LitCoin-sentences  

PubMed:27090298 JSONTXT 35 Projects

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Id Subject Object Predicate Lexical cue
T1 0-50 Sentence denotes Circulating Fatty Acid Synthase in pregnant women:
T2 51-126 Sentence denotes Relationship to blood pressure, maternal metabolism and newborn parameters.
T3 127-232 Sentence denotes The enzyme FASN (fatty acid synthase) is potentially related with hypertension and metabolic dysfunction.
T4 233-280 Sentence denotes FASN is highly expressed in the human placenta.
T5 281-433 Sentence denotes We aimed to investigate the relationship circulating FASN has with blood pressure, maternal metabolism and newborn parameters in healthy pregnant women.
T6 434-705 Sentence denotes Circulating FASN was assessed in 115 asymptomatic pregnant women in the second trimester of gestation along with C-peptide, fasting glucose and insulin, post-load glucose lipids, HMW-adiponectin and blood pressure (the latter was assessed in each trimester of gestation).
T7 706-752 Sentence denotes At birth, newborns and placentas were weighed.
T8 753-814 Sentence denotes FASN expression was also able to be assessed in 80 placentas.
T9 815-1095 Sentence denotes Higher circulating FASN was associated with lower systolic blood pressure (SBP), with a more favourable metabolic phenotype (lower fasting glucose and insulin, post load glucose, HbAc1, HOMA-IR and C-peptide), and with lower placental and birth weight (all p < 0.05 to p < 0.001).
T10 1096-1219 Sentence denotes Placental FASN expression related positively to circulating FASN (p < 0.005) and negatively to placental weight (p < 0.05).
T11 1220-1303 Sentence denotes Our observations suggest a physiological role of placental FASN in human pregnancy.
T12 1304-1533 Sentence denotes Future studies will clarify whether circulating FASN of placental origin does actually regulate placental and fetal growth, and (thereby) has a favourable influence on the pregnant mother's insulin sensitivity and blood pressure.