| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-116 |
Sentence |
denotes |
Lack of association between ADRA2B-4825 gene insertion/deletion polymorphism and migraine in Chinese Han population. |
| T2 |
117-127 |
Sentence |
denotes |
OBJECTIVE: |
| T3 |
128-343 |
Sentence |
denotes |
The present study aimed to estimate the association between susceptibility to migraine and the 12-nucleotide insertion/deletion (indel) polymorphism in promoter region of alpha(2B)-adrenergic receptor gene (ADRA2B). |
| T4 |
344-352 |
Sentence |
denotes |
METHODS: |
| T5 |
353-466 |
Sentence |
denotes |
A case-control study was carried out in Chinese Han population, including 368 cases of migraine and 517 controls. |
| T6 |
467-589 |
Sentence |
denotes |
Genomic DNA was extracted from blood samples, and DNA fragments containing the site of polymorphism were amplified by PCR. |
| T7 |
590-707 |
Sentence |
denotes |
Data were adjusted for sex, age, migraine history and family history, and analyzed using a logistic regression model. |
| T8 |
708-716 |
Sentence |
denotes |
RESULTS: |
| T9 |
717-826 |
Sentence |
denotes |
There was no association between indel polymorphism and migraine, at either the allele or the genotype level. |
| T10 |
827-838 |
Sentence |
denotes |
CONCLUSION: |
| T11 |
839-1046 |
Sentence |
denotes |
These findings do not support a functional significance of ADRA2B indel polymorphism at position -4825 relative to the start codon in the far upstream region of the promoter in the present migraine subjects. |
