Id |
Subject |
Object |
Predicate |
Lexical cue |
T1 |
0-72 |
Sentence |
denotes |
Polymorphic Alu insertions and the genetic structure of Iberian Basques. |
T2 |
73-232 |
Sentence |
denotes |
Eight Alu sequences (ACE, TPA25, PV92, APO, FXIIIB, D1, A25 and B65) were analyzed in two samples from Navarre and Guipúzcoa provinces (Basque Country, Spain). |
T3 |
233-442 |
Sentence |
denotes |
Alu data for other European, Caucasus and North African populations were compiled from the literature for comparison purposes to assess the genetic relationships of the Basques in a broader geographic context. |
T4 |
443-576 |
Sentence |
denotes |
Results of both MDS plot and AMOVA revealed spatial heterogeneity among these three population clusters clearly defined by geography. |
T5 |
577-741 |
Sentence |
denotes |
On the contrary, no substantial genetic heterogeneity was found between the Basque samples, or between Basques and other Europeans (excluding Caucasus populations). |
T6 |
742-938 |
Sentence |
denotes |
Moreover, the genetic information obtained from Alu data conflicts with hypotheses linking the origin of Basques with populations from North Africa (Berbers) or from the Caucasus region (Georgia). |
T7 |
939-1257 |
Sentence |
denotes |
In order to explain the reduced genetic heterogeneity detected by Alu insertions among Basque subpopulations, values of the Wright's F(ST )statistic were estimated for both Alu markers and a set of short tandem repeats (STRs) in terms of two geographical scales: (1) the Basque Country, (2) Europe (including Basques). |
T8 |
1258-1396 |
Sentence |
denotes |
In the Basque area, estimates of Wahlund's effect for both genetic markers showed no statistical difference between Basque subpopulations. |
T9 |
1397-1539 |
Sentence |
denotes |
However, when this analysis was performed on a European scale, F(ST) values were significantly higher for Alu insertions than for STR alleles. |
T10 |
1540-1863 |
Sentence |
denotes |
From these results, we suggest that the spatial heterogeneity of the Basque gene pool identified in previous polymorphism studies is relatively recent and probably caused by a differential process of genetic admixture with non-Basque neighboring populations modulated by the effect of a linguistic barrier to random mating. |