PubMed:19445921 JSONTXT 23 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 0-101 Sentence denotes Cardioprotective effect of salvianolic acid A on isoproterenol-induced myocardial infarction in rats.
T2 102-253 Sentence denotes The present study was designed to evaluate the cardioprotective potential of salvianolic acid A on isoproterenol-induced myocardial infarction in rats.
T3 254-349 Sentence denotes Hemodynamic parameters and lead II electrocardiograph were monitored and recorded continuously.
T4 350-443 Sentence denotes Cardiac marker enzymes and antioxidative parameters in serum and heart tissues were measured.
T5 444-555 Sentence denotes Assay for mitochondrial respiratory function and histopathological examination of heart tissues were performed.
T6 556-836 Sentence denotes Isoproterenol-treated rats showed significant increases in the levels of lactate dehydrogenase, aspartate transaminase, creatine kinase and malondialdehyde and significant decreases in the activities of superoxide dismutase, catalase and glutathione peroxidase in serum and heart.
T7 837-1045 Sentence denotes These rats also showed declines in left ventricular systolic pressure, maximum and minimum rate of developed left ventricular pressure, and elevation of left ventricular end-diastolic pressure and ST-segment.
T8 1046-1203 Sentence denotes In addition, mitochondrial respiratory dysfunction characterized by decreased respiratory control ratio and ADP/O was observed in isoproterenol-treated rats.
T9 1204-1401 Sentence denotes Administration of salvianolic acid A for a period of 8 days significantly attenuated isoproterenol-induced cardiac dysfunction and myocardial injury and improved mitochondrial respiratory function.
T10 1402-1547 Sentence denotes The protective role of salvianolic acid A against isoproterenol-induced myocardial damage was further confirmed by histopathological examination.
T11 1548-1725 Sentence denotes The results of our study suggest that salvianolic acid A possessing antioxidant activity has a significant protective effect against isoproterenol-induced myocardial infarction.