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PubMed:8666816 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-107 Sentence denotes Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes.
T1 0-107 Sentence denotes Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes.
T2 108-248 Sentence denotes Eosinophils and neutrophils are closely related, terminally differentiated cells that in vitro undergo constitutive cell death by apoptosis.
T2 108-248 Sentence denotes Eosinophils and neutrophils are closely related, terminally differentiated cells that in vitro undergo constitutive cell death by apoptosis.