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PubMed:9095577 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-76 Sentence denotes Oxidant-regulation of gene expression in the chronically inflamed intestine.
T1 0-76 Sentence denotes Oxidant-regulation of gene expression in the chronically inflamed intestine.
T2 77-315 Sentence denotes It is becoming increasingly apparent that the chronic gut inflammation observed in the idiopathic inflammatory bowel diseases (e.g. ulcerative colitis, Crohn's disease) is associated with enhanced production of leukocyte-derived oxidants.
T2 77-315 Sentence denotes It is becoming increasingly apparent that the chronic gut inflammation observed in the idiopathic inflammatory bowel diseases (e.g. ulcerative colitis, Crohn's disease) is associated with enhanced production of leukocyte-derived oxidants.
T3 316-451 Sentence denotes Oxidants such as hydrogen peroxide are known to activate certain transcription factors such as nuclear transcription factor kappa beta.
T3 316-451 Sentence denotes Oxidants such as hydrogen peroxide are known to activate certain transcription factors such as nuclear transcription factor kappa beta.
T4 452-628 Sentence denotes Nuclear transcription factor kB (NF-kappa B) is a ubiquitous transcription factor and pleiotropic regulator of numerous genes involved in the immune and inflammatory responses.
T4 452-628 Sentence denotes Nuclear transcription factor kB (NF-kappa B) is a ubiquitous transcription factor and pleiotropic regulator of numerous genes involved in the immune and inflammatory responses.
T5 629-968 Sentence denotes This transcription factor is activated via the selective phosphorylation, ubiquination and degradation of its inhibitor protein I-kB thereby allowing translocation of NF-kappa B into the nucleus where it upregulates the transcription of a variety of adhesion molecules (e.g. ICAM-1, VCAM-1), cytokines (TNF, IL-1, IL-6) and enzymes (iNOS).
T5 629-968 Sentence denotes This transcription factor is activated via the selective phosphorylation, ubiquination and degradation of its inhibitor protein I-kB thereby allowing translocation of NF-kappa B into the nucleus where it upregulates the transcription of a variety of adhesion molecules (e.g. ICAM-1, VCAM-1), cytokines (TNF, IL-1, IL-6) and enzymes (iNOS).
T6 969-1098 Sentence denotes The proteolytic degradation of the post-translationally modified I-kappa B is known to be mediated by the 26S proteasome complex.
T6 969-1098 Sentence denotes The proteolytic degradation of the post-translationally modified I-kappa B is known to be mediated by the 26S proteasome complex.
T7 1099-1354 Sentence denotes Based upon work from our laboratory, we propose that inhibition of NF-kappa B activation produces significant anti inflammatory activity which may be mediated by the inhibition of transcription of certain pro-inflammatory mediators and adhesion molecules.
T7 1099-1354 Sentence denotes Based upon work from our laboratory, we propose that inhibition of NF-kappa B activation produces significant anti inflammatory activity which may be mediated by the inhibition of transcription of certain pro-inflammatory mediators and adhesion molecules.