| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T168 |
0-4 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T169 |
5-9 |
PR:000036013 |
denotes |
Ang1 |
| T90424 |
15-20 |
PR:000000103 |
denotes |
Axis |
| T170 |
21-31 |
GO:0065007 |
denotes |
Regulation |
| T29796 |
31-37 |
PR:000036009 |
denotes |
Ang I |
| T171 |
32-37 |
PR:000036008 |
denotes |
Ang I |
| T172 |
94-100 |
PR:000036009 |
denotes |
Ang II |
| T98730 |
101-105 |
PR:000036013 |
denotes |
by A |
| T86736 |
112-116 |
PR:000003622;G_3;PG_10 |
denotes |
ike |
| T173 |
121-126 |
PR:000036008 |
denotes |
Ang I |
| T174 |
147-151 |
PR:000036012 |
denotes |
Ang1 |
| T175 |
157-161 |
PR:000003622;G_3;PG_10 |
denotes |
ACE2 |
| T89530 |
185-190 |
PR:000036013 |
denotes |
Ang |
| T176 |
186-192 |
PR:000036009 |
denotes |
Ang II |
| T177 |
209-214 |
PR:000036013 |
denotes |
Ang 1 |
| T178 |
225-229 |
PR:000003622;G_3;PG_10 |
denotes |
ACE2 |
| T48188 |
229-234 |
PR:000036008 |
denotes |
(17) |
| T179 |
236-241 |
PR:000036013 |
denotes |
Ang1- |
| T41061 |
254-260 |
PR:000036012 |
denotes |
of an |
| T180 |
258-275 |
CHEBI:67079;CHEBI:67079 |
denotes |
anti-inflammatory |
| T94791 |
298-308 |
PR:000001898 |
denotes |
tory, and |
| T37488 |
343-348 |
PR:000013883 |
denotes |
ed by |
| T309 |
386-390 |
G_3;PG_10;PR:000003622 |
denotes |
Mas |
| T181 |
387-390 |
PR:000001563 |
denotes |
Mas |
| T310 |
391-395 |
PR:000036013 |
denotes |
rece |
| T311 |
406-416 |
GO:0065007 |
denotes |
,27). Ang1 |
| T182 |
412-418 |
PR:000036013 |
denotes |
Ang1-7 |
| T312 |
417-432 |
CHEBI:2720;CHEBI:2720 |
denotes |
7 may be produc |
| T183 |
449-454 |
PR:000036008 |
denotes |
Ang I |
| T313 |
449-462 |
PR:000036008 |
denotes |
Ang I through |
| T314 |
464-469 |
PR:000036008 |
denotes |
he al |
| T315 |
475-480 |
PR:000013883 |
denotes |
ive p |
| T316 |
482-487 |
PR:000036008 |
denotes |
hways |
| T317 |
504-512 |
PR:000036009 |
denotes |
metallo |
| T184 |
522-532 |
PR:000001898 |
denotes |
neprilysin |
| T185 |
550-556 |
PR:000036012 |
denotes |
Ang1-9 |
| T186 |
560-566 |
PR:000036013 |
denotes |
Ang1-7 |
| T318 |
565-575 |
MOP:0000619 |
denotes |
7 via ACE, |
| T319 |
576-586 |
CHEBI:3165;CHEBI:3165 |
denotes |
although a |
| T320 |
605-614 |
CHEBI:25212;CHEBI:25212 |
denotes |
ower effi |
| T187 |
627-634 |
SO:0000704 |
denotes |
Genetic |
| T188 |
669-673 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T321 |
672-678 |
PR:000036009 |
denotes |
2 as a |
| T322 |
695-701 |
PR:000036009 |
denotes |
ator o |
| T189 |
703-717 |
UBERON:0004535 |
denotes |
cardiovascular |
| T323 |
741-752 |
CHEBI:27584;CHEBI:27584 |
denotes |
focused on |
| T190 |
756-766 |
GO:0065007 |
denotes |
regulation |
| T191 |
770-774 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T324 |
772-787 |
UBERON:0001236 |
denotes |
E2 in cardiac m |
| T192 |
778-785 |
UBERON:0000948;CL:0000746 |
denotes |
cardiac |
| T193 |
786-794 |
CL:0000746 |
denotes |
myocytes |
| T194 |
799-806 |
UBERON:0000948;CL:0002548 |
denotes |
cardiac |
| T195 |
807-818 |
CL:0002548 |
denotes |
fibroblasts |
| T325 |
832-840 |
UBERON:0002198 |
denotes |
ated tha |
