PMC:7335494 JSONTXT 20 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 53-64 CHEBI:26208;CHEBI:26208 denotes fatty acids
T24056 53-64 CHEBI:26208;CHEBI:26208 denotes fatty acids
T2 69-80 CHEBI:26195;CHEBI:26195 denotes polyphenols
T40789 69-80 CHEBI:26195;CHEBI:26195 denotes polyphenols
T3 210-224 UBERON:0004535 denotes cardiovascular
T3357 210-224 UBERON:0004535 denotes cardiovascular
T4 329-334 UBERON:0002107 denotes liver
T64893 329-334 UBERON:0002107 denotes liver
T5 396-404 SP_7 denotes COVID-19
T46621 396-404 SP_7 denotes COVID-19
T6 485-491 UBERON:0000062 denotes organs
T3876 485-491 UBERON:0000062 denotes organs
T7 583-596 GO:0065007 denotes dysregulation
T7132 583-596 GO:0065007 denotes dysregulation
T8 678-689 CHEBI:26195;CHEBI:26195 denotes polyphenols
T59007 678-689 CHEBI:26195;CHEBI:26195 denotes polyphenols
T9 708-719 CHEBI:27208;CHEBI:27208 denotes fatty acids
T14784 708-719 CHEBI:27208;CHEBI:27208 denotes fatty acids
T10 880-889 GO:0008152 denotes metabolic
T64763 880-889 GO:0008152 denotes metabolic
T11 890-901 GO:0042592 denotes homeostasis
T37528 890-901 GO:0042592 denotes homeostasis
T12 906-912 UBERON:0002405;CL:0000738 denotes immune
T92317 906-912 UBERON:0002405;CL:0000738 denotes immune
T13 913-918 CL:0000738 denotes cells
T16212 913-918 CL:0000738 denotes cells
T14 1090-1095 NCBITaxon:3193 denotes plant
T36854 1090-1095 NCBITaxon:3193 denotes plant
T15 1113-1125 CHEBI:26195;CHEBI:26195 denotes polyphenolic
T30287 1113-1125 CHEBI:26195;CHEBI:26195 denotes polyphenolic
T16 1126-1135 CHEBI:36357;CHEBI:36357 denotes compounds
T20129 1126-1135 CHEBI:36357;CHEBI:36357 denotes compounds
T17 1289-1302 UBERON:0002405;GO:0006955 denotes immune system
T64962 1289-1302 UBERON:0002405;GO:0006955 denotes immune system
T18 1410-1424 CHEBI:50733;CHEBI:50733 denotes Nutraceuticals
T67148 1410-1424 CHEBI:50733;CHEBI:50733 denotes Nutraceuticals
T19 1487-1492 PR:P03882 denotes Omega
T75861 1487-1492 PR:P03882 denotes Omega
T20 1511-1522 CHEBI:26208;CHEBI:26208 denotes fatty acids
T5936 1511-1522 CHEBI:26208;CHEBI:26208 denotes fatty acids
T21 1570-1581 CHEBI:26195;CHEBI:26195 denotes Polyphenols
T87684 1570-1581 CHEBI:26195;CHEBI:26195 denotes Polyphenols
T22 1647-1659 CHEBI:16646;CHEBI:16646 denotes Carbohydrate
T81380 1647-1659 CHEBI:16646;CHEBI:16646 denotes Carbohydrate
T27 1867-1873 GO:0016265 denotes deaths
T28 1998-2012 UBERON:0004535 denotes Cardiovascular
T29 2123-2128 UBERON:0002107 denotes liver
T30 2674-2678 UBERON:0000104 denotes life
T31 2690-2696 NCBITaxon:9606 denotes people
T32 2830-2834 UBERON:0000104 denotes life
T33 2885-2889 UBERON:0000104 denotes life
T34 3007-3015 CHEBI:60004;CHEBI:60004 denotes mixtures
T35 3142-3148 GO:0016265 denotes deaths
T36 3303-3309 GO:0016265 denotes deaths
T37 3436-3442 UBERON:0000479 denotes tissue
T38 3455-3472 GO:0051866 denotes cellular adaptive
T39 3501-3507 UBERON:0000479;GO:0001894 denotes tissue
T40 3508-3519 GO:0001894 denotes homeostasis
T41 3552-3561 GO:0002437 denotes responses
T42 3596-3607 GO:0000075 denotes checkpoints
T43 3836-3852 CHEBI:67079;CHEBI:67079 denotes pro-inflammatory
T44 3853-3862 CHEBI:36357;CHEBI:36357 denotes molecules
T45 4018-4025 GO:0006952 denotes defence
T46 4094-4102 CHEBI:75958;CHEBI:75958 denotes solution
T47 4172-4179 UBERON:0000479 denotes tissues
T48 4209-4222 GO:0065007 denotes dysregulation
T49 4262-4278 PR:000013428 denotes cyclooxygenase-2
T50 4280-4285 PR:000013428 denotes COX-2
T51 4288-4338 PR:000002089 denotes signal transducer and activator of transcription 3
T52 4340-4345 PR:000002089 denotes STAT3
T53 4348-4354 GO:0031012;PR:000010491 denotes matrix
T54 4355-4374 PR:000010491 denotes metalloproteinase-9
T55 4376-4381 PR:000010491 denotes MMP-9
T56 4408-4410 GO:0005883 denotes NF
T57 4473-4477 PR:000001393 denotes IL-6
T58 4479-4483 PR:000001395 denotes IL-8
T59 4516-4521 PR:000000134 denotes TNF-α
T60 4538-4547 CHEBI:36357;CHEBI:36357 denotes molecules
T61 4690-4703 CHEBI:67079;CHEBI:67079 denotes -inflammatory
T62 4704-4713 CHEBI:36357;CHEBI:36357 denotes molecules
T63 4760-4772 CHEBI:67079;CHEBI:67079 denotes inflammatory
T64 4791-4800 CHEBI:36357;CHEBI:36357 denotes molecules
T65 4966-4988 CHEBI:52217;CHEBI:52217 denotes pharmacological agents
T66 5127-5133 GO:0016265 denotes deaths
T67 5202-5208 NCBITaxon:33208 denotes animal
