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PubMed:9069290 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-83 Sentence denotes Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation.
T1 0-83 Sentence denotes Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation.
T2 84-304 Sentence denotes For cells of the innate immune system to mount a host defence response to infection, they must recognize products of microbial pathogens such as lipopolysaccharide (LPS), the endotoxin secreted by Gram-negative bacteria.
T2 84-304 Sentence denotes For cells of the innate immune system to mount a host defence response to infection, they must recognize products of microbial pathogens such as lipopolysaccharide (LPS), the endotoxin secreted by Gram-negative bacteria.
T3 305-417 Sentence denotes These cellular responses require intracellular signalling pathways, such as the four MAP kinase (MAPK) pathways.
T3 305-417 Sentence denotes These cellular responses require intracellular signalling pathways, such as the four MAP kinase (MAPK) pathways.
T4 418-611 Sentence denotes In mammalian cells the MAPK p38 is thought to play an important role in the regulation of cellular responses during infection through its effects on the expression of proinflammatory molecules.
T4 418-611 Sentence denotes In mammalian cells the MAPK p38 is thought to play an important role in the regulation of cellular responses during infection through its effects on the expression of proinflammatory molecules.
T5 612-756 Sentence denotes One means of understanding the role of p38 in these responses is to identify proteins with functions regulated by p38-catalysed phosphorylation.
T5 612-756 Sentence denotes One means of understanding the role of p38 in these responses is to identify proteins with functions regulated by p38-catalysed phosphorylation.
T6 757-892 Sentence denotes Here we demonstrate a link between the p38 pathway and a member of the myocyte-enhancer factor 2 (MEF2) group of transcription factors.
T6 757-892 Sentence denotes Here we demonstrate a link between the p38 pathway and a member of the myocyte-enhancer factor 2 (MEF2) group of transcription factors.
T7 893-1017 Sentence denotes We found that in monocytic cells, LPS increases the transactivation activity of MEF2C through p38-catalysed phosphorylation.
T7 893-1017 Sentence denotes We found that in monocytic cells, LPS increases the transactivation activity of MEF2C through p38-catalysed phosphorylation.
T8 1018-1092 Sentence denotes One consequence of MEF2C activation is increased c-jun gene transcription.
T8 1018-1092 Sentence denotes One consequence of MEF2C activation is increased c-jun gene transcription.
T9 1093-1233 Sentence denotes Our results show that p38 may influence host defence and inflammation by maintaining the balance of c-Jun protein consumed during infection.
T9 1093-1233 Sentence denotes Our results show that p38 may influence host defence and inflammation by maintaining the balance of c-Jun protein consumed during infection.