| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-77 |
DRI_Background |
denotes |
Prominent changes in blood coagulation of patients with SARS-CoV-2 infection. |
| T2 |
78-276 |
DRI_Outcome |
denotes |
Background As the number of patients increases, there is a growing understanding of the form of pneumonia sustained by the 2019 novel coronavirus (SARS-CoV-2), which has caused an outbreak in China. |
| T3 |
277-386 |
DRI_Background |
denotes |
Up to now, clinical features and treatment of patients infected with SARS-CoV-2 have been reported in detail. |
| T4 |
387-476 |
DRI_Background |
denotes |
However, the relationship between SARS-CoV-2 and coagulation has been scarcely addressed. |
| T5 |
477-572 |
DRI_Approach |
denotes |
Our aim is to investigate the blood coagulation function of patients with SARS-CoV-2 infection. |
| T6 |
573-696 |
DRI_Approach |
denotes |
Methods In our study, 94 patients with confirmed SARS-CoV-2 infection were admitted in Renmin Hospital of Wuhan University. |
| T7 |
697-813 |
DRI_Approach |
denotes |
We prospectively collect blood coagulation data in these patients and in 40 healthy controls during the same period. |
| T8 |
909-1080 |
DRI_Outcome |
denotes |
The values of D-dimer, fibrin/fibrinogen degradation products (FDP), and fibrinogen (FIB) in all SARS-CoV-2 cases were substantially higher than those in healthy controls. |
| T9 |
1081-1212 |
DRI_Outcome |
denotes |
Moreover, D-dimer and FDP values in patients with severe SARS-CoV-2 infection were higher than those in patients with milder forms. |
| T10 |
1314-1399 |
DRI_Approach |
denotes |
Thrombin time in critical SARS-CoV-2 patients was also shorter than that in controls. |
| T11 |
1400-1619 |
DRI_Challenge |
denotes |
Conclusions The coagulation function in patients with SARS-CoV-2 is significantly deranged compared with healthy people, but monitoring D-dimer and FDP values may be helpful for the early identification of severe cases. |
