19471 GO:0010467 denotes expression
T424 19478-19491 CHEBI:67079;CHEBI:67079 denotes -inflammatory
T425 19492-19501 CHEBI:36357;CHEBI:36357 denotes molecules
T426 19510-19515 PR:000002122 denotes MCP-1
T427 19517-19522 PR:000000134 denotes TNF-α
T428 19524-19528 PR:000001393 denotes IL-6
T429 19530-19535 PR:000001136 denotes IL-1β
T430 19543-19547 PR:000009232 denotes AP-1
T431 19572-19581 CHEBI:36357;CHEBI:36357 denotes molecules
T432 19601-19608 PR:000009054 denotes insulin
T433 19640-19647 PR:000009054 denotes insulin
T434 19724-19729 UBERON:0000178 denotes blood
T435 19879-19888 GO:0006096 denotes glycaemic
T436 19895-19899 CHEBI:33290;CHEBI:33290 denotes food
T437 20016-20028 CHEBI:35472;CHEBI:35472 denotes inflammatory
T438 20029-20038 CHEBI:36357;CHEBI:36357 denotes molecules
T439 20136-20148 CHEBI:16646;CHEBI:16646 denotes carbohydrate
T440 20149-20155 GO:0007631 denotes intake
T441 20202-20210 UBERON:0000104 denotes lifespan
T442 20231-20235 NCBITaxon:10088 denotes mice
T443 20248-20252 PR:000001393 denotes IL-6
T444 20259-20262 PR:000001136 denotes -1β
T445 20336-20341 UBERON:0001977 denotes serum
T446 20342-20349 CHEBI:17234;CHEBI:17234 denotes glucose
T447 20353-20360 PR:000009054 denotes insulin
T448 20429-20441 CHEBI:16646;CHEBI:16646 denotes carbohydrate
T449 20531-20538 CHEBI:17234;CHEBI:17234;GO:0006006 denotes glucose
T450 20586-20591 CHEBI:18059;CHEBI:18059;GO:0006629 denotes lipid
T451 20592-20602 GO:0006629 denotes metabolism
T452 20636-20641 UBERON:0002107 denotes liver
T453 20668-20678 UBERON:0001264 denotes pancreatic
T454 20739-20745 GO:0007631 denotes intake
T455 20794-20807 CHEBI:35472;CHEBI:35472 denotes -inflammatory
T456 20808-20817 CHEBI:36357;CHEBI:36357 denotes molecules
T457 20827-20832 PR:000001136 denotes IL-1β
T458 20909-20915 CHEBI:17087;CHEBI:17087 denotes ketone
T459 20916-20924 CHEBI:51307;CHEBI:51307 denotes diesters
T460 20962-20967 PR:000011271 denotes NLRP3
T461 21025-21036 UBERON:0002240 denotes spinal cord
T462 21047-21056 CHEBI:25754;CHEBI:25754;GO:0031424 denotes ketogenic
T463 21070-21079 MOP:0000568 denotes oxidative
T464 21128-21130 GO:0005883 denotes NF
T465 21198-21202 PR:000011170 denotes Nrf2
T466 21226-21231 PR:000000134 denotes TNF-α
T467 21233-21238 PR:000001136 denotes IL-1β
T468 21240-21245 PR:000000017 denotes IFN-γ
T469 21246-21256 GO:0010467 denotes expression
T607 21404-21410 GO:0007631 denotes intake
T797 21475-21476 UBERON:0001913 denotes i
T807 21511-21512 GO:0008152 denotes O
T810 21522-21523 CHEBI:36357;CHEBI:36357 denotes e
T816 21545-21547 CHEBI:67079;CHEBI:67079 denotes -o
T818 21554-21555 GO:0007259 denotes a
T837 21557-21559 PR:Q43731 denotes 50
T840 21561-21562 PR:000002089 denotes a
T859 21569-21570 GO:0008152 denotes b
T874 21572-21573 PR:000013428 denotes c
T876 21573-21574 PR:000000134 denotes t
