LitCoin-sentences  

PubMed:23952588 JSONTXT 25 Projects

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Id Subject Object Predicate Lexical cue
T1 0-113 Sentence denotes Risk factors and predictors of levodopa-induced dyskinesia among multiethnic Malaysians with Parkinson's disease.
T2 114-125 Sentence denotes UNLABELLED:
T3 126-252 Sentence denotes Chronic pulsatile levodopa therapy for Parkinson's disease (PD) leads to the development of motor fluctuations and dyskinesia.
T4 253-370 Sentence denotes We studied the prevalence and predictors of levodopa-induced dyskinesia among multiethnic Malaysian patients with PD.
T5 371-379 Sentence denotes METHODS:
T6 380-498 Sentence denotes This is a cross-sectional study involving 95 patients with PD on uninterrupted levodopa therapy for at least 6 months.
T7 499-548 Sentence denotes The instrument used was the UPDRS questionnaires.
T8 549-642 Sentence denotes The predictors of dyskinesia were determined using multivariate logistic regression analysis.
T9 643-651 Sentence denotes RESULTS:
T10 652-686 Sentence denotes The mean age was 65.6 ± 8.5 years.
T11 687-727 Sentence denotes The mean onset age was 58.5 ± 9.8 years.
T12 728-772 Sentence denotes The median disease duration was 6 (7) years.
T13 773-852 Sentence denotes Dyskinesia was present in 44% (n = 42) with median levodopa therapy of 3 years.
T14 853-932 Sentence denotes There were 64.3% Chinese, 31% Malays, and 3.7% Indians and other ethnic groups.
T15 933-1006 Sentence denotes Eighty-one percent of patients with dyskinesia had clinical fluctuations.
T16 1007-1277 Sentence denotes Patients with dyskinesia had lower onset age ( p < 0.001), longer duration of levodopa therapy ( p < 0.001), longer disease duration ( p < 0.001), higher total daily levodopa dose ( p < 0.001), and higher total UPDRS scores ( p = 0.005) than patients without dyskinesia.
T17 1278-1401 Sentence denotes The three significant predictors of dyskinesia were duration of levodopa therapy, onset age, and total daily levodopa dose.
T18 1402-1414 Sentence denotes CONCLUSIONS:
T19 1415-1485 Sentence denotes The prevalence of levodopa-induced dyskinesia in our patients was 44%.
T20 1486-1594 Sentence denotes The most significant predictors were duration of levodopa therapy, total daily levodopa dose, and onset age.