| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-54 |
Sentence |
denotes |
Pheochromocytoma unmasked by amisulpride and tiapride. |
| T2 |
55-65 |
Sentence |
denotes |
OBJECTIVE: |
| T3 |
66-163 |
Sentence |
denotes |
To describe the unmasking of pheochromocytoma in a patient treated with amisulpride and tiapride. |
| T4 |
164-177 |
Sentence |
denotes |
CASE SUMMARY: |
| T5 |
178-337 |
Sentence |
denotes |
A 42-year-old white man developed acute hypertension with severe headache and vomiting 2 hours after the first doses of amisulpride 100 mg and tiapride 100 mg. |
| T6 |
338-459 |
Sentence |
denotes |
Both drugs were immediately discontinued, and the patient recovered after subsequent nicardipine and verapamil treatment. |
| T7 |
460-590 |
Sentence |
denotes |
Abdominal ultrasound showed an adrenal mass, and postoperative histologic examination confirmed the diagnosis of pheochromocytoma. |
| T8 |
591-602 |
Sentence |
denotes |
DISCUSSION: |
| T9 |
603-751 |
Sentence |
denotes |
Drug-induced symptoms of pheochromocytoma are often associated with the use of substituted benzamide drugs, but the underlying mechanism is unknown. |
| T10 |
752-905 |
Sentence |
denotes |
In our case, use of the Naranjo probability scale indicated a possible relationship between the hypertensive crisis and amisulpride and tiapride therapy. |
| T11 |
906-918 |
Sentence |
denotes |
CONCLUSIONS: |
| T12 |
919-1065 |
Sentence |
denotes |
As of March 24, 2005, this is the first reported case of amisulpride- and tiapride-induced hypertensive crisis in a patient with pheochromocytoma. |
| T13 |
1066-1189 |
Sentence |
denotes |
Physicians and other healthcare professionals should be aware of this potential adverse effect of tiapride and amisulpride. |