T68 5220-5225 SP_6;NCBITaxon:9606 denotes human
T69 5499-5501 GO:0005883 denotes NF
T70 5526-5529 PR:Q9FJR1 denotes p65
T71 5534-5537 PR:Q43731 denotes p50
T72 5567-5571 PR:000003293 denotes IκBα
T73 5612-5621 GO:0005737 denotes cytoplasm
T74 5690-5694 PR:000001395 denotes IL-8
T75 5696-5701 PR:000001136 denotes IL-1β
T76 5703-5707 PR:000001393 denotes IL-6
T77 5712-5717 PR:000000134 denotes TNF-α
T78 5767-5771 PR:000003293 denotes IκBα
T79 5809-5812 PR:Q43731 denotes p50
T80 5817-5820 PR:Q9FJR1 denotes p65
T81 5843-5850 GO:0005634 denotes nucleus
T82 5863-5871 SO:0000167 denotes promoter
T83 5895-5900 SO:0000704 denotes genes
T84 6002-6014 GO:0001525 denotes angiogenesis
T85 6041-6046 SO:0000704 denotes genes
T86 6047-6056 GO:0065007 denotes regulated
T87 6060-6062 GO:0005883 denotes NF
T88 6087-6097 GO:0010467 denotes expression
T89 6101-6106 PR:000000134 denotes TNF-α
T90 6108-6113 PR:000013428 denotes COX-2
T91 6115-6120 PR:000010491 denotes MMP-9
T92 6122-6134 CHEBI:16480;CHEBI:16480 denotes nitric oxide
T93 6190-6194 PR:000001393 denotes IL-6
T94 6199-6203 PR:000001395 denotes IL-8
T95 6240-6251 UBERON:0001986 denotes endothelial
T96 6267-6271 PR:000017284 denotes VEGF
T97 6287-6292 SO:0000704 denotes genes
T98 6356-6365 MOP:0000568 denotes oxidative
T99 6554-6556 GO:0005883 denotes NF
T100 6618-6634 GO:0007623 denotes circadian rhythm
T101 6644-6649 GO:0007568 denotes aging
T102 6675-6681 NCBITaxon:33208 denotes animal
T103 6843-6847 SO:0000704;GO:0010467 denotes gene
T104 6848-6858 GO:0010467 denotes expression
T105 6953-6968 GO:0007623 denotes circadian clock
T106 7083-7088 PR:000002089 denotes STAT3
T107 7092-7101 GO:0005737 denotes cytoplasm
T108 7136-7141 PR:000009196 denotes JAK 1
T109 7224-7229 PR:000002089 denotes STAT3
T110 7242-7249 GO:0005634 denotes nucleus
T111 7322-7344 CHEBI:67079;CHEBI:67079 denotes inflammatory mediators
T112 7406-7413 CHEBI:52290;CHEBI:52290 denotes mitogen
T113 7491-7494 PR:000008220 denotes p38
T114 7503-7506 PR:000009232 denotes Jun
T115 7536-7549 GO:0005576 denotes extracellular
T116 7745-7752 GO:0005634;PR:000011170 denotes nuclear
T117 7753-7759 PR:000011170 denotes factor
T118 7760-7769 PR:000011170;CL:0000764 denotes erythroid
T119 7770-7788 PR:000011170 denotes 2-related factor 2
T120 7790-7794 PR:000011170 denotes Nrf2
T121 7797-7816 PR:000009232 denotes activator protein-1
T122 7825-7832 GO:0005634 denotes nuclear
T123 7843-7852 CL:0002627 denotes activated
T124 7853-7860 CL:0000084 denotes T cells
T125 7871-7898 PR:000008555 denotes hypoxia-inducible factor-1α
T126 7900-7906 PR:000008555 denotes HIF-1α
T127 8144-8149 PR:000009277 denotes Keap1
T128 8152-8187 PR:000009277 denotes Kelch-like ECH-associated protein 1
T129 8189-8193 PR:000006048 denotes Cul3
T130 8196-8204 PR:000006048 denotes Cullin 3
T131 8206-8210 PR:000011170 denotes Nrf2
T132 8213-8220 GO:0005634;PR:000011170 denotes Nuclear
T133 8221-8227 PR:000011170 denotes factor
T134 8228-8237 PR:000011170;CL:0000764 denotes erythroid
T135 8238-8256 PR:000011170 denotes 2-related factor 2
T136 8264-8274 PR:000001775 denotes IκB kinase
T137 8276-8278 GO:0005883 denotes NF
T138 8317-8325 SO:0000165 denotes enhancer
T139 8329-8338 CL:0002627 denotes activated
T140 8339-8346 CL:0000236 denotes B cells
T141 8374-8377 PR:Q43731 denotes p50
T142 8379-8382 PR:Q9FJR1 denotes p65
T143 8387-8391 PR:000003293 denotes IkBα
T144 8402-8407 PR:000002089 denotes STAT3
T145 8410-8460 PR:000002089 denotes Signal transducer and activator of transcription 3
T146 8473-8480 CHEBI:52290;CHEBI:52290 denotes mitogen
T147 8658-8661 PR:000009232 denotes AP1
T148 8664-8683 PR:000009232 denotes Activator protein 1
T149 8758-8761 PR:000010045 denotes Maf
T174 8842-8852 GO:0065007;CL:0000815 denotes regulatory
T175 8853-8857 CL:0000815 denotes cell
T176 8892-8902 PR:000001775 denotes IκB kinase
T177 8915-8923 MOP:0000780 denotes cleavage
T178 8927-8929 GO:0005883 denotes NF
T179 8950-8957 GO:0005634;GO:0051169 denotes nuclear
T180 8958-8971 GO:0051169 denotes translocation
T181 8976-8979 PR:Q43731 denotes p50
T182 8984-8987 PR:Q9FJR1 denotes p65
T183 9039-9042 PR:000008220 denotes p38
T184 9078-9090 GO:0046983 denotes dimerization
T185 9094-9099 PR:000002089 denotes STAT3
T186 9229-9233 SO:0000704;GO:0010467 denotes gene
