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Id Subject Object Predicate Lexical cue
T1 0-135 Sentence denotes Effect of treatment with paromomycin on endotoxemia in patients with alcoholic liver disease--a double-blind, placebo-controlled trial.
T1 0-135 Sentence denotes Effect of treatment with paromomycin on endotoxemia in patients with alcoholic liver disease--a double-blind, placebo-controlled trial.
T2 136-316 Sentence denotes The results of experimental and clinical studies support the hypothesis that gut-derived endotoxins might be of relevance for the development and course of alcoholic liver disease.
T2 136-316 Sentence denotes The results of experimental and clinical studies support the hypothesis that gut-derived endotoxins might be of relevance for the development and course of alcoholic liver disease.
T3 317-464 Sentence denotes The aim of this study was to test the effect of a nonabsorbable, broad-spectrum antibiotic on endotoxemia in patients with alcoholic liver disease.
T3 317-464 Sentence denotes The aim of this study was to test the effect of a nonabsorbable, broad-spectrum antibiotic on endotoxemia in patients with alcoholic liver disease.
T4 465-709 Sentence denotes Fifty patients with alcoholic liver disease (27 with cirrhosis, 23 without cirrhosis) were randomly assigned to receive either paromomycin sulfate (3 x 1 g/day) or placebo in a double-blind fashion for at least 3 weeks, and if possible 4 weeks.
T4 465-709 Sentence denotes Fifty patients with alcoholic liver disease (27 with cirrhosis, 23 without cirrhosis) were randomly assigned to receive either paromomycin sulfate (3 x 1 g/day) or placebo in a double-blind fashion for at least 3 weeks, and if possible 4 weeks.
T5 710-825 Sentence denotes Endotoxin concentration, liver function tests, and other laboratory parameters were determined in weekly intervals.
T5 710-825 Sentence denotes Endotoxin concentration, liver function tests, and other laboratory parameters were determined in weekly intervals.
T6 826-893 Sentence denotes Endotoxin concentration was also determined in 15 healthy controls.
T6 826-893 Sentence denotes Endotoxin concentration was also determined in 15 healthy controls.
T7 894-1001 Sentence denotes Groups receiving paromomycin or placebo were similar for clinical and biological items collected initially.
T7 894-1001 Sentence denotes Groups receiving paromomycin or placebo were similar for clinical and biological items collected initially.
T8 1002-1197 Sentence denotes Mean initial endotoxin concentrations were significantly elevated in both groups (mean +/- SEM; paromomycin, 16.7 +/- 5.3 pg/ml; placebo, 17.5 +/- 6.9 pg/ml; healthy controls, 2.3 +/- 0.4 pg/ml).
T8 1002-1197 Sentence denotes Mean initial endotoxin concentrations were significantly elevated in both groups (mean +/- SEM; paromomycin, 16.7 +/- 5.3 pg/ml; placebo, 17.5 +/- 6.9 pg/ml; healthy controls, 2.3 +/- 0.4 pg/ml).
T9 1198-1479 Sentence denotes Although the mean endotoxin concentration was lower in the verum group after 1 week (paromomycin, 8.0 +/- 1.9 pg/ml; placebo, 14.6 +/- 3.5 pg/ml; p > 0.05), paromomycin treatment had no significant effect on endotoxin concentration or liver function tests during the 4-week period.
T9 1198-1479 Sentence denotes Although the mean endotoxin concentration was lower in the verum group after 1 week (paromomycin, 8.0 +/- 1.9 pg/ml; placebo, 14.6 +/- 3.5 pg/ml; p > 0.05), paromomycin treatment had no significant effect on endotoxin concentration or liver function tests during the 4-week period.
T10 1480-1684 Sentence denotes The beneficial effect of paromomycin treatment on endotoxemia in cirrhotics reported in earlier studies could not be reproduced under the conditions of this trial in patients with alcoholic liver disease.
T10 1480-1684 Sentence denotes The beneficial effect of paromomycin treatment on endotoxemia in cirrhotics reported in earlier studies could not be reproduced under the conditions of this trial in patients with alcoholic liver disease.