| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-83 |
Sentence |
denotes |
Involvement of tyrosine phosphorylation in endothelial adhesion molecule induction. |
| T1 |
0-83 |
Sentence |
denotes |
Involvement of tyrosine phosphorylation in endothelial adhesion molecule induction. |
| T2 |
84-412 |
Sentence |
denotes |
Induction of endothelial adhesion molecules by the cytokine tumor necrosis factor-alpha (TNF) can occur independently of protein kinase C and activation of a protein tyrosine kinase (PTK) has recently been implicated in the upregulation of vascular cell adhesion molecule 1 (VCAM-1) by interleukin-4 (IL-4) on endothelial cells. |
| T2 |
84-412 |
Sentence |
denotes |
Induction of endothelial adhesion molecules by the cytokine tumor necrosis factor-alpha (TNF) can occur independently of protein kinase C and activation of a protein tyrosine kinase (PTK) has recently been implicated in the upregulation of vascular cell adhesion molecule 1 (VCAM-1) by interleukin-4 (IL-4) on endothelial cells. |
| T3 |
413-620 |
Sentence |
denotes |
We demonstrate that the PTK inhibitors herbimycin A or genistein suppress induction of endothelial VCAM-1 and E-selectin, as well as subsequent monocytic cell adhesion to endothelial cells stimulated by TNF. |
| T3 |
413-620 |
Sentence |
denotes |
We demonstrate that the PTK inhibitors herbimycin A or genistein suppress induction of endothelial VCAM-1 and E-selectin, as well as subsequent monocytic cell adhesion to endothelial cells stimulated by TNF. |
| T4 |
621-825 |
Sentence |
denotes |
Inhibition studies indicate that specific tyrosine phosphorylation following PTK activation is involved in the mobilization of the transcription factor, nuclear factor kappa B, and VCAM-1 mRNA expression. |
| T4 |
621-825 |
Sentence |
denotes |
Inhibition studies indicate that specific tyrosine phosphorylation following PTK activation is involved in the mobilization of the transcription factor, nuclear factor kappa B, and VCAM-1 mRNA expression. |
| T5 |
826-976 |
Sentence |
denotes |
This may have implications for pathophysiological conditions that involve the upregulation of these molecules (e.g. inflammation and atherosclerosis). |
| T5 |
826-976 |
Sentence |
denotes |
This may have implications for pathophysiological conditions that involve the upregulation of these molecules (e.g. inflammation and atherosclerosis). |