| T326 |
842-853 |
CHEBI:27584;CHEBI:27584 |
denotes |
although An |
| T196 |
851-857 |
PR:000036009 |
denotes |
Ang II |
| T327 |
864-872 |
GO:0016020 |
denotes |
icantly |
| T328 |
873-877 |
G_3;PG_10;PR:000003622 |
denotes |
educ |
| T329 |
878-888 |
GO:0010467 |
denotes |
d ACE2 act |
| T197 |
880-884 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T330 |
890-900 |
UBERON:0001986;PR:000006897 |
denotes |
ity and do |
| T331 |
900-902 |
PR:000006897 |
denotes |
wn |
| T198 |
912-916 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T332 |
912-925 |
PR:000036013 |
denotes |
ACE2 mRNA in |
| T199 |
925-932 |
UBERON:0000948;CL:0000746 |
denotes |
cardiac |
| T333 |
929-933 |
PR:000036013 |
denotes |
iac |
| T200 |
933-941 |
CL:0000746 |
denotes |
myocytes |
| T334 |
941-954 |
GO:0005576 |
denotes |
, it only red |
| T201 |
959-963 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T335 |
962-971 |
GO:0065007 |
denotes |
2 activit |
| T202 |
976-987 |
CL:0000057 |
denotes |
fibroblasts |
| T336 |
986-990 |
PR:000000103 |
denotes |
s (2 |
| T203 |
997-1005 |
CL:0000187 |
denotes |
myocytes |
| T337 |
1001-1007 |
PR:000036009 |
denotes |
ytes, |
| T204 |
1007-1017 |
UBERON:0001986 |
denotes |
endothelin |
| T205 |
1054-1058 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T338 |
1071-1075 |
PR:000036013 |
denotes |
ion |
| T339 |
1082-1086 |
PR:000003622;G_3;PG_10 |
denotes |
his |
| T206 |
1099-1103 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T207 |
1112-1118 |
PR:000036009 |
denotes |
Ang II |
| T208 |
1122-1126 |
PR:000006897 |
denotes |
ET-1 |
| T209 |
1142-1152 |
CHEBI:35222;CHEBI:35222 |
denotes |
inhibitors |
| T340 |
1155-1160 |
PR:000036013 |
denotes |
mito |
| T210 |
1156-1163 |
CHEBI:52290;CHEBI:52290;PR:000000103 |
denotes |
mitogen |
| T211 |
1163-1190 |
PR:000000103 |
denotes |
-activated protein kinase 1 |
| T212 |
1192-1197 |
PR:000000103 |
denotes |
MAPK1 |
| T341 |
1199-1204 |
PR:000036008 |
denotes |
whic |
| T213 |
1221-1227 |
PR:000036009 |
denotes |
Ang II |
| T342 |
1224-1230 |
PR:000036012 |
denotes |
II an |
| T214 |
1232-1236 |
PR:000006897 |
denotes |
ET-1 |
| T215 |
1246-1259 |
GO:0005576 |
denotes |
extracellular |
| T216 |
1267-1276 |
GO:0065007 |
denotes |
regulated |
| T343 |
1267-1277 |
PR:000001898 |
denotes |
regulated |
| T217 |
1285-1288 |
PR:000007130 |
denotes |
ERK |
| T218 |
1291-1295 |
PR:000000103 |
denotes |
ERK2 |
| T219 |
1306-1310 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T344 |
1312-1317 |
PR:000013883 |
denotes |
29). |
| T9018 |
1338-1343 |
G_3;PG_10;PR:000003622 |
denotes |
murin |
| T220 |
1338-1344 |
NCBITaxon:39107 |
denotes |
murine |
| T63740 |
1344-1354 |
GO:0065007 |
denotes |
studies s |
| T78761 |
1359-1373 |
UBERON:0004535 |
denotes |
Ang II−mediat |
| T221 |
1360-1366 |
PR:000036009 |
denotes |
Ang II |
| T222 |
1384-1392 |
GO:0016020 |
denotes |
membrane |
| T223 |
1399-1412 |
CL:0000746 |
denotes |
cardiomyocyte |
| T224 |
1413-1417 |
PR:000003622;G_3;PG_10 |
denotes |
ACE2 |
| T29306 |
1422-1436 |
UBERON:0004535 |
denotes |
elated with th |
| T37860 |
1450-1460 |