T889 21586-21589 UBERON:0004535 denotes ris
T890 21594-21595 UBERON:0001977 denotes m
T895 21609-21610 GO:0010467 denotes o
T902 21624-21626 GO:0010467 denotes pe
T907 21627-21628 PR:000001776 denotes i
T908 21633-21635 CHEBI:26607;CHEBI:26607 denotes f
T909 21637-21638 CHEBI:16646;CHEBI:16646 denotes o
T910 21639-21640 GO:0010467 denotes e
T911 21641-21642 SO:0000704 denotes g
T918 21655-21656 PR:000001136 denotes 1
T994 21686-21687 CHEBI:50488;CHEBI:50488 denotes m
T996 21687-21688 CHEBI:28661;CHEBI:28661 denotes a
T1199 21699-21701 PR:000001417 denotes 10
T1202 21702-21703 CL:0000235 denotes g
T1234 21709-21710 GO:0005883;GO:0051092 denotes f
T1235 21710-21711 GO:0051092 denotes
T1247 21736-21737 UBERON:0000010 denotes a
T1257 21740-21741 CHEBI:28757;CHEBI:28757 denotes s
T1264 21748-21749 UBERON:0002107 denotes r
T1267 21753-21754 GO:0065007 denotes o
T1342 21763-21764 GO:0010467 denotes s
T1348 21769-21770 NCBITaxon:10088 denotes o
T1355 21774-21775 NCBITaxon:10088 denotes e
T1356 21775-21776 PR:000001092 denotes i
T1372 21777-21778 SP_6;NCBITaxon:9606 denotes h
T1382 21782-21784 GO:0010467 denotes er
T1396 21801-21802 CHEBI:16856;CHEBI:16856 denotes a
T1405 21806-21807 GO:0005777 denotes s
T1461 21822-21823 CHEBI:30751;CHEBI:30751 denotes a
T2012 22095-22098 GO:0007631 denotes in,
T2013 22103-22113 CHEBI:5086;CHEBI:5086 denotes Vulevic et
T2014 22114-22117 CHEBI:35218;CHEBI:35218 denotes al.
T2015 22129-22134 CHEBI:24043;CHEBI:24043 denotes omize
T2016 22136-22140 GO:0007631 denotes cont
T2017 22181-22187 PR:000009054 denotes ic syn
T2018 22202-22212 CHEBI:35218;CHEBI:35218 denotes of rye and
T2019 22213-22218 GO:0007631 denotes whole
T2021 22290-22292 GO:0007631 denotes ne
T2023 22465-22474 GO:0008152 denotes metabolic
T2024 22588-22600 PR:000001393 denotes calprotectin
T2025 22670-22692 CHEBI:26195;CHEBI:26195 denotes hypercholesterolemic s
T2026 22858-22862 UBERON:0000178 denotes lled
T2027 22941-22953 PR:000009054 denotes (RS2) versus
T2028 22957-22967 PR:000009054 denotes isocaloric
T2029 23030-23031 UBERON:0001969 denotes s
T2031 23479-23481 CHEBI:36357;CHEBI:36357 denotes or
T2032 23508-23519 UBERON:0004535 denotes to American
T2033 23697-23699 UBERON:0007023 denotes at
T2034 23837-23842 CHEBI:16113;CHEBI:16113 denotes white
T2035 23843-23847 CHEBI:17855;CHEBI:17855 denotes rice
T2036 23851-23861 CHEBI:12071;CHEBI:12071 denotes = 14) diet
T2037 24032-24041 CHEBI:21241;CHEBI:21241 denotes Diet (n =
T2038 24049-24060 CHEBI:26195;CHEBI:26195 denotes whole-grain
T2039 24067-24069 CHEBI:33290;CHEBI:33290 denotes ed
T2040 24102-24124 GO:0008152 denotes 45) diet, Healthy Diet
T2041 24157-24172 CHEBI:39015;CHEBI:39015 denotes and whole grain
T2043 24187-24188 PR:000001415 denotes e
T2044 24253-24268 CHEBI:26195;CHEBI:26195 denotes double-blind, s
T2045 24352-24360 GO:0008152 denotes mentable
