LitCovid-ArguminSci  

PubMed:32096367 JSONTXT 37 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 77-168 DRI_Challenge denotes The current epidemic situation of corona virus disease-19 (COVID-19) still remained severe.
T2 169-345 DRI_Approach denotes As the National Clinical Research Center for Infectious Diseases, the First Affiliated Hospital of Zhejiang University School of Medicine is the primary medical care center for
T3 366-375 DRI_Approach denotes Province.
T4 648-849 DRI_Approach denotes The "Four-Anti and Two-Balance"strategy included antivirus, anti-shock, anti-hyoxemia, anti-secondary infection, and maintaining of water, electrolyte and acid base balance and microecological balance.
T5 850-958 DRI_Background denotes Meanwhile, integrated multidisciplinarypersonalized treatment was recommended to improve therapeutic effect.
T6 959-1113 DRI_Background denotes The importance of early viralogical detection, dynamic monitoring of inflammatory indexes and chest radiograph was emphasized in clinical decision-making.
T7 1184-1329 DRI_Background denotes Viral nucleic acids could be detected in10% patients'blood samples at acute periodand 50% of patients had positive RT-PCR results in their feces.
T8 1330-1564 DRI_Outcome denotes We also isolated alive viral strains from feces, indicating potential infectiousness of feces.Dynamic cytokine detection was necessary to timely identifyingcytokine storms and application of artificial liver blood purification system.
T9 1565-1658 DRI_Approach denotes The "Four-Anti and Two-Balance"strategyeffectively increased cure rate and reduced mortality.
T10 1659-1841 DRI_Outcome denotes Early antiviral treatment could alleviate disease severity and prevent illness progression, and we found lopinavir/ritonavir combined with abidol showed antiviraleffects in COVID-19.
T11 1842-1901 DRI_Background denotes Shock and hypoxemia were usually caused by cytokine storms.
T12 1902-2148 DRI_Background denotes The artificial liver blood purification system could rapidly remove inflammatory mediators and block cytokine storm.Moreover, it also favoredthe balance of fluid, electrolyte and acid-base and thus improved treatment efficacy in critical illness.
T13 2149-2248 DRI_Background denotes For cases of severe illness, early and also short periods of moderate glucocorticoid was supported.
T14 2249-2346 DRI_Approach denotes Patients with oxygenation index below 200 mmHg should be transferred to intensive medical center.
T15 2347-2437 DRI_Background denotes Conservative oxygen therapy was preferred and noninvasive ventilation was not recommended.
T16 2438-2572 DRI_Background denotes Patients with mechanical ventilation should be strictly supervised with cluster ventilator-associated pneumonia prevention strategies.
T17 2573-2942 DRI_Background denotes Antimicrobial prophylaxis should be prescribed rationally and was not recommended except for patients with long course of disease, repeated fever and elevated procalcitonin (PCT), meanwhile secondary fungal infection should be concerned.Some patients with COVID-19 showed intestinal microbialdysbiosis with decreasedprobiotics such as Lactobacillus and Bifidobacterium.
T18 2943-3223 DRI_Background denotes Nutritional and gastrointestinal function should be assessed for all patients.Nutritional support and application of prebiotics or probiotics were suggested to regulate the balance of intestinal microbiota and reduce the risk of secondary infection due to bacterial translocation.
T19 3224-3279 DRI_Background denotes Anxiety and fear were common in patients with COVID-19.
T20 3280-3362 DRI_Approach denotes Therefore, we established dynamic assessment and warning for psychological crisis.
T21 3363-3509 DRI_Background denotes We also integrated Chinese medicine in treatment to promote disease rehabilitation through classification methods of traditional Chinese medicine.
T22 3510-3591 DRI_Approach denotes We optimized nursing process for severe patients to promote their rehabilitation.
T23 3592-3673 DRI_Background denotes It remained unclear about viral clearance pattern after the SARS-CoV-2 infection.
T24 3674-3895 DRI_Approach denotes Therefore, two weeks' quarantine for discharged patients was required and a regular following up was also needed.The Zhejiang experience above and suggestions have been implemented in our center and achieved good results.
T25 3896-4048 DRI_Background denotes However, since COVID-19 was a newly emerging disease, more work was warranted to improve strategies of prevention, diagnosis and treatment for COVID-19.