GO:0065007 |
denotes |
of TACE/A |
| T225 |
1459-1465 |
PR:000001279 |
denotes |
ADAM17 |
| T4521 |
1469-1479 |
CHEBI:35222;CHEBI:35222 |
denotes |
ivity, whi |
| T226 |
1501-1504 |
PR:000001251 |
denotes |
AT1 |
| T227 |
1529-1536 |
UBERON:0000948;CL:0002548 |
denotes |
Cardiac |
| T228 |
1537-1548 |
CL:0002548 |
denotes |
fibroblasts |
| T92757 |
1546-1560 |
UBERON:0004535 |
denotes |
ts and coronar |
| T229 |
1553-1561 |
UBERON:0005985;CL:0002364 |
denotes |
coronary |
| T230 |
1562-1573 |
UBERON:0001986;CL:0000115 |
denotes |
endothelial |
| T231 |
1574-1579 |
CL:0000115 |
denotes |
cells |
| T232 |
1585-1592 |
GO:0010467 |
denotes |
express |
| T233 |
1593-1597 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T234 |
1602-1606 |
PR:000001279 |
denotes |
TACE |
| T57057 |
1618-1623 |
PR:000013883 |
denotes |
ecipr |
| T50692 |
1660-1676 |
SP_7 |
denotes |
ll types as well |
| T26520 |
1678-1691 |
PR:000036008 |
denotes |
31,32). Ang I |
| T235 |
1686-1692 |
PR:000036009 |
denotes |
Ang II |
| T11517 |
1693-1698 |
PR:000036008 |
denotes |
activ |
| T49885 |
1716-1722 |
PR:000036009 |
denotes |
signa |
| T236 |
1749-1752 |
PR:000045382 |
denotes |
PKC |
| T237 |
1757-1761 |
PR:000009197 |
denotes |
JAK2 |
| T238 |
1762-1767 |
PR:000002089 |
denotes |
STAT3 |
| T78357 |
1796-1806 |
CHEBI:35222;CHEBI:35222 |
denotes |
sults in m |
| T239 |
1805-1815 |
UBERON:0002349 |
denotes |
myocardial |
| T32486 |
1840-1846 |
PR:000036009 |
denotes |
d fibr |
| T30438 |
1868-1872 |
PR:000001251 |
denotes |
of |
| T240 |
1872-1876 |
PR:000036013 |
denotes |
Ang1 |
| T241 |
1897-1903 |
SO:0000417 |
denotes |
domain |
| T84915 |
1900-1916 |
UBERON:0002053 |
denotes |
ain also inhibit |
| T242 |
1922-1933 |
GO:0006508 |
denotes |
proteolytic |
| T14662 |
1924-1939 |
UBERON:0001236 |
denotes |
oteolytic funct |
| T3622 |
1954-1965 |
CHEBI:27584;CHEBI:27584 |
denotes |
enzyme and |
| T2367 |
1991-2008 |
CHEBI:25354;CHEBI:25354 |
denotes |
on (34). Studies |
| T243 |
2011-2016 |
SP_6;NCBITaxon:9606 |
denotes |
human |
| T70131 |
2030-2035 |
CHEBI:15377;CHEBI:15377 |
denotes |
cardi |
| T244 |
2030-2037 |
UBERON:0000948 |
denotes |
cardiac |
| T245 |
2038-2044 |
UBERON:0000479 |
denotes |
tissue |
| T246 |
2049-2055 |
UBERON:0001969 |
denotes |
plasma |
| T247 |
2063-2067 |
PR:000036013 |
denotes |
Ang1 |
| T22478 |
2065-2069 |
CHEBI:24866;CHEBI:24866 |
denotes |
g1-7 |
| T53819 |
2100-2117 |
CHEBI:25354;CHEBI:25354 |
denotes |
han Ang I, which |
| T248 |
2104-2109 |
PR:000036008 |
denotes |
Ang I |
| T50077 |
2118-2138 |
CHEBI:48561;CHEBI:48561 |
denotes |
uggests the inhibito |
| T249 |
2152-2156 |
PR:000036013 |
denotes |
Ang1 |
| T85097 |
2167-2175 |
UBERON:0002198 |
denotes |
ay contr |
| T97767 |
2177-2183 |
PR:000036009 |
denotes |
ute to |
| T250 |
2230-2234 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T62349 |
2236-2241 |
CHEBI:15377;CHEBI:15377 |
denotes |
nocko |
| T251 |
2244-2248 |
NCBITaxon:10088 |
denotes |
mice |
| T252 |
2254-2260 |
PR:000036009 |
denotes |
Ang II |
| T2176 |
2269-2276 |
UBERON:0000479 |
denotes |
and re |
| T253 |