T2046 24694-24707 MOP:0000568 denotes d fatty acids
T2047 24747-24751 PR:000001393 denotes IL-6
T2048 25092-25097 PR:000004155 denotes patie
T2049 25119-25134 CHEBI:16243;CHEBI:16243 denotes either resistan
T2050 25217-25225 CHEBI:16243;CHEBI:16243 denotes (2018) R
T2051 25325-25326 UBERON:0000178 denotes o
T2052 25778-25784 UBERON:0000178 denotes bre or
T2053 25999-26006 CHEBI:16412;CHEBI:16412 denotes periods
T2054 26073-26075 PR:000001395 denotes IL
T2055 26075-26078 PR:000001395;GO:1990774 denotes -10
T2058 26360-26400 PR:000009054 denotes inical trial 60 females with T2DM Patien
T2059 26491-26544 GO:0008152 denotes on IL-6 or CRP Gargari et al. (2015) Crossover clinic
T2060 26786-26835 SO:0000704 denotes et al. (2018) Observational study 49 T2DM females
T2061 26870-26876 PR:000009054 denotes inulin
T2062 27124-27149 CHEBI:47916;CHEBI:47916 denotes for 8 weeks oligofructose
T2063 27541-27554 CHEBI:47916;CHEBI:47916 denotes flammation. D
T2064 27562-27573 GO:0007631 denotes ies Treatme
T2065 27830-27884 CHEBI:33290;CHEBI:33290 denotes fatty acids He et al. (2019) Scandinavian low-carbohyd
T2066 28050-28074 PR:000009054 denotes in glycemia, TG, insulin
T2067 28406-28492 CHEBI:35218;CHEBI:35218 denotes Control: standard chow ➢ Ketogenic diet group KD: ↑ triglycerides, cholesterol, leptin
T2068 28522-28543 CHEBI:24043;CHEBI:24043 denotes β-cell mass Ellenbroe
T2069 28545-28561 GO:0007631 denotes et al. (2014) Ke
T2070 28908-28943 PR:000009054 denotes intolerance, steatosis, cellular in
T2071 29455-29499 GO:0007631 denotes Control: normal chow with 4.5% fat ➢ Study g
T2072 29546-29560 CHEBI:35218;CHEBI:35218 denotes anediol ketone
T2074 29870-29876 CHEBI:16412;CHEBI:16412 denotes expres
T2075 30260-30295 CHEBI:26195;CHEBI:26195 denotes type of carbohydrates and fats cons
T2076 31483-31500 GO:0008152 denotes et al., 2013). In
T2077 31627-31654 CHEBI:26195;CHEBI:26195 denotes portantly, these beneficial
T2078 31957-31968 CHEBI:26195;CHEBI:26195 denotes adolescents
T2079 33196-33240 CHEBI:26195;CHEBI:26195 denotes (LFD), ➢ followed by 12 weeks of high intens
T2080 33494-33531 UBERON:0001969 denotes (2018) Low-carbohydrate versus low-fa
T2082 33642-33688 MOP:0000568 denotes ow-fat diet (LFD) LCD: ↓ sICAM, E-selectinLFD:
T2083 33780-33836 UBERON:0001088 denotes 51 T2DM patients 6-month diet intervention:➢ Low-carbohy
T2084 33842-33859 CHEBI:35515;CHEBI:35515 denotes diet (LCD) ➢ Low-
T2085 33864-33913 CHEBI:30362;CHEBI:30362 denotes iet (LFD) LCD: ↓ IL-1Ra, IL-6 Johansson-Persson e
T2086 34104-34206 CHEBI:26195;CHEBI:26195 denotes diet – LFD, n = 73 (<30% kcal/day from total fat, <7% saturated fat) LCD: ↑ adiponectin ↓ICAM Hu et al
T2087 34438-34467 CHEBI:26195;CHEBI:26195 denotes proved glycaemic profile vers
T2088 34692-34723 CHEBI:16113;CHEBI:16113 denotes calorie (LC) diet, ➢ Group 2: L
