LitCovid-ArguminSci  

PubMed:31986264 JSONTXT 21 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 0-83 DRI_Background denotes Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.
T2 84-227 DRI_Background denotes BACKGROUND: A recent cluster of pneumonia cases in Wuhan, China, was caused by a novel betacoronavirus, the 2019 novel coronavirus (2019-nCoV).
T3 228-368 DRI_Outcome denotes We report the epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of these patients.
T4 369-464 DRI_Background denotes METHODS: All patients with suspected 2019-nCoV were admitted to a designated hospital in Wuhan.
T5 465-526 DRI_Outcome denotes We prospectively collected and analysed data on patients with
T6 558-619 DRI_Outcome denotes infection by real-time RT-PCR and next-generation sequencing.
T7 620-806 DRI_Approach denotes Data were obtained with standardised data collection forms shared by WHO and the International Severe Acute Respiratory and Emerging Infection Consortium from electronic medical records.
T8 807-924 DRI_Background denotes Researchers also directly communicated with patients or their families to ascertain epidemiological and symptom data.
T9 925-1047 DRI_Background denotes Outcomes were also compared between patients who had been admitted to the intensive care unit (ICU) and those who had not.
T10 1048-1133 DRI_Background denotes FINDINGS: By Jan 2, 2020, 41 admitted hospital patients had been identified as having
T11 1165-1175 DRI_Background denotes infection.
T12 1176-1383 DRI_Outcome denotes Most of the infected patients were men (30 [73%] of 41); less than half had underlying diseases (13 [32%]), including diabetes (eight [20%]), hypertension (six [15%]), and cardiovascular disease (six [15%]).
T13 1427-1493 DRI_Background denotes 27 (66%) of 41 patients had been exposed to Huanan seafood market.
T14 1524-1803 DRI_Outcome denotes Common symptoms at onset of illness were fever (40 [98%] of 41 patients), cough (31 [76%]), and myalgia or fatigue (18 [44%]); less common symptoms were sputum production (11 [28%] of 39), headache (three [8%] of 38), haemoptysis (two [5%] of 39), and diarrhoea (one [3%] of 38).
T15 1804-1904 DRI_Background denotes Dyspnoea developed in 22 (55%) of 40 patients (median time from illness onset to dyspnoea 8·0 days [
T16 1916-1919 DRI_Background denotes ]).
T17 2027-2191 DRI_Background denotes Complications included acute respiratory distress syndrome (12 [29%]), RNAaemia (six [15%]), acute cardiac injury (five [12%]) and secondary infection (four [10%]).
T18 2192-2253 DRI_Background denotes 13 (32%) patients were admitted to an ICU and six (15%) died.
T19 2254-2377 DRI_Background denotes Compared with non-ICU patients, ICU patients had higher plasma levels of IL2, IL7, IL10, GSCF, IP10, MCP1, MIP1A, and TNFα.
T20 2378-2578 DRI_Challenge denotes INTERPRETATION: The 2019-nCoV infection caused clusters of severe respiratory illness similar to severe acute respiratory syndrome coronavirus and was associated with ICU admission and high mortality.
T21 2579-2735 DRI_Challenge denotes Major gaps in our knowledge of the origin, epidemiology, duration of human transmission, and clinical spectrum of disease need fulfilment by future studies.