Id |
Subject |
Object |
Predicate |
Lexical cue |
T1 |
0-56 |
Sentence |
denotes |
MOL1 is required for cambium homeostasis in Arabidopsis. |
T2 |
57-167 |
Sentence |
denotes |
Plants maintain pools of pluripotent stem cells which allow them to constantly produce new tissues and organs. |
T3 |
168-352 |
Sentence |
denotes |
Stem cell homeostasis in shoot and root tips depends on negative regulation by ligand-receptor pairs of the CLE peptide and leucine-rich repeat receptor-like kinase (LRR-RLK) families. |
T4 |
353-482 |
Sentence |
denotes |
However, regulation of the cambium, the stem cell niche required for lateral growth of shoots and roots, is poorly characterized. |
T5 |
483-579 |
Sentence |
denotes |
Here we show that the LRR-RLK MOL1 is necessary for cambium homeostasis in Arabidopsis thaliana. |
T6 |
580-745 |
Sentence |
denotes |
By employing promoter reporter lines, we reveal that MOL1 is active in a domain that is distinct from the domain of the positively acting CLE41/PXY signaling module. |
T7 |
746-933 |
Sentence |
denotes |
In particular, we show that MOL1 acts in an opposing manner to the CLE41/PXY module and that changing the domain or level of MOL1 expression both result in disturbed cambium organization. |
T8 |
934-1074 |
Sentence |
denotes |
Underlining discrete roles of MOL1 and PXY, both LRR-RLKs are not able to replace each other when their expression domains are interchanged. |
T9 |
1075-1168 |
Sentence |
denotes |
Furthermore, MOL1 but not PXY is able to rescue CLV1 deficiency in the shoot apical meristem. |
T10 |
1169-1425 |
Sentence |
denotes |
By identifying genes mis-expressed in mol1 mutants, we demonstrate that MOL1 represses genes associated with stress-related ethylene and jasmonic acid hormone signaling pathways which have known roles in coordinating lateral growth of the Arabidopsis stem. |
T11 |
1426-1712 |
Sentence |
denotes |
Our findings provide evidence that common regulatory mechanisms in different plant stem cell niches are adapted to specific niche anatomies and emphasize the importance of a complex spatial organization of intercellular signaling cascades for a strictly bidirectional tissue production. |