T2089 35844-35932 CHEBI:26195;CHEBI:26195 denotes diet (LFHC) group HFLC: ↓ CRP,TG ↑ adiponectin, HDL Ruth et al. (2013) Nutritional ketos
T2090 36000-36034 GO:0008152 denotes intervention:➢ Nutritional ketosis
T2091 36035-36039 GO:0009081 denotes (NK,
T2092 36040-36041 CHEBI:29021;CHEBI:29021 denotes n
T2093 36105-36133 UBERON:0000178 denotes al. (2018) Moderate-carbohyd
T2094 36778-36782 CHEBI:51231;CHEBI:51231 denotes from
T2095 36839-36953 CHEBI:35218;CHEBI:35218 denotes aemic-index diet (LGI) (60% from carbohydrate, 25% from fat, and 15% from protein) ➢ LGI, rich in functional foods
T2096 37071-37097 CHEBI:15956;CHEBI:15956 denotes LGI: ↑ adiponectin Izadi e
T2097 37146-37156 CHEBI:33290;CHEBI:33290 denotes controlled
T2098 37232-37239 UBERON:0001977 denotes Healthy
T2099 37242-37270 CHEBI:17855;CHEBI:17855 denotes tritional recommendation die
T2100 38222-38248 CHEBI:26267;CHEBI:26267 denotes parative study 28 patients
T2101 38364-38368 GO:0007631 denotes ICAM
T2102 38379-38438 CHEBI:26195;CHEBI:26195 denotes of insulin and sICAM persistent, while CRP did not when res
T2103 38701-38749 CHEBI:26195;CHEBI:26195 denotes effects on inflammatory profile of T2DM and obes
T2104 39243-39285 GO:0008152 denotes med in moderate amounts, as is wine (espec
T2105 39367-39383 SP_7 denotes al., 2014; Tosti
T2106 39384-39403 GO:0008152 denotes et al., 2018). This
T2107 39582-39590 SP_7 denotes combined
T2108 39625-39659 UBERON:0001004 denotes reducing the systemic inflammatory
T2109 39848-39928 SP_7 denotes sses equilibrium (Martucci et al., 2017). Epigenetic regulation was also hypothe
T2110 39935-39952 SP_7;UBERON:0001004 denotes especially due to
T2111 39962-40058 SP_7 denotes s found in nuts and extra virgin olive oil, which were reported to alter the methylation of some
T2112 40063-40075 SP_7 denotes s related to
T2113 40955-40982 UBERON:0005169 denotes interleukins production via
T2114 41397-41417 UBERON:0000062 denotes or kappa-light-chain
T2116 42579-42584 SP_7 denotes ratio
T2117 43529-43552 SP_7 denotes coenzyme Q10 (MD-Q10) ➢
T2118 43587-43590 NCBITaxon:1 denotes ids
T2119 43937-43939 UBERON:0002405;GO:0006955 denotes in
T2120 43972-43979 GO:0006955 denotes ression
T2121 43983-43984 NCBITaxon:10239 denotes i
T2122 44178-44203 GO:0008152 denotes periods of 4 weeks in a c
T2123 44402-44439 SP_7 denotes (KMD-O3) KMD: ↓ TNF-αKMD-O3: ↓ IL-1β,
T2124 44628-44654 GO:0065007;CL:0000815 denotes RP (versus baseline) Tripp
T2125 44656-44677 CL:0000815 denotes t al. (2019) Clinical
T2128 45252-45303 NCBITaxon:1 denotes il Low fat diet (LFD) MD: ↓ IL-6, ICAM-1, ↑ GLP-1 s
T2129 45450-45452 UBERON:0002405;CL:0000738 denotes ie
T2130 45454-45459 CL:0000738 denotes (LFD)
T2131 45622-45661 CHEBI:67079;CHEBI:67079 denotes diet (LFD) ↓ dietary inflammatory index
T2132 45673-45678 PR:000001393 denotes IL-1b
T2133 45699-45704 PR:000000134 denotes TNF-α