T187 9234-9244 GO:0010467 denotes expression
T188 9260-9272 CHEBI:67079;CHEBI:67079 denotes inflammatory
T189 9273-9282 CHEBI:36357;CHEBI:36357 denotes molecules
T190 9306-9316 GO:0010467 denotes expression
T191 9391-9395 PR:000011170 denotes Nrf2
T192 9428-9435 GO:0005634 denotes nuclear
T193 9543-9551 GO:0044237 denotes cellular
T194 9556-9565 GO:0008152 denotes metabolic
T195 9683-9692 GO:0008152 denotes metabolic
T196 9776-9780 UBERON:0000104 denotes life
T197 10200-10207 PR:000009054 denotes insulin
T198 10220-10234 UBERON:0001013 denotes Adipose tissue
T199 10322-10331 CL:0000136 denotes adipocyte
T200 10390-10404 UBERON:0001013 denotes adipose tissue
T201 10414-10425 CL:0000864 denotes macrophages
T202 10562-10575 CL:0002334 denotes preadipocytes
T203 10605-10620 CL:0000445 denotes apoptotic cells
T204 10622-10634 GO:0001525 denotes angiogenesis
T205 10670-10684 UBERON:0001013 denotes adipose tissue
T206 10766-10772 PR:000008555 denotes HIF-1α
T207 10806-10815 CL:0000576 denotes monocytes
T208 10877-10888 CL:0000863 denotes macrophages
T209 10911-10916 PR:000000134 denotes TNF-α
T210 10918-10926 CL:0000576 denotes monocyte
T211 10948-10953 PR:000002122 denotes MCP-1
T212 10968-10972 PR:000001395 denotes IL-8
T213 11054-11064 CL:0000136 denotes adipocytes
T214 11075-11084 CL:0000136 denotes adipocyte
T215 11109-11120 CHEBI:35366;CHEBI:35366 denotes fatty acids
T216 11160-11176 CHEBI:26523;CHEBI:26523 denotes reactive species
T217 11386-11395 GO:0008152 denotes Metabolic
T218 11465-11487 CHEBI:67079;CHEBI:67079 denotes inflammatory mediators
T219 11489-11494 PR:000001376 denotes IL-18
T220 11496-11501 PR:000001136 denotes IL-1β
T221 11557-11572 GO:0051260 denotes oligomerization
T222 11573-11579 SO:0000417 denotes domain
T223 11609-11614 PR:000010313 denotes pyrin
T224 11615-11621 SO:0000417 denotes domain
T225 11636-11641 PR:000011271 denotes NLRP3
T226 11657-11668 GO:0005737 denotes cytoplasmic
T227 11669-11676 GO:0032991 denotes complex
T228 11690-11695 PR:000011271 denotes NLRP3
T229 11722-11732 GO:0065007 denotes modulating
T230 11752-11765 UBERON:0002405 denotes immune system
T231 11905-11912 CHEBI:17234;CHEBI:17234 denotes glucose
T232 11956-11961 PR:000001376 denotes IL-18
T233 11973-11978 PR:000001136 denotes IL-1β
T234 12043-12045 GO:0005883;GO:0051092 denotes NF
T235 12045-12059 GO:0051092 denotes -κB activation
T236 12365-12375 GO:0010467 denotes expression
T237 12379-12391 CHEBI:35472;CHEBI:35472 denotes inflammatory
T238 12392-12401 CHEBI:36357;CHEBI:36357 denotes molecules
T239 12524-12533 GO:0008152 denotes metabolic
T240 12602-12615 GO:0005576 denotes extracellular
T241 12616-12624 GO:0031012 denotes matrices
T242 12626-12630 GO:0031012 denotes ECMs
T243 12689-12702 CL:0000630 denotes support cells
T244 12706-12713 UBERON:0000479 denotes tissues
T245 12722-12732 GO:0065007 denotes regulatory
T246 12745-12765 GO:0008150 denotes biological processes
T247 12781-12787 UBERON:0000479 denotes tissue
T248 12820-12824 GO:0044420 denotes ECMs
T249 12864-12877 CHEBI:37396;CHEBI:37396 denotes proteoglycans
T250 12890-12908 CHEBI:18085;CHEBI:18085 denotes glycosaminoglycans
T251 12935-12942 SO:0000417 denotes modules
T252 12959-12962 GO:0044420 denotes ECM
T253 13102-13113 GO:0042592 denotes homeostasis
T254 13291-13294 GO:0044420 denotes ECM
T255 13323-13332 CHEBI:67079;CHEBI:67079 denotes mediators
T256 13477-13480 GO:0044420 denotes ECM
T257 13494-13500 UBERON:0000479 denotes tissue
T258 13562-13568 UBERON:0000479 denotes tissue
T259 13659-13662 GO:0044420 denotes ECM
T260 13678-13687 GO:0008152 denotes metabolic
T261 13837-13851 UBERON:0001013 denotes adipose tissue
T262 13852-13855 GO:0044420 denotes ECM
T263 13873-13885 GO:0065007 denotes dysregulated
T264 13886-13899 GO:0005622;GO:0035556 denotes intracellular
T265 13900-13910 GO:0035556 denotes signalling
T266 13963-13970 PR:000009054 denotes insulin
T267 14033-14047 UBERON:0001013 denotes adipose tissue
T268 14048-14051 GO:0044420 denotes ECM
T269 14067-14078 PR:000007581 denotes fibronectin
T270 14139-14150 PR:000015561 denotes osteopontin
T271 14239-14245 SO:0000417 denotes domain
T272 14306-14309 GO:0044420 denotes ECM
T273 14330-14340 GO:0065007 denotes regulation
T274 14344-14358 UBERON:0001013 denotes adipose tissue
T275 14442-14447 CHEBI:18059;CHEBI:18059 denotes lipid
