PubMed:24671324 JSONTXT 28 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 0-132 Sentence denotes Necrotising fasciitis after bortezomib and dexamethasone-containing regimen in an elderly patient of Waldenström macroglobulinaemia.
T2 133-307 Sentence denotes Bortezomib and high-dose dexamethasone-containing regimens are considered to be generally tolerable with few severe bacterial infections in patients with B-cell malignancies.
T3 308-397 Sentence denotes However, information is limited concerning the safety of the regimen in elderly patients.
T4 398-614 Sentence denotes We report a case of a 76-year-old man with Waldenström macroglobulinaemia who suffered necrotising fasciitis without neutropenia after the combination treatment with bortezomib, high-dose dexamethasone and rituximab.
T5 615-702 Sentence denotes Despite immediate intravenous antimicrobial therapy, he succumbed 23 h after the onset.
T6 703-905 Sentence denotes Physicians should recognise the possibility of fatal bacterial infections related to bortezomib plus high-dose dexamethasone in elderly patients, and we believe this case warrants further investigation.