LitCoin-sentences  

PubMed:20722491 JSONTXT 25 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-33 Sentence denotes Safety of capecitabine: a review.
T2 34-58 Sentence denotes IMPORTANCE OF THE FIELD:
T3 59-248 Sentence denotes Fluoropyrimidines, in particular 5-fluorouracil (5-FU), have been the mainstay of treatment for several solid tumors, including colorectal, breast and head and neck cancers, for > 40 years.
T4 249-278 Sentence denotes AREAS COVERED IN THIS REVIEW:
T5 279-384 Sentence denotes This article reviews the pharmacology and efficacy of capecitabine with a special emphasis on its safety.
T6 385-411 Sentence denotes WHAT THE READER WILL GAIN:
T7 412-564 Sentence denotes The reader will gain better insight into the safety of capecitabine in special populations such as patients with advanced age, renal and kidney disease.
T8 565-643 Sentence denotes We also explore different dosing and schedules of capecitabine administration.
T9 644-662 Sentence denotes TAKE HOME MESSAGE:
T10 663-819 Sentence denotes Capecitabine is an oral prodrug of 5-FU and was developed to fulfill the need for a more convenient therapy and provide an improved safety/efficacy profile.
T11 820-999 Sentence denotes It has shown promising results alone or in combination with other chemotherapeutic agents in colorectal, breast, pancreaticobiliary, gastric, renal cell and head and neck cancers.
T12 1000-1123 Sentence denotes The most commonly reported toxic effects of capecitabine are diarrhea, nausea, vomiting, stomatitis and hand-foot syndrome.
T13 1124-1261 Sentence denotes Capecitabine has a well-established safety profile and can be given safely to patients with advanced age, hepatic and renal dysfunctions.