T276 14448-14454 UBERON:0000479 denotes tissue
T277 14503-14513 CL:0000136 denotes adipocytes
T278 14552-14562 CL:0000136 denotes adipocytes
T279 14586-14598 GO:0060612 denotes adipogenesis
T280 14614-14624 CL:0000034 denotes stem cells
T281 14685-14688 GO:0044420 denotes ECM
T282 14731-14740 GO:0065007 denotes regulates
T283 14741-14753 GO:0060612 denotes adipogenesis
T284 14792-14801 CL:0000136 denotes adipocyte
T285 14824-14836 GO:0042116 denotes migration of
T286 14837-14848 CL:0000235 denotes macrophages
T287 14853-14867 CL:0000071 denotes vascular cells
T288 14901-14904 GO:0044420 denotes ECM
T289 14964-14973 CHEBI:67079;CHEBI:67079 denotes mediators
T290 14990-14996 UBERON:0002405;CL:0000738 denotes immune
T291 14997-15002 CL:0000738 denotes cells
T292 15071-15076 CHEBI:18059;CHEBI:18059 denotes lipid
T293 15077-15083 UBERON:0000479 denotes tissue
T294 15131-15145 UBERON:0001013 denotes adipose tissue
T295 15146-15160 GO:0044420 denotes ECM components
T296 15186-15197 PR:000015561 denotes osteopontin
T297 15241-15251 CL:0000136 denotes adipocytes
T298 15281-15287 UBERON:0002405;CL:0000738 denotes immune
T299 15288-15293 CL:0000738 denotes cells
T300 15306-15312 UBERON:0000479 denotes tissue
T301 15330-15339 GO:0008152 denotes metabolic
T302 15411-15425 GO:0010467 denotes overexpression
T303 15460-15468 MOP:0000780 denotes cleavage
T304 15502-15508 PR:000003341 denotes Col6a3
T305 15573-15587 UBERON:0001013 denotes adipose tissue
T306 15605-15612 PR:000009054 denotes insulin
T307 15681-15691 GO:0010467 denotes expression
T308 15695-15700 PR:000010474 denotes MMP14
T309 15732-15746 UBERON:0001013 denotes adipose tissue
T310 15767-15771 NCBITaxon:10088 denotes mice
T311 15788-15793 PR:000010474 denotes MMP14
T312 15794-15805 GO:0006508 denotes proteolytic
T313 15891-15901 CL:0000136 denotes adipocytes
T314 15939-15944 CHEBI:18059;CHEBI:18059;GO:0006629 denotes lipid
T315 15945-15955 GO:0006629 denotes metabolism
T316 15960-15967 PR:000009054 denotes insulin
T317 16083-16086 GO:0044420 denotes ECM
T318 16106-16112 UBERON:0000310 denotes breast
T319 16136-16150 UBERON:0001013 denotes adipose tissue
T320 16151-16163 UBERON:0005169 denotes interstitial
T321 16214-16225 CL:0000235 denotes macrophages
T322 16271-16282 CL:0000235 denotes macrophages
T323 16392-16401 GO:0038001 denotes paracrine
T324 16426-16437 CHEBI:35366;CHEBI:35366 denotes fatty acids
T325 16442-16447 PR:000000134 denotes TNF-α
T326 16469-16479 CL:0000136 denotes adipocytes
T327 16497-16508 CL:0000235 denotes macrophages
T328 16564-16578 UBERON:0001013 denotes adipose tissue
T329 16634-16646 CHEBI:37396;CHEBI:37396 denotes proteoglycan
T330 16690-16703 GO:0010467 denotes overexpressed
T331 16707-16710 GO:0044420 denotes ECM
T332 16714-16726 UBERON:0002190 denotes subcutaneous
T333 16727-16730 UBERON:0001013 denotes fat
T334 16734-16741 PR:000009054 denotes insulin
T335 16758-16769 NCBITaxon:1 denotes individuals
T336 16837-16848 GO:0065007 denotes dysregulate
T337 16849-16861 GO:0060612 denotes adipogenesis
T338 16874-16883 MOP:0000568 denotes oxidative
T339 16941-16948 PR:000009054 denotes insulin
T340 17076-17090 UBERON:0001013 denotes adipose tissue
T341 17147-17150 GO:0044420 denotes ECM
T342 17207-17210 GO:0044420 denotes ECM
T343 17216-17223 CHEBI:17234;CHEBI:17234;GO:0042593 denotes glucose
T344 17224-17235 GO:0042593 denotes homeostasis
T345 17244-17253 GO:0008152 denotes metabolic
T346 17285-17296 PR:000015561 denotes Osteopontin
T347 17301-17304 GO:0044420 denotes ECM
T348 17305-17317 CHEBI:17089;BV_11;CHEBI:17089 denotes glycoprotein
T349 17331-17339 GO:0046903 denotes secreted
T350 17343-17357 UBERON:0001013 denotes adipose tissue
T351 17358-17369 CL:0000235 denotes macrophages
T352 17403-17417 UBERON:0001013 denotes adipose tissue
T353 17460-17467 PR:000009054 denotes insulin
T354 17520-17533 GO:0044420 denotes ECM component
T355 17539-17556 CHEBI:18085;CHEBI:18085 denotes glycosaminoglycan
T356 17862-17870 GO:0032940 denotes secreted
T357 17899-17905 UBERON:0000479 denotes tissue
T358 18252-18272 PR:000001155 denotes Toll-like receptor 4
T359 18274-18278 PR:000001155 denotes TLR4
T360 18280-18282 GO:0005883 denotes NF
T361 18308-18316 GO:0065007 denotes regulate
T362 18330-18335 SO:0000704 denotes genes
