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PubMed:9888865 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-85 Sentence denotes Tissue factor expression of human monocytes is suppressed by lysophosphatidylcholine.
T1 0-85 Sentence denotes Tissue factor expression of human monocytes is suppressed by lysophosphatidylcholine.
T2 86-217 Sentence denotes The expression of tissue factor (TF), the principal initiator of coagulation, is increased during inflammation and atherosclerosis.
T2 86-217 Sentence denotes The expression of tissue factor (TF), the principal initiator of coagulation, is increased during inflammation and atherosclerosis.
T3 218-283 Sentence denotes Both conditions are promoted by lysophosphatidylcholine (lysoPC).
T3 218-283 Sentence denotes Both conditions are promoted by lysophosphatidylcholine (lysoPC).
T4 284-447 Sentence denotes We observed in the present study that lysoPC (1 to 10 micromol/L) dose-dependently reduced TF activity in human monocytes, as elicited by lipopolysaccharide (LPS).
T4 284-447 Sentence denotes We observed in the present study that lysoPC (1 to 10 micromol/L) dose-dependently reduced TF activity in human monocytes, as elicited by lipopolysaccharide (LPS).
T5 448-572 Sentence denotes Lysophosphatidylethanolamine (lysoPE) and other lysophospholipids did not affect LPS-induced TF activity of human monocytes.
T5 448-572 Sentence denotes Lysophosphatidylethanolamine (lysoPE) and other lysophospholipids did not affect LPS-induced TF activity of human monocytes.
T6 573-641 Sentence denotes TF antigen expression as elicited by LPS was also lowered by lysoPC.
T6 573-641 Sentence denotes TF antigen expression as elicited by LPS was also lowered by lysoPC.
T7 642-780 Sentence denotes Phospholipid analyses indicated a selective increase in the lysoPC content of the monocytes after preincubation with the lysophospholipid.
T7 642-780 Sentence denotes Phospholipid analyses indicated a selective increase in the lysoPC content of the monocytes after preincubation with the lysophospholipid.
T8 781-874 Sentence denotes LysoPC inhibited the TF activity of Mono Mac-6 cells to a similar extent as in the monocytes.
T8 781-874 Sentence denotes LysoPC inhibited the TF activity of Mono Mac-6 cells to a similar extent as in the monocytes.
T9 875-986 Sentence denotes LPS binding to plasma membrane receptors and internalization of LPS into monocytes were not affected by lysoPC.
T9 875-986 Sentence denotes LPS binding to plasma membrane receptors and internalization of LPS into monocytes were not affected by lysoPC.
T10 987-1111 Sentence denotes In contrast, LPS-mediated nuclear binding of nuclear factor-kappaB/Rel to a TF-specific kappaB site was inhibited by lysoPC.
T10 987-1111 Sentence denotes In contrast, LPS-mediated nuclear binding of nuclear factor-kappaB/Rel to a TF-specific kappaB site was inhibited by lysoPC.
T11 1112-1206 Sentence denotes Induction of TF mRNA expression by LPS tended to be partially reduced by the lysophospholipid.
T11 1112-1206 Sentence denotes Induction of TF mRNA expression by LPS tended to be partially reduced by the lysophospholipid.
T12 1207-1265 Sentence denotes Preincubation with lysoPC increased monocytic cAMP levels.
T12 1207-1265 Sentence denotes Preincubation with lysoPC increased monocytic cAMP levels.
T13 1266-1422 Sentence denotes Inhibition of adenylyl cyclase by pretreatment with 2'-deoxy-3'-adenosine monophosphate partially reversed the inhibition of TF activity promoted by lysoPC.
T13 1266-1422 Sentence denotes Inhibition of adenylyl cyclase by pretreatment with 2'-deoxy-3'-adenosine monophosphate partially reversed the inhibition of TF activity promoted by lysoPC.
T14 1423-1605 Sentence denotes In conclusion, lysoPC markedly decreases LPS-mediated TF expression of human monocytes, the effect probably being mediated by both transcriptional and posttranscriptional mechanisms.
T14 1423-1605 Sentence denotes In conclusion, lysoPC markedly decreases LPS-mediated TF expression of human monocytes, the effect probably being mediated by both transcriptional and posttranscriptional mechanisms.
T15 1606-1698 Sentence denotes LysoPC may thus attenuate activation of coagulation during inflammation and atherosclerosis.
T15 1606-1698 Sentence denotes LysoPC may thus attenuate activation of coagulation during inflammation and atherosclerosis.