Id |
Subject |
Object |
Predicate |
Lexical cue |
T1 |
0-140 |
Sentence |
denotes |
People aged over 75 in atrial fibrillation on warfarin: the rate of major hemorrhage and stroke in more than 500 patient-years of follow-up. |
T2 |
141-152 |
Sentence |
denotes |
OBJECTIVES: |
T3 |
153-338 |
Sentence |
denotes |
To determine the incidence of major hemorrhage and stroke in people aged 76 and older with atrial fibrillation on adjusted-dose warfarin who had been recently been admitted to hospital. |
T4 |
339-346 |
Sentence |
denotes |
DESIGN: |
T5 |
347-390 |
Sentence |
denotes |
A retrospective observational cohort study. |
T6 |
391-399 |
Sentence |
denotes |
SETTING: |
T7 |
400-461 |
Sentence |
denotes |
A major healthcare network involving four tertiary hospitals. |
T8 |
462-475 |
Sentence |
denotes |
PARTICIPANTS: |
T9 |
476-658 |
Sentence |
denotes |
Two hundred thirty-five patients aged 76 and older admitted to a major healthcare network between July 1, 2001, and June 30, 2002, with atrial fibrillation on warfarin were enrolled. |
T10 |
659-672 |
Sentence |
denotes |
MEASUREMENTS: |
T11 |
673-825 |
Sentence |
denotes |
Information regarding major bleeding episodes, strokes, and warfarin use was obtained from patients, relatives, primary physicians, and medical records. |
T12 |
826-834 |
Sentence |
denotes |
RESULTS: |
T13 |
835-947 |
Sentence |
denotes |
Two hundred twenty-eight patients (42% men) with a mean age of 81.1 (range 76-94) were included in the analysis. |
T14 |
948-1007 |
Sentence |
denotes |
Total follow-up on warfarin was 530 years (mean 28 months). |
T15 |
1008-1137 |
Sentence |
denotes |
There were 53 major hemorrhages, for an annual rate of 10.0%, including 24 (45.3%) life-threatening and five (9.4%) fatal bleeds. |
T16 |
1138-1199 |
Sentence |
denotes |
The annual stroke rate after initiation of warfarin was 2.6%. |
T17 |
1200-1211 |
Sentence |
denotes |
CONCLUSION: |
T18 |
1212-1428 |
Sentence |
denotes |
The rate of major hemorrhage was high in this old, frail group, but excluding fatalities, resulted in no long-term sequelae, and the stroke rate on warfarin was low, demonstrating how effective warfarin treatment is. |