2286-2290 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T254 |
2311-2315 |
PR:000000104 |
denotes |
ERK1 |
| T255 |
2319-2323 |
PR:000009197 |
denotes |
JAK2 |
| T256 |
2324-2329 |
PR:000002089 |
denotes |
STAT3 |
| T257 |
2335-2338 |
PR:000045382;GO:0000187 |
denotes |
PKC |
| T70273 |
2339-2347 |
MOP:0000568 |
denotes |
signalin |
| T258 |
2339-2348 |
GO:0000165 |
denotes |
signaling |
| T88849 |
2360-2369 |
GO:0006915 |
denotes |
nd was at |
| T259 |
2417-2423 |
PR:000036009 |
denotes |
Ang II |
| T260 |
2432-2442 |
UBERON:0002349 |
denotes |
myocardial |
| T55720 |
2453-2456 |
CHEBI:37886;CHEBI:37886;PR:000036009 |
denotes |
y a |
| T28600 |
2457-2459 |
PR:000036009 |
denotes |
d |
| T83802 |
2471-2475 |
PR:000001251 |
denotes |
imp |
| T53803 |
2477-2483 |
PR:000036009 |
denotes |
vement |
| T72294 |
2509-2522 |
PR:000036013 |
denotes |
(33). Other s |
| T20825 |
2526-2531 |
PR:000036013 |
denotes |
es hi |
| T14954 |
2539-2543 |
PR:000003622;G_3;PG_10 |
denotes |
d th |
| T261 |
2557-2561 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T262 |
2562-2566 |
PR:000036013 |
denotes |
Ang1 |
| T39929 |
2565-2568 |
PR:000001563 |
denotes |
1-7 |
| T263 |
2581-2591 |
GO:0065007 |
denotes |
modulating |
| T264 |
2596-2606 |
GO:0010467 |
denotes |
expression |
| T49406 |
2621-2625 |
G_3;PG_10;PR:000003622 |
denotes |
ator |
| T29031 |
2626-2630 |
PR:000036013 |
denotes |
cyt |
| T265 |
2646-2651 |
PR:000000134 |
denotes |
TNF-α |
| T266 |
2674-2678 |
PR:000001393 |
denotes |
IL-6 |
| T267 |
2680-2688 |
CL:0000576;PR:000002122 |
denotes |
monocyte |
| T268 |
2689-2714 |
PR:000002122 |
denotes |
chemoattractant protein-1 |
| T97645 |
2697-2702 |
PR:000013883 |
denotes |
racta |
| T269 |
2720-2748 |
PR:000000046 |
denotes |
transforming growth factor-β |
| T54224 |
2729-2733 |
PR:000001251 |
denotes |
ing |
| T94906 |
2738-2742 |
PR:000003622;G_3;PG_10 |
denotes |
h fa |
| T270 |
2752-2759 |
UBERON:0000948 |
denotes |
cardiac |
| T80849 |
2756-2762 |
PR:000036009 |
denotes |
iac an |
| T271 |
2767-2771 |
UBERON:0002048 |
denotes |
lung |
| T57333 |
2774-2778 |
PR:000001251 |
denotes |
bros |
| T272 |
2782-2791 |
UBERON:0002048 |
denotes |
pulmonary |
| T66538 |
2802-2806 |
PR:000003622;G_3;PG_10 |
denotes |
on, |
| T53794 |
2864-2868 |
G_3;PG_10;PR:000003622 |
denotes |
). |
| T273 |
2885-2889 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T274 |
2890-2894 |
PR:000036013 |
denotes |
Ang1 |
| T275 |
2897-2900 |
PR:000001563 |
denotes |
Mas |
| T276 |
2906-2932 |
GO:0065007 |
denotes |
Regulation
Angiotensinogen |
| T49835 |
2908-2914 |
PR:000036009 |
denotes |
gulati |
| T23691 |
2929-2934 |
PR:000036013 |
denotes |
gen i |
| T96566 |
2938-2942 |
G_3;PG_10;PR:000003622 |
denotes |
nver |
| T277 |
2949-2962 |
PR:000036008 |
denotes |
angiotensin I |
| T278 |
2964-2969 |
PR:000036008 |
denotes |
Ang I |
| T279 |
2975-2980 |
PR:000013883 |
denotes |
renin |
| T280 |
2982-2987 |
PR:000036008 |
denotes |
Ang I |
| T43762 |
3001-3013 |
SP_10 |
denotes |
to Ang II vi |
| T281 |
3004-3010 |
PR:000036009 |
denotes |
Ang II |
| T84544 |
3014-3024 |
SP_10;UBERON:0001004 |
denotes |
