PubMed:15817013 JSONTXT 23 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 0-140 Sentence denotes People aged over 75 in atrial fibrillation on warfarin: the rate of major hemorrhage and stroke in more than 500 patient-years of follow-up.
T2 141-152 Sentence denotes OBJECTIVES:
T3 153-338 Sentence denotes To determine the incidence of major hemorrhage and stroke in people aged 76 and older with atrial fibrillation on adjusted-dose warfarin who had been recently been admitted to hospital.
T4 339-346 Sentence denotes DESIGN:
T5 347-390 Sentence denotes A retrospective observational cohort study.
T6 391-399 Sentence denotes SETTING:
T7 400-461 Sentence denotes A major healthcare network involving four tertiary hospitals.
T8 462-475 Sentence denotes PARTICIPANTS:
T9 476-658 Sentence denotes Two hundred thirty-five patients aged 76 and older admitted to a major healthcare network between July 1, 2001, and June 30, 2002, with atrial fibrillation on warfarin were enrolled.
T10 659-672 Sentence denotes MEASUREMENTS:
T11 673-825 Sentence denotes Information regarding major bleeding episodes, strokes, and warfarin use was obtained from patients, relatives, primary physicians, and medical records.
T12 826-834 Sentence denotes RESULTS:
T13 835-947 Sentence denotes Two hundred twenty-eight patients (42% men) with a mean age of 81.1 (range 76-94) were included in the analysis.
T14 948-1007 Sentence denotes Total follow-up on warfarin was 530 years (mean 28 months).
T15 1008-1137 Sentence denotes There were 53 major hemorrhages, for an annual rate of 10.0%, including 24 (45.3%) life-threatening and five (9.4%) fatal bleeds.
T16 1138-1199 Sentence denotes The annual stroke rate after initiation of warfarin was 2.6%.
T17 1200-1211 Sentence denotes CONCLUSION:
T18 1212-1428 Sentence denotes The rate of major hemorrhage was high in this old, frail group, but excluding fatalities, resulted in no long-term sequelae, and the stroke rate on warfarin was low, demonstrating how effective warfarin treatment is.