Id |
Subject |
Object |
Predicate |
Lexical cue |
T1 |
0-88 |
Sentence |
denotes |
High fat diet-fed obese rats are highly sensitive to doxorubicin-induced cardiotoxicity. |
T2 |
89-222 |
Sentence |
denotes |
Often, chemotherapy by doxorubicin (Adriamycin) is limited due to life threatening cardiotoxicity in patients during and posttherapy. |
T3 |
223-341 |
Sentence |
denotes |
Recently, we have shown that moderate diet restriction remarkably protects against doxorubicin-induced cardiotoxicity. |
T4 |
342-528 |
Sentence |
denotes |
This cardioprotection is accompanied by decreased cardiac oxidative stress and triglycerides and increased cardiac fatty-acid oxidation, ATP synthesis, and upregulated JAK/STAT3 pathway. |