LitCoin-sentences  

PubMed:18544179 JSONTXT 23 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-106 Sentence denotes Omitting fentanyl reduces nausea and vomiting, without increasing pain, after sevoflurane for day surgery.
T2 107-132 Sentence denotes BACKGROUND AND OBJECTIVE:
T3 133-266 Sentence denotes Despite advantages of induction and maintenance of anaesthesia with sevoflurane, postoperative nausea and vomiting occurs frequently.
T4 267-374 Sentence denotes Fentanyl is a commonly used supplement that may contribute to this, although it may also improve analgesia.
T5 375-383 Sentence denotes METHODS:
T6 384-572 Sentence denotes This double-blind study examined the incidence and severity of postoperative nausea and vomiting and pain in the first 24 h after sevoflurane anaesthesia in 216 adult day surgery patients.
T7 573-720 Sentence denotes Patients were randomly allocated to either receive or not receive 1 1 fentanyl, while a third group received dexamethasone in addition to fentanyl.
T8 721-729 Sentence denotes RESULTS:
T9 730-1010 Sentence denotes Omission of fentanyl did not reduce the overall incidence of postoperative nausea and vomiting, but did reduce the incidence of vomiting and/or moderate to severe nausea prior to discharge from 20% and 17% with fentanyl and fentanyl-dexamethasone, respectively, to 5% (P = 0.013).
T10 1011-1084 Sentence denotes Antiemetic requirements were reduced from 24% and 31% to 7% (P = 0.0012).
T11 1085-1191 Sentence denotes Dexamethasone had no significant effect on the incidence or severity of postoperative nausea and vomiting.
T12 1192-1514 Sentence denotes Combining the two fentanyl groups revealed further significant benefits from the avoidance of opioids, reducing postoperative nausea and vomiting and nausea prior to discharge from 35% and 33% to 22% and 19% (P = 0.049 and P = 0.035), respectively, while nausea in the first 24 h was decreased from 42% to 27% (P = 0.034).
T13 1515-1600 Sentence denotes Pain severity and analgesic requirements were unaffected by the omission of fentanyl.
T14 1601-1755 Sentence denotes Fentanyl did reduce minor intraoperative movement but had no sevoflurane-sparing effect and increased respiratory depression, hypotension and bradycardia.
T15 1756-1767 Sentence denotes CONCLUSION:
T16 1768-2017 Sentence denotes As fentanyl exacerbated postoperative nausea and vomiting without an improvement in postoperative pain and also had adverse cardiorespiratory effects, it appears to be an unnecessary and possibly detrimental supplement to sevoflurane in day surgery.