LitCovid-ArguminSci  

PubMed:32105632 JSONTXT 16 Projects

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Id Subject Object Predicate Lexical cue
T1 0-153 DRI_Background denotes Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.
T2 154-314 DRI_Challenge denotes BACKGROUND: An ongoing outbreak of pneumonia associated with the severe acute respiratory coronavirus 2 (SARS-CoV-2) started in December, 2019, in Wuhan, China.
T3 315-393 DRI_Challenge denotes Information about critically ill patients with SARS-CoV-2 infection is scarce.
T4 394-501 DRI_Challenge denotes We aimed to describe the clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia.
T5 502-785 DRI_Background denotes METHODS: In this single-centered, retrospective, observational study, we enrolled 52 critically ill adult patients with SARS-CoV-2 pneumonia who were admitted to the intensive care unit (ICU) of Wuhan Jin Yin-tan hospital (Wuhan, China) between late December, 2019, and Jan 26, 2020.
T6 786-901 DRI_Background denotes Demographic data, symptoms, laboratory values, comorbidities, treatments, and clinical outcomes were all collected.
T7 902-957 DRI_Background denotes Data were compared between survivors and non-survivors.
T8 958-1018 DRI_Approach denotes The primary outcome was 28-day mortality, as of Feb 9, 2020.
T9 1019-1186 DRI_Background denotes Secondary outcomes included incidence of SARS-CoV-2-related acute respiratory distress syndrome (ARDS) and the proportion of patients requiring mechanical ventilation.
T10 1187-1287 DRI_Background denotes FINDINGS: Of 710 patients with SARS-CoV-2 pneumonia, 52 critically ill adult patients were included.
T11 1288-1414 DRI_Outcome denotes The mean age of the 52 patients was 59·7 (SD 13·3) years, 35 (67%) were men, 21 (40%) had chronic illness, 51 (98%) had fever.
T12 1415-1577 DRI_Outcome denotes 32 (61·5%) patients had died at 28 days, and the median duration from admission to the intensive care unit (ICU) to death was 7 (IQR 3-11) days for non-survivors.
T13 1578-1866 DRI_Outcome denotes Compared with survivors, non-survivors were older (64·6 years [11·2] vs 51·9 years [12·9]), more likely to develop ARDS (26 [81%] patients vs 9 [45%] patients), and more likely to receive mechanical ventilation (30 [94%] patients vs 7 [35%] patients), either invasively or non-invasively.
T14 1867-2067 DRI_Outcome denotes Most patients had organ function damage, including 35 (67%) with ARDS, 15 (29%) with acute kidney injury, 12 (23%) with cardiac injury, 15 (29%) with liver dysfunction, and one (2%) with pneumothorax.
T15 2068-2118 DRI_Background denotes 37 (71%) patients required mechanical ventilation.
T16 2119-2182 DRI_Background denotes Hospital-acquired infection occurred in seven (13·5%) patients.
T17 2183-2282 DRI_Challenge denotes INTERPRETATION: The mortality of critically ill patients with SARS-CoV-2 pneumonia is considerable.
T18 2283-2375 DRI_Outcome denotes The survival time of the non-survivors is likely to be within 1-2 weeks after ICU admission.
T19 2376-2462 DRI_Background denotes Older patients (>65 years) with comorbidities and ARDS are at increased risk of death.
T20 2463-2619 DRI_Challenge denotes The severity of SARS-CoV-2 pneumonia poses great strain on critical care resources in hospitals, especially if they are not adequately staffed or resourced.