LitCoin-sentences  

PubMed:19957053 JSONTXT 24 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-106 Sentence denotes Phenylephrine but not ephedrine reduces frontal lobe oxygenation following anesthesia-induced hypotension.
T2 107-118 Sentence denotes BACKGROUND:
T3 119-189 Sentence denotes Vasopressor agents are used to correct anesthesia-induced hypotension.
T4 190-324 Sentence denotes We describe the effect of phenylephrine and ephedrine on frontal lobe oxygenation (S(c)O(2)) following anesthesia-induced hypotension.
T5 325-333 Sentence denotes METHODS:
T6 334-560 Sentence denotes Following induction of anesthesia by fentanyl (0.15 mg kg(-1)) and propofol (2.0 mg kg(-1)), 13 patients received phenylephrine (0.1 mg iv) and 12 patients received ephedrine (10 mg iv) to restore mean arterial pressure (MAP).
T7 561-680 Sentence denotes Heart rate (HR), MAP, stroke volume (SV), cardiac output (CO), and frontal lobe oxygenation (S(c)O(2)) were registered.
T8 681-689 Sentence denotes RESULTS:
T9 690-806 Sentence denotes Induction of anesthesia was followed by a decrease in MAP, HR, SV, and CO concomitant with an elevation in S(c)O(2).
T10 807-914 Sentence denotes After administration of phenylephrine, MAP increased (51 +/- 12 to 81 +/- 13 mmHg; P < 0.001; mean +/- SD).
T11 915-1062 Sentence denotes However, a 14% (from 70 +/- 8% to 60 +/- 7%) reduction in S(c)O(2) (P < 0.05) followed with no change in CO (3.7 +/- 1.1 to 3.4 +/- 0.9 l min(-1)).
T12 1063-1243 Sentence denotes The administration of ephedrine led to a similar increase in MAP (53 +/- 9 to 79 +/- 8 mmHg; P < 0.001), restored CO (3.2 +/- 1.2 to 5.0 +/- 1.3 l min(-1)), and preserved S(c)O(2).
T13 1244-1256 Sentence denotes CONCLUSIONS:
T14 1257-1461 Sentence denotes The utilization of phenylephrine to correct hypotension induced by anesthesia has a negative impact on S(c)O(2) while ephedrine maintains frontal lobe oxygenation potentially related to an increase in CO.