T2134 45735-45750 CL:0000235;PR:000002123 denotes mized Controlle
T2135 45754-45829 PR:000002123 denotes ial 164 subjects with high cardiovascular risk 12-month diet intervention:➢
T2136 46067-46087 CHEBI:67079;CHEBI:67079 denotes of a diet similar to
T2137 46175-46185 UBERON:0001004;GO:0045333 denotes especially
T2138 46187-46215 UBERON:0000483 denotes erries, and vegetables, fish
T2139 46460-46513 SP_7 denotes reports are reviewed elsewhere (Lankinen et al., 2019
T2140 46855-46864 GO:0008152 denotes metabolic
T25 53923-53934 CHEBI:26195;CHEBI:26195 denotes Polyphenols
T2141 97741-97749 SP_7 denotes COVID-19
T2142 98007-98020 UBERON:0002405 denotes immune system
T62234 98007-98020 UBERON:0002405 denotes immune system
T2143 98109-98120 CHEBI:26195;CHEBI:26195 denotes polyphenols
T86339 98109-98120 CHEBI:26195;CHEBI:26195 denotes polyphenols
T2144 98267-98272 NCBITaxon:10239 denotes virus
T53424 98267-98272 NCBITaxon:10239 denotes virus
T2145 98377-98387 GO:0065007 denotes regulating
T82471 98377-98387 GO:0065007 denotes regulating
T2146 98479-98487 GO:0007631 denotes ingested
T24720 98479-98487 GO:0007631 denotes ingested
T2147 98681-98685 UBERON:0000104 denotes life
T90996 98681-98685 UBERON:0000104 denotes life
T33658 98681-98685 UBERON:0000104 denotes life
T2148 98796-98801 UBERON:0004905 denotes joint
T64396 98796-98801 UBERON:0004905 denotes joint
T2149 98822-98831 CHEBI:36357;CHEBI:36357 denotes molecules
T19892 98822-98831 CHEBI:36357;CHEBI:36357 denotes molecules
T2150 98878-98892 CHEBI:50733;CHEBI:50733 denotes nutraceuticals
T15009 98878-98892 CHEBI:50733;CHEBI:50733 denotes nutraceuticals
T2151 98905-98911 GO:0007631 denotes intake
T26033 98905-98911 GO:0007631 denotes intake
T2152 98991-98999 GO:0044237 denotes cellular
T58405 98991-98999 GO:0044237 denotes cellular
T2153 99004-99013 GO:0008152 denotes metabolic
T73290 99004-99013 GO:0008152 denotes metabolic
T2154 99033-99042 CHEBI:36357;CHEBI:36357 denotes compounds
T75044 99033-99042 CHEBI:36357;CHEBI:36357 denotes compounds
T2155 99181-99189 GO:0046959 denotes habitual
T61810 99181-99189 GO:0046959 denotes habitual
T2156 99190-99201 GO:0007631 denotes consumption
T78336 99190-99201 GO:0007631 denotes consumption
T2157 99216-99231 CHEBI:52217;CHEBI:52217 denotes pharmacological
T74982 99216-99231 CHEBI:52217;CHEBI:52217 denotes pharmacological
T2158 99559-99564 NCBITaxon:10239 denotes viral
T5787 99559-99564 NCBITaxon:10239 denotes viral
T2159 99659-99667 SP_7 denotes COVID-19
T48907 99659-99667 SP_7 denotes COVID-19
T2160 99668-99679 UBERON:0001004 denotes respiratory
T86218 99668-99679 UBERON:0001004 denotes respiratory
T2161 99895-99901 UBERON:0002405;GO:0006955 denotes immune
T22883 99895-99901 UBERON:0002405;GO:0006955 denotes immune
T2162 99902-99910 GO:0006955 denotes response
T47508 99902-99910 GO:0006955 denotes response