T363 18353-18359 UBERON:0002405;CL:0000738 denotes immune
T364 18360-18365 CL:0000738 denotes cells
T365 18462-18469 UBERON:0000479 denotes tissues
T366 18559-18576 GO:0042593 denotes glycaemic control
T367 18818-18828 GO:0010467 denotes expression
T368 18832-18837 SO:0000704 denotes genes
T369 18854-18864 GO:0008152 denotes metabolism
T370 18865-18870 GO:0009081 denotes of HA
T371 18915-18924 CL:0000136 denotes adipocyte
T372 19043-19058 GO:0060612 denotes adipogenesis of
T373 19109-19116 PR:000009054 denotes insulin
T374 19173-19182 UBERON:0007808 denotes abdominal
T375 19183-19186 UBERON:0001013 denotes fat
T376 19194-19201 GO:0007631 denotes feeding
T377 19211-19216 NCBITaxon:10088 denotes mouse
T378 19269-19272 GO:0007631 denotes fed
T379 19279-19283 NCBITaxon:10088 denotes mice
T380 19312-19319 GO:0032991 denotes complex
T381 19327-19332 SP_6;NCBITaxon:9606 denotes human
T382 19408-19422 UBERON:0001013 denotes adipose tissue
T383 19440-19447 PR:000009054 denotes insulin
T384 19494-19503 GO:0008152 denotes metabolic
T385 19528-19531 CHEBI:13389;CHEBI:13389 denotes NAD
T386 19531-19532 CHEBI:15846;CHEBI:15846 denotes +
T387 19567-19575 CHEBI:10545;CHEBI:10545;MOP:0000615 denotes electron
T388 19576-19582 MOP:0000615 denotes supply
T389 19589-19602 GO:0065007 denotes dysregulation
T390 19625-19638 GO:0005739 denotes mitochondrial
T391 19663-19669 PR:000029756 denotes SIRT-3
T392 19697-19706 MOP:0000568 denotes oxidative
T393 19728-19738 CHEBI:35366;CHEBI:35366 denotes fatty acid
T394 19741-19750 MOP:0000568 denotes oxidation
T395 19789-19803 GO:1903409 denotes ROS production
T396 19853-19856 GO:0044420 denotes ECM
T397 19914-19923 MOP:0000568 denotes oxidative
T398 19947-19954 CHEBI:17234;CHEBI:17234 denotes glucose
T399 19966-19969 NCBITaxon:10114 denotes rat
T400 19970-19980 CL:1000742 denotes glomerular
T401 19981-19990 CL:1000742;UBERON:0003104 denotes mesangial
T402 19991-19996 CL:1000742 denotes cells
T403 20053-20064 PR:000007581 denotes fibronectin
T404 20097-20102 PR:000016867 denotes TXNIP
T405 20103-20108 PR:000011271 denotes NLRP3
T406 20109-20132 GO:0035556 denotes inflammasome signalling
T407 20186-20191 UBERON:0002113 denotes renal
T408 20192-20195 GO:0044420 denotes ECM
T409 20389-20405 CHEBI:50488;CHEBI:50488 denotes dihydroquercetin
T410 20479-20484 PR:000011271 denotes NLRP3
T411 20544-20547 GO:0044420 denotes ECM
T412 20551-20556 UBERON:0002113 denotes renal
T413 20603-20608 UBERON:0002113;CL:1000497 denotes renal
T414 20609-20614 CL:1000497 denotes cells
T415 20623-20630 CHEBI:17234;CHEBI:17234 denotes glucose
T416 20717-20720 GO:0044420 denotes ECM
T417 20740-20749 GO:0008152 denotes metabolic
T418 20786-20789 GO:0044420 denotes ECM
T419 20801-20804 GO:0044420 denotes ECM
T420 21032-21044 CHEBI:16646;CHEBI:16646 denotes Carbohydrate
T421 21145-21148 CHEBI:26523;CHEBI:26523 denotes ROS
T422 21194-21196 GO:0005883 denotes NF
T423 21221-21231 GO:0010467 denotes expression
T424 21238-21251 CHEBI:67079;CHEBI:67079 denotes -inflammatory
T425 21252-21261 CHEBI:36357;CHEBI:36357 denotes molecules
T426 21270-21275 PR:000002122 denotes MCP-1
T427 21277-21282 PR:000000134 denotes TNF-α
T428 21284-21288 PR:000001393 denotes IL-6
T429 21290-21295 PR:000001136 denotes IL-1β
T430 21303-21307 PR:000009232 denotes AP-1
T431 21332-21341 CHEBI:36357;CHEBI:36357 denotes molecules
T432 21361-21368 PR:000009054 denotes insulin
T433 21400-21407 PR:000009054 denotes insulin
T434 21484-21489 UBERON:0000178 denotes blood
T435 21639-21648 GO:0006096 denotes glycaemic
T436 21655-21659 CHEBI:33290;CHEBI:33290 denotes food
T437 21776-21788 CHEBI:35472;CHEBI:35472 denotes inflammatory
T438 21789-21798 CHEBI:36357;CHEBI:36357 denotes molecules
T439 21896-21908 CHEBI:16646;CHEBI:16646 denotes carbohydrate
T440 21909-21915 GO:0007631 denotes intake
T441 21962-21970 UBERON:0000104 denotes lifespan
T442 21991-21995 NCBITaxon:10088 denotes mice
T443 22008-22012 PR:000001393 denotes IL-6
T444 22019-22022 PR:000001136 denotes -1β
T445 22096-22101 UBERON:0001977 denotes serum
T446 22102-22109 CHEBI:17234;CHEBI:17234 denotes glucose
T447 22113-22120 PR:000009054 denotes insulin
T448 22189-22201 CHEBI:16646;CHEBI:16646 denotes carbohydrate
T449 22291-22298 CHEBI:17234;CHEBI:17234;GO:0006006 denotes glucose
T450 22346-22351 CHEBI:18059;CHEBI:18059;GO:0006629 denotes lipid