angiotens |
| T62103 |
3025-3045 |
SP_10 |
denotes |
n-converting enzyme |
| T45099 |
3047-3055 |
SP_10 |
denotes |
CE), whi |
| T96697 |
3063-3071 |
SP_10 |
denotes |
hydrolyz |
| T282 |
3063-3073 |
MOP:0000619 |
denotes |
hydrolyzes |
| T67126 |
3073-3077 |
G_3;PG_10;PR:000003622 |
denotes |
bra |
| T283 |
3074-3084 |
CHEBI:3165;CHEBI:3165 |
denotes |
bradykinin |
| T70630 |
3087-3096 |
PG_1 |
denotes |
to its in |
| T284 |
3103-3114 |
CHEBI:25212;CHEBI:25212 |
denotes |
metabolites |
| T4074 |
3122-3127 |
NCBITaxon:10239;GO:0035376 |
denotes |
ing i |
| T7619 |
3128-3133 |
GO:0035376 |
denotes |
flamm |
| T1702 |
3143-3155 |
GO:0044164 |
denotes |
pro-inflamm |
| T285 |
3172-3178 |
PR:000036009 |
denotes |
Ang II |
| T51851 |
3186-3191 |
NCBITaxon:10239;GO:0006260 |
denotes |
iated |
| T38954 |
3192-3203 |
GO:0006260 |
denotes |
by Ang II t |
| T286 |
3195-3201 |
PR:000036009 |
denotes |
Ang II |
| T34720 |
3218-3224 |
PR:000036009 |
denotes |
(AT1), |
| T28581 |
3233-3238 |
PR:000003622;G_3;PG_10 |
denotes |
imula |
| T287 |
3242-3253 |
CHEBI:27584;CHEBI:27584 |
denotes |
aldosterone |
| T52593 |
3267-3272 |
NCBITaxon:10239 |
denotes |
m the |
| T288 |
3273-3288 |
UBERON:0001236 |
denotes |
adrenal medulla |
| T289 |
3333-3342 |
UBERON:0002198 |
denotes |
pituitary |
| T53738 |
3338-3342 |
PR:000001251 |
denotes |
tary |
| T290 |
3344-3355 |
CHEBI:27584;CHEBI:27584 |
denotes |
Aldosterone |
| T291 |
3366-3374 |
GO:0016020 |
denotes |
membrane |
| T14088 |
3367-3372 |
PR:000001607 |
denotes |
embra |
| T292 |
3375-3379 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T293 |
3380-3390 |
GO:0010467 |
denotes |
expression |
| T294 |
3392-3402 |
UBERON:0001986;PR:000006897 |
denotes |
Endothelin |
| T295 |
3402-3404 |
PR:000006897 |
denotes |
-1 |
| T296 |
3414-3427 |
PR:000036013 |
denotes |
angiotensin 1 |
| T411 |
3423-3428 |
PR:000013883 |
denotes |
in 1- |
| T297 |
3431-3435 |
PR:000036013 |
denotes |
Ang1 |
| T298 |
3443-3456 |
GO:0005576 |
denotes |
extracellular |
| T299 |
3464-3473 |
GO:0065007 |
denotes |
regulated |
| T412 |
3465-3473 |
SP_7 |
denotes |
egulated |
| T413 |
3484-3497 |
PR:000036008 |
denotes |
K)1/ERK2 path |
| T300 |
3488-3492 |
PR:000000103 |
denotes |
ERK2 |
| T414 |
3499-3504 |
PR:000036008 |
denotes |
ys. A |
| T301 |
3503-3509 |
PR:000036009 |
denotes |
Ang II |
| T302 |
3573-3577 |
PR:000036013 |
denotes |
Ang1 |
| T303 |
3584-3588 |
PR:000003622;G_3;PG_10 |
denotes |
ACE2 |
| T415 |
3646-3652 |
PR:000036009 |
denotes |
recep |
| T304 |
3657-3662 |
PR:000036013 |
denotes |
Ang1- |
| T416 |
3674-3678 |
PR:000001251 |
denotes |
e fo |
| T305 |
3701-3706 |
PR:000036008 |
denotes |
Ang I |
| T417 |
3706-3722 |
UBERON:0002053 |
denotes |
to an intermedi |
| T306 |
3726-3732 |
PR:000036012 |
denotes |
Ang1-9 |
| T418 |
3730-3745 |
UBERON:0001236 |
denotes |
-9 or directly |
| T419 |
3762-3773 |
CHEBI:27584;CHEBI:27584 |
denotes |
eptidase ne |
| T307 |
3771-3781 |
PR:000001898 |
denotes |
neprilysin |
| T420 |
3799-3816 |
CHEBI:25354;CHEBI:25354 |
denotes |
ase (PEP). RAS = |
| T308 |
3816-3821 |
PR:000013883 |
denotes |
renin |
