PubMed:18674790 / 0-563 JSONTXT 19 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 0-88 Sentence denotes High fat diet-fed obese rats are highly sensitive to doxorubicin-induced cardiotoxicity.
T2 89-222 Sentence denotes Often, chemotherapy by doxorubicin (Adriamycin) is limited due to life threatening cardiotoxicity in patients during and posttherapy.
T3 223-341 Sentence denotes Recently, we have shown that moderate diet restriction remarkably protects against doxorubicin-induced cardiotoxicity.
T4 342-528 Sentence denotes This cardioprotection is accompanied by decreased cardiac oxidative stress and triglycerides and increased cardiac fatty-acid oxidation, ATP synthesis, and upregulated JAK/STAT3 pathway.