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PubMed:8816424 JSONTXT 14 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-57 Sentence denotes Regulation of sialoadhesin expression on rat macrophages.
T1 0-57 Sentence denotes Regulation of sialoadhesin expression on rat macrophages.
T2 58-156 Sentence denotes Induction by glucocorticoids and enhancement by IFN-beta, IFN-gamma, IL-4, and lipopolysaccharide.
T2 58-156 Sentence denotes Induction by glucocorticoids and enhancement by IFN-beta, IFN-gamma, IL-4, and lipopolysaccharide.
T3 157-281 Sentence denotes Sialoadhesin is a macrophage-restricted member of the Ig superfamily that mediates adhesion with lymphoid and myeloid cells.
T3 157-281 Sentence denotes Sialoadhesin is a macrophage-restricted member of the Ig superfamily that mediates adhesion with lymphoid and myeloid cells.
T4 282-415 Sentence denotes It is expressed on a subpopulation of macrophages in lymphoid tissues and in chronic inflammation (e.g., during autoimmune diseases).
T4 282-415 Sentence denotes It is expressed on a subpopulation of macrophages in lymphoid tissues and in chronic inflammation (e.g., during autoimmune diseases).
T5 416-621 Sentence denotes We have studied the regulation of sialoadhesin expression in vitro and show that glucocorticoids (GC) induce sialoadhesin expression on freshly isolated rat macrophages and the rat macrophage cell line R2.
T5 416-621 Sentence denotes We have studied the regulation of sialoadhesin expression in vitro and show that glucocorticoids (GC) induce sialoadhesin expression on freshly isolated rat macrophages and the rat macrophage cell line R2.
T6 622-796 Sentence denotes The cytokines IFN-beta, IFN-gamma, IL-4, and LPS, although unable to induce sialoadhesin expression by themselves, were able to enhance GC-mediated induction of sialoadhesin.
T6 622-796 Sentence denotes The cytokines IFN-beta, IFN-gamma, IL-4, and LPS, although unable to induce sialoadhesin expression by themselves, were able to enhance GC-mediated induction of sialoadhesin.
T7 797-885 Sentence denotes Sialoadhesin expression was functional as shown by cell adhesion assays with human RBCs.
T7 797-885 Sentence denotes Sialoadhesin expression was functional as shown by cell adhesion assays with human RBCs.
T8 886-983 Sentence denotes Northern blotting experiments indicated that regulation predominantly occurred at the mRNA level.
T8 886-983 Sentence denotes Northern blotting experiments indicated that regulation predominantly occurred at the mRNA level.
T9 984-1203 Sentence denotes Comparison of the different combinations of GC and cytokines/LPS revealed differences in the level of GC-dependent enhancement of sialoadhesin expression, with IFN-beta and IL-4 being more potent than IFN-gamma and LPS.
T9 984-1203 Sentence denotes Comparison of the different combinations of GC and cytokines/LPS revealed differences in the level of GC-dependent enhancement of sialoadhesin expression, with IFN-beta and IL-4 being more potent than IFN-gamma and LPS.
T10 1204-1342 Sentence denotes Moreover, the effects of IFN-gamma and LPS could be reproduced by priming, whereas IFN-beta and IL-4 were required simultaneously with GC.
T10 1204-1342 Sentence denotes Moreover, the effects of IFN-gamma and LPS could be reproduced by priming, whereas IFN-beta and IL-4 were required simultaneously with GC.
T11 1343-1518 Sentence denotes The regulation of sialoadhesin expression was mediated by the GC receptor, and not by mineralocorticoid receptor, as shown by inhibition experiments with specific antagonists.
T11 1343-1518 Sentence denotes The regulation of sialoadhesin expression was mediated by the GC receptor, and not by mineralocorticoid receptor, as shown by inhibition experiments with specific antagonists.
T12 1519-1651 Sentence denotes Finally, it is demonstrated that macrophages in the adrenal gland, the major site of endogenous GC production, express sialoadhesin.
T12 1519-1651 Sentence denotes Finally, it is demonstrated that macrophages in the adrenal gland, the major site of endogenous GC production, express sialoadhesin.
T13 1652-1840 Sentence denotes This study demonstrates that GC act as a primary inducer of sialoadhesin expression on rat macrophages, and that the response can be enhanced by IFN-beta, T cell-derived cytokines, or LPS.
T13 1652-1840 Sentence denotes This study demonstrates that GC act as a primary inducer of sialoadhesin expression on rat macrophages, and that the response can be enhanced by IFN-beta, T cell-derived cytokines, or LPS.