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PubMed:9802632 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-101 Sentence denotes Inflammatory mediators in Escherichia coli O157:H7 hemorrhagic colitis and hemolytic-uremic syndrome.
T1 0-101 Sentence denotes Inflammatory mediators in Escherichia coli O157:H7 hemorrhagic colitis and hemolytic-uremic syndrome.
T2 102-113 Sentence denotes BACKGROUND:
T2 102-113 Sentence denotes BACKGROUND:
T3 114-334 Sentence denotes Recent experimental data suggest that the inflammatory response of the host to verotoxin and/or lipopolysaccharides of Escherichia coli is involved in the pathophysiology of verotoxin-producing E. coli (VTEC) infections.
T3 114-334 Sentence denotes Recent experimental data suggest that the inflammatory response of the host to verotoxin and/or lipopolysaccharides of Escherichia coli is involved in the pathophysiology of verotoxin-producing E. coli (VTEC) infections.
T4 335-343 Sentence denotes METHODS:
T4 335-343 Sentence denotes METHODS:
T5 344-953 Sentence denotes We measured the circulating concentrations of cytokines [TNF-alpha, interleukin (IL)-1-beta, IL-1 receptor antagonist (Ra), IL-6, IL-8, IL-10] and soluble leukocyte adhesion molecules (L-selectin, P-selectin, E-selectin, intracellular cell adhesion molecule-1, vascular cell adhesion molecule-1) by sandwich enzyme-linked immunosorbent assay among (1) normal controls (n = 12), (2) disease controls with hemorrhagic colitis (HC) not associated with VTEC infections (n = 57), (3) patients with uncomplicated HC caused by E. coli O157:H7 (n = 30), and (4) children with hemolytic-uremic syndrome (HUS) (n = 28).
T5 344-953 Sentence denotes We measured the circulating concentrations of cytokines [TNF-alpha, interleukin (IL)-1-beta, IL-1 receptor antagonist (Ra), IL-6, IL-8, IL-10] and soluble leukocyte adhesion molecules (L-selectin, P-selectin, E-selectin, intracellular cell adhesion molecule-1, vascular cell adhesion molecule-1) by sandwich enzyme-linked immunosorbent assay among (1) normal controls (n = 12), (2) disease controls with hemorrhagic colitis (HC) not associated with VTEC infections (n = 57), (3) patients with uncomplicated HC caused by E. coli O157:H7 (n = 30), and (4) children with hemolytic-uremic syndrome (HUS) (n = 28).
T6 954-1149 Sentence denotes Patients with HUS were matched with children who presented an uncomplicated HC caused by E. coli O157:H7 for the time interval elapsed between the onset of HC and that of blood sample collection.
T6 954-1149 Sentence denotes Patients with HUS were matched with children who presented an uncomplicated HC caused by E. coli O157:H7 for the time interval elapsed between the onset of HC and that of blood sample collection.
T7 1150-1158 Sentence denotes RESULTS:
T7 1150-1158 Sentence denotes RESULTS:
T8 1159-1219 Sentence denotes Concentrations of TNF-alpha and IL-1-beta were undetectable.
T8 1159-1219 Sentence denotes Concentrations of TNF-alpha and IL-1-beta were undetectable.
T9 1220-1379 Sentence denotes Children with HUS were characterized by increased amounts of IL-6 and IL-8, lower values of soluble L-selectin as well as increased levels of IL-10 and IL-1Ra.
T9 1220-1379 Sentence denotes Children with HUS were characterized by increased amounts of IL-6 and IL-8, lower values of soluble L-selectin as well as increased levels of IL-10 and IL-1Ra.
T10 1380-1495 Sentence denotes The circulating concentrations of IL-1Ra were higher among children with O157:H7 HC who subsequently developed HUS.
T10 1380-1495 Sentence denotes The circulating concentrations of IL-1Ra were higher among children with O157:H7 HC who subsequently developed HUS.
T11 1496-1508 Sentence denotes CONCLUSIONS:
T11 1496-1508 Sentence denotes CONCLUSIONS:
T12 1509-1655 Sentence denotes Increased pro- and antiinflammatory cytokine responses are produced by the host during the development of HUS among children with VTEC infections.
T12 1509-1655 Sentence denotes Increased pro- and antiinflammatory cytokine responses are produced by the host during the development of HUS among children with VTEC infections.
T13 1656-1762 Sentence denotes Further studies are needed to determine their relative contribution to the pathophysiology of classic HUS.
T13 1656-1762 Sentence denotes Further studies are needed to determine their relative contribution to the pathophysiology of classic HUS.