T451 22352-22362 GO:0006629 denotes metabolism
T452 22396-22401 UBERON:0002107 denotes liver
T453 22428-22438 UBERON:0001264 denotes pancreatic
T454 22499-22505 GO:0007631 denotes intake
T455 22554-22567 CHEBI:35472;CHEBI:35472 denotes -inflammatory
T456 22568-22577 CHEBI:36357;CHEBI:36357 denotes molecules
T457 22587-22592 PR:000001136 denotes IL-1β
T458 22669-22675 CHEBI:17087;CHEBI:17087 denotes ketone
T459 22676-22684 CHEBI:51307;CHEBI:51307 denotes diesters
T460 22722-22727 PR:000011271 denotes NLRP3
T461 22785-22796 UBERON:0002240 denotes spinal cord
T462 22807-22816 CHEBI:25754;CHEBI:25754;GO:0031424 denotes ketogenic
T463 22830-22839 MOP:0000568 denotes oxidative
T464 22888-22890 GO:0005883 denotes NF
T465 22958-22962 PR:000011170 denotes Nrf2
T466 22986-22991 PR:000000134 denotes TNF-α
T467 22993-22998 PR:000001136 denotes IL-1β
T468 23000-23005 PR:000000017 denotes IFN-γ
T469 23006-23016 GO:0010467 denotes expression
T607 23164-23170 GO:0007631 denotes intake
T797 23235-23236 UBERON:0001913 denotes i
T807 23271-23272 GO:0008152 denotes O
T810 23282-23283 CHEBI:36357;CHEBI:36357 denotes e
T816 23305-23307 CHEBI:67079;CHEBI:67079 denotes -o
T818 23314-23315 GO:0007259 denotes a
T837 23317-23319 PR:Q43731 denotes 50
T840 23321-23322 PR:000002089 denotes a
T859 23329-23330 GO:0008152 denotes b
T874 23332-23333 PR:000013428 denotes c
T876 23333-23334 PR:000000134 denotes t
T889 23346-23349 UBERON:0004535 denotes ris
T890 23354-23355 UBERON:0001977 denotes m
T895 23369-23370 GO:0010467 denotes o
T902 23384-23386 GO:0010467 denotes pe
T907 23387-23388 PR:000001776 denotes i
T908 23393-23395 CHEBI:26607;CHEBI:26607 denotes f
T909 23397-23398 CHEBI:16646;CHEBI:16646 denotes o
T910 23399-23400 GO:0010467 denotes e
T911 23401-23402 SO:0000704 denotes g
T918 23415-23416 PR:000001136 denotes 1
T994 23446-23447 CHEBI:50488;CHEBI:50488 denotes m
T996 23447-23448 CHEBI:28661;CHEBI:28661 denotes a
T1199 23459-23461 PR:000001417 denotes 10
T1202 23462-23463 CL:0000235 denotes g
T1234 23469-23470 GO:0005883;GO:0051092 denotes f
T1235 23470-23471 GO:0051092 denotes
T1247 23496-23497 UBERON:0000010 denotes a
T1257 23500-23501 CHEBI:28757;CHEBI:28757 denotes s
T1264 23508-23509 UBERON:0002107 denotes r
T1267 23513-23514 GO:0065007 denotes o
T1342 23523-23524 GO:0010467 denotes s
T1348 23529-23530 NCBITaxon:10088 denotes o
T1355 23534-23535 NCBITaxon:10088 denotes e
T1356 23535-23536 PR:000001092 denotes i
T1372 23537-23538 SP_6;NCBITaxon:9606 denotes h
T1382 23542-23544 GO:0010467 denotes er
T1396 23561-23562 CHEBI:16856;CHEBI:16856 denotes a
T1405 23566-23567 GO:0005777 denotes s
T1461 23582-23583 CHEBI:30751;CHEBI:30751 denotes a
T2012 23855-23858 GO:0007631 denotes in,
T2013 23863-23873 CHEBI:5086;CHEBI:5086 denotes Vulevic et
T2014 23874-23877 CHEBI:35218;CHEBI:35218 denotes al.
T2015 23889-23894 CHEBI:24043;CHEBI:24043 denotes omize
T2016 23896-23900 GO:0007631 denotes cont
T2017 23941-23947 PR:000009054 denotes ic syn
T2018 23962-23972 CHEBI:35218;CHEBI:35218 denotes of rye and
T2019 23973-23978 GO:0007631 denotes whole
T2021 24050-24052 GO:0007631 denotes ne
T2023 24225-24234 GO:0008152 denotes metabolic
T2024 24348-24360 PR:000001393 denotes calprotectin
T2025 24430-24452 CHEBI:26195;CHEBI:26195 denotes hypercholesterolemic s
T2026 24618-24622 UBERON:0000178 denotes lled
T2027 24701-24713 PR:000009054 denotes (RS2) versus
T2028 24717-24727 PR:000009054 denotes isocaloric
T2029 24790-24791 UBERON:0001969 denotes s
T2031 25239-25241 CHEBI:36357;CHEBI:36357 denotes or
T2032 25268-25279 UBERON:0004535 denotes to American
T2033 25457-25459 UBERON:0007023 denotes at
T2034 25597-25602 CHEBI:16113;CHEBI:16113 denotes white
T2035 25603-25607 CHEBI:17855;CHEBI:17855 denotes rice
T2036 25611-25621 CHEBI:12071;CHEBI:12071 denotes = 14) diet
T2037 25792-25801 CHEBI:21241;CHEBI:21241 denotes Diet (n =
T2038 25809-25820 CHEBI:26195;CHEBI:26195 denotes whole-grain
T2039 25827-25829 CHEBI:33290;CHEBI:33290 denotes ed
T2040 25862-25884 GO:0008152 denotes 45) diet, Healthy Diet
T2041 25917-25932 CHEBI:39015;CHEBI:39015 denotes and whole grain
T2043 25947-25948 PR:000001415 denotes e
T2044 26013-26028 CHEBI:26195;CHEBI:26195 denotes double-blind, s
T2045 26112-26120 GO:0008152 denotes mentable
T2046 26454-26467 MOP:0000568 denotes d fatty acids
