PubMed:17277899 JSONTXT 23 Projects

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Id Subject Object Predicate Lexical cue
T1 0-72 Sentence denotes Polymorphic Alu insertions and the genetic structure of Iberian Basques.
T2 73-232 Sentence denotes Eight Alu sequences (ACE, TPA25, PV92, APO, FXIIIB, D1, A25 and B65) were analyzed in two samples from Navarre and Guipúzcoa provinces (Basque Country, Spain).
T3 233-442 Sentence denotes Alu data for other European, Caucasus and North African populations were compiled from the literature for comparison purposes to assess the genetic relationships of the Basques in a broader geographic context.
T4 443-576 Sentence denotes Results of both MDS plot and AMOVA revealed spatial heterogeneity among these three population clusters clearly defined by geography.
T5 577-741 Sentence denotes On the contrary, no substantial genetic heterogeneity was found between the Basque samples, or between Basques and other Europeans (excluding Caucasus populations).
T6 742-938 Sentence denotes Moreover, the genetic information obtained from Alu data conflicts with hypotheses linking the origin of Basques with populations from North Africa (Berbers) or from the Caucasus region (Georgia).
T7 939-1257 Sentence denotes In order to explain the reduced genetic heterogeneity detected by Alu insertions among Basque subpopulations, values of the Wright's F(ST )statistic were estimated for both Alu markers and a set of short tandem repeats (STRs) in terms of two geographical scales: (1) the Basque Country, (2) Europe (including Basques).
T8 1258-1396 Sentence denotes In the Basque area, estimates of Wahlund's effect for both genetic markers showed no statistical difference between Basque subpopulations.
T9 1397-1539 Sentence denotes However, when this analysis was performed on a European scale, F(ST) values were significantly higher for Alu insertions than for STR alleles.
T10 1540-1863 Sentence denotes From these results, we suggest that the spatial heterogeneity of the Basque gene pool identified in previous polymorphism studies is relatively recent and probably caused by a differential process of genetic admixture with non-Basque neighboring populations modulated by the effect of a linguistic barrier to random mating.