| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-62 |
Sentence |
denotes |
Anxiogenic potential of ciprofloxacin and norfloxacin in rats. |
| T2 |
63-76 |
Sentence |
denotes |
INTRODUCTION: |
| T3 |
77-256 |
Sentence |
denotes |
The possible anxiogenic effects of fluoroquinolones, namely ciprofloxacin and norfloxacin, were investigated in adult Charles Foster albino rats of either sex, weighing 150-200 g. |
| T4 |
257-265 |
Sentence |
denotes |
METHODS: |
| T5 |
266-394 |
Sentence |
denotes |
The drugs were given orally, in doses of 50 mg/kg for five consecutive days and the experiments were performed on the fifth day. |
| T6 |
395-559 |
Sentence |
denotes |
The tests included open-field exploratory behaviour, elevated plus maze and elevated zero maze, social interaction and novelty-suppressed feeding latency behaviour. |
| T7 |
560-568 |
Sentence |
denotes |
RESULTS: |
| T8 |
569-724 |
Sentence |
denotes |
The results indicate that ciprofloxacin- and norfloxacin-treated rats showed anxious behaviour in comparison to control rats in all the parameters studied. |
| T9 |
725-857 |
Sentence |
denotes |
However, ciprofloxacin- and norfloxacin-treated rats did not differ significantly from each other in various behavioural parameters. |
| T10 |
858-869 |
Sentence |
denotes |
CONCLUSION: |
| T11 |
870-995 |
Sentence |
denotes |
The present experimental findings substantiate the clinically observed anxiogenic potential of ciprofloxacin and norfloxacin. |