T2047 26507-26511 PR:000001393 denotes IL-6
T2048 26852-26857 PR:000004155 denotes patie
T2049 26879-26894 CHEBI:16243;CHEBI:16243 denotes either resistan
T2050 26977-26985 CHEBI:16243;CHEBI:16243 denotes (2018) R
T2051 27085-27086 UBERON:0000178 denotes o
T2052 27538-27544 UBERON:0000178 denotes bre or
T2053 27759-27766 CHEBI:16412;CHEBI:16412 denotes periods
T2054 27833-27835 PR:000001395 denotes IL
T2055 27835-27838 PR:000001395;GO:1990774 denotes -10
T2058 28120-28160 PR:000009054 denotes inical trial 60 females with T2DM Patien
T2059 28251-28304 GO:0008152 denotes on IL-6 or CRP Gargari et al. (2015) Crossover clinic
T2060 28546-28595 SO:0000704 denotes et al. (2018) Observational study 49 T2DM females
T2061 28630-28636 PR:000009054 denotes inulin
T2062 28884-28909 CHEBI:47916;CHEBI:47916 denotes for 8 weeks oligofructose
T2063 29301-29314 CHEBI:47916;CHEBI:47916 denotes flammation. D
T2064 29322-29333 GO:0007631 denotes ies Treatme
T2065 29590-29644 CHEBI:33290;CHEBI:33290 denotes fatty acids He et al. (2019) Scandinavian low-carbohyd
T2066 29810-29834 PR:000009054 denotes in glycemia, TG, insulin
T2067 30166-30252 CHEBI:35218;CHEBI:35218 denotes Control: standard chow ➢ Ketogenic diet group KD: ↑ triglycerides, cholesterol, leptin
T2068 30282-30303 CHEBI:24043;CHEBI:24043 denotes β-cell mass Ellenbroe
T2069 30305-30321 GO:0007631 denotes et al. (2014) Ke
T2070 30668-30703 PR:000009054 denotes intolerance, steatosis, cellular in
T2071 31215-31259 GO:0007631 denotes Control: normal chow with 4.5% fat ➢ Study g
T2072 31306-31320 CHEBI:35218;CHEBI:35218 denotes anediol ketone
T2074 31630-31636 CHEBI:16412;CHEBI:16412 denotes expres
T2075 32020-32055 CHEBI:26195;CHEBI:26195 denotes type of carbohydrates and fats cons
T2076 33243-33260 GO:0008152 denotes et al., 2013). In
T2077 33387-33414 CHEBI:26195;CHEBI:26195 denotes portantly, these beneficial
T2078 33717-33728 CHEBI:26195;CHEBI:26195 denotes adolescents
T2079 34956-35000 CHEBI:26195;CHEBI:26195 denotes (LFD), ➢ followed by 12 weeks of high intens
T2080 35254-35291 UBERON:0001969 denotes (2018) Low-carbohydrate versus low-fa
T2082 35402-35448 MOP:0000568 denotes ow-fat diet (LFD) LCD: ↓ sICAM, E-selectinLFD:
T2083 35540-35596 UBERON:0001088 denotes 51 T2DM patients 6-month diet intervention:➢ Low-carbohy
T2084 35602-35619 CHEBI:35515;CHEBI:35515 denotes diet (LCD) ➢ Low-
T2085 35624-35673 CHEBI:30362;CHEBI:30362 denotes iet (LFD) LCD: ↓ IL-1Ra, IL-6 Johansson-Persson e
T2086 35864-35966 CHEBI:26195;CHEBI:26195 denotes diet – LFD, n = 73 (<30% kcal/day from total fat, <7% saturated fat) LCD: ↑ adiponectin ↓ICAM Hu et al
T2087 36198-36227 CHEBI:26195;CHEBI:26195 denotes proved glycaemic profile vers
T2088 36452-36483 CHEBI:16113;CHEBI:16113 denotes calorie (LC) diet, ➢ Group 2: L
T2089 37604-37692 CHEBI:26195;CHEBI:26195 denotes diet (LFHC) group HFLC: ↓ CRP,TG ↑ adiponectin, HDL Ruth et al. (2013) Nutritional ketos
T2090 37760-37794 GO:0008152 denotes intervention:➢ Nutritional ketosis
T2091 37795-37799 GO:0009081 denotes (NK,
T2092 37800-37801 CHEBI:29021;CHEBI:29021 denotes n
T2093 37865-37893 UBERON:0000178 denotes al. (2018) Moderate-carbohyd
T2094 38538-38542 CHEBI:51231;CHEBI:51231 denotes from
T2095 38599-38713 CHEBI:35218;CHEBI:35218 denotes aemic-index diet (LGI) (60% from carbohydrate, 25% from fat, and 15% from protein) ➢ LGI, rich in functional foods
T2096 38831-38857 CHEBI:15956;CHEBI:15956 denotes LGI: ↑ adiponectin Izadi e
T2097 38906-38916 CHEBI:33290;CHEBI:33290 denotes controlled
T2098 38992-38999 UBERON:0001977 denotes Healthy
T2099 39002-39030 CHEBI:17855;CHEBI:17855 denotes tritional recommendation die
T2100 39982-40008 CHEBI:26267;CHEBI:26267 denotes parative study 28 patients
T2101 40124-40128 GO:0007631 denotes ICAM
T2102 40139-40198 CHEBI:26195;CHEBI:26195 denotes of insulin and sICAM persistent, while CRP did not when res
T2103 40461-40509 CHEBI:26195;CHEBI:26195 denotes effects on inflammatory profile of T2DM and obes
T2104 41003-41045 GO:0008152 denotes med in moderate amounts, as is wine (espec
T2105 41127-41143 SP_7 denotes al., 2014; Tosti
T2106 41144-41163 GO:0008152 denotes et al., 2018). This
T2107 41342-41350 SP_7 denotes combined
T2108 41385-41419 UBERON:0001004 denotes reducing the systemic inflammatory
