| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-82 |
DRI_Background |
denotes |
Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China. |
| T2 |
83-235 |
DRI_Background |
denotes |
BACKGROUND: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been widely spread. |
| T3 |
236-342 |
DRI_Approach |
denotes |
We aim to investigate the clinical characteristic and allergy status of patients infected with SARS-CoV-2. |
| T4 |
343-606 |
DRI_Background |
denotes |
METHODS: Electronic medical records including demographics, clinical manifestation, comorbidities, laboratory data, and radiological materials of 140 hospitalized COVID-19 patients, with confirmed result of SARS-CoV-2 viral infection, were extracted and analyzed. |
| T5 |
607-740 |
DRI_Outcome |
denotes |
RESULTS: An approximately 1:1 ratio of male (50.7%) and female COVID-19 patients was found, with an overall median age of 57.0 years. |
| T6 |
741-784 |
DRI_Approach |
denotes |
All patients were community-acquired cases. |
| T7 |
785-1010 |
DRI_Background |
denotes |
Fever (91.7%), cough (75.0%), fatigue (75.0%), and gastrointestinal symptoms (39.6%) were the most common clinical manifestations, whereas hypertension (30.0%) and diabetes mellitus (12.1%) were the most common comorbidities. |
| T8 |
1011-1101 |
DRI_Background |
denotes |
Drug hypersensitivity (11.4%) and urticaria (1.4%) were self-reported by several patients. |
| T9 |
1102-1177 |
DRI_Background |
denotes |
Asthma or other allergic diseases were not reported by any of the patients. |
| T10 |
1178-1275 |
DRI_Background |
denotes |
Chronic obstructive pulmonary disease (COPD, 1.4%) patients and current smokers (1.4%) were rare. |
| T11 |
1375-1450 |
DRI_Background |
denotes |
Lymphopenia (75.4%) and eosinopenia (52.9%) were observed in most patients. |
| T12 |
1451-1619 |
DRI_Approach |
denotes |
Blood eosinophil counts correlate positively with lymphocyte counts in severe (r = .486, P < .001) and nonsevere (r = .469, P < .001) patients after hospital admission. |
| T13 |
1620-1781 |
DRI_Background |
denotes |
Significantly higher levels of D-dimer, C-reactive protein, and procalcitonin were associated with severe patients compared to nonsevere patients (all P < .001). |
| T14 |
1782-1951 |
DRI_Challenge |
denotes |
CONCLUSION: Detailed clinical investigation of 140 hospitalized COVID-19 cases suggests eosinopenia together with lymphopenia may be a potential indicator for diagnosis. |
| T15 |
1952-2034 |
DRI_Challenge |
denotes |
Allergic diseases, asthma, and COPD are not risk factors for SARS-CoV-2 infection. |
| T16 |
2035-2157 |
DRI_Background |
denotes |
Older age, high number of comorbidities, and more prominent laboratory abnormalities were associated with severe patients. |