T2109 41608-41688 SP_7 denotes sses equilibrium (Martucci et al., 2017). Epigenetic regulation was also hypothe
T2110 41695-41712 SP_7;UBERON:0001004 denotes especially due to
T2111 41722-41818 SP_7 denotes s found in nuts and extra virgin olive oil, which were reported to alter the methylation of some
T2112 41823-41835 SP_7 denotes s related to
T2113 42715-42742 UBERON:0005169 denotes interleukins production via
T2114 43157-43177 UBERON:0000062 denotes or kappa-light-chain
T2116 44339-44344 SP_7 denotes ratio
T2117 45289-45312 SP_7 denotes coenzyme Q10 (MD-Q10) ➢
T2118 45347-45350 NCBITaxon:1 denotes ids
T2119 45697-45699 UBERON:0002405;GO:0006955 denotes in
T2120 45732-45739 GO:0006955 denotes ression
T2121 45743-45744 NCBITaxon:10239 denotes i
T2122 45938-45963 GO:0008152 denotes periods of 4 weeks in a c
T2123 46162-46199 SP_7 denotes (KMD-O3) KMD: ↓ TNF-αKMD-O3: ↓ IL-1β,
T2124 46388-46414 GO:0065007;CL:0000815 denotes RP (versus baseline) Tripp
T2125 46416-46437 CL:0000815 denotes t al. (2019) Clinical
T2128 47012-47063 NCBITaxon:1 denotes il Low fat diet (LFD) MD: ↓ IL-6, ICAM-1, ↑ GLP-1 s
T2129 47210-47212 UBERON:0002405;CL:0000738 denotes ie
T2130 47214-47219 CL:0000738 denotes (LFD)
T2131 47382-47421 CHEBI:67079;CHEBI:67079 denotes diet (LFD) ↓ dietary inflammatory index
T2132 47433-47438 PR:000001393 denotes IL-1b
T2133 47459-47464 PR:000000134 denotes TNF-α
T2134 47495-47510 CL:0000235;PR:000002123 denotes mized Controlle
T2135 47514-47589 PR:000002123 denotes ial 164 subjects with high cardiovascular risk 12-month diet intervention:➢
T2136 47827-47847 CHEBI:67079;CHEBI:67079 denotes of a diet similar to
T2137 47935-47945 UBERON:0001004;GO:0045333 denotes especially
T2138 47947-47975 UBERON:0000483 denotes erries, and vegetables, fish
T2139 48220-48273 SP_7 denotes reports are reviewed elsewhere (Lankinen et al., 2019
T2140 48615-48624 GO:0008152 denotes metabolic
T25 55683-55694 CHEBI:26195;CHEBI:26195 denotes Polyphenols
T2141 99501-99509 SP_7 denotes COVID-19
T2142 99767-99780 UBERON:0002405 denotes immune system
T62234 99767-99780 UBERON:0002405 denotes immune system
T2143 99869-99880 CHEBI:26195;CHEBI:26195 denotes polyphenols
T86339 99869-99880 CHEBI:26195;CHEBI:26195 denotes polyphenols
T2144 100027-100032 NCBITaxon:10239 denotes virus
T53424 100027-100032 NCBITaxon:10239 denotes virus
T2145 100137-100147 GO:0065007 denotes regulating
T82471 100137-100147 GO:0065007 denotes regulating
T2146 100239-100247 GO:0007631 denotes ingested
T24720 100239-100247 GO:0007631 denotes ingested
T2147 100441-100445 UBERON:0000104 denotes life
T90996 100441-100445 UBERON:0000104 denotes life
T33658 100441-100445 UBERON:0000104 denotes life
T2148 100556-100561 UBERON:0004905 denotes joint
T64396 100556-100561 UBERON:0004905 denotes joint
T2149 100582-100591 CHEBI:36357;CHEBI:36357 denotes molecules
T19892 100582-100591 CHEBI:36357;CHEBI:36357 denotes molecules
T2150 100638-100652 CHEBI:50733;CHEBI:50733 denotes nutraceuticals
T15009 100638-100652 CHEBI:50733;CHEBI:50733 denotes nutraceuticals
T2151 100665-100671 GO:0007631 denotes intake
T26033 100665-100671 GO:0007631 denotes intake
T2152 100751-100759 GO:0044237 denotes cellular
T58405 100751-100759 GO:0044237 denotes cellular
T2153 100764-100773 GO:0008152 denotes metabolic
T73290 100764-100773 GO:0008152 denotes metabolic
T2154 100793-100802 CHEBI:36357;CHEBI:36357 denotes compounds
T75044 100793-100802 CHEBI:36357;CHEBI:36357 denotes compounds
T2155 100941-100949 GO:0046959 denotes habitual
T61810 100941-100949 GO:0046959 denotes habitual
T2156 100950-100961 GO:0007631 denotes consumption
T78336 100950-100961 GO:0007631 denotes consumption
T2157 100976-100991 CHEBI:52217;CHEBI:52217 denotes pharmacological
T74982 100976-100991 CHEBI:52217;CHEBI:52217 denotes pharmacological
T2158 101319-101324 NCBITaxon:10239 denotes viral
T5787 101319-101324 NCBITaxon:10239 denotes viral
T2159 101419-101427 SP_7 denotes COVID-19
T48907 101419-101427 SP_7 denotes COVID-19
T2160 101428-101439 UBERON:0001004 denotes respiratory
T86218 101428-101439 UBERON:0001004 denotes respiratory
T2161 101655-101661 UBERON:0002405;GO:0006955 denotes immune
T22883 101655-101661 UBERON:0002405;GO:0006955 denotes immune
T2162 101662-101670 GO:0006955 denotes response
T47508 101662-101670 GO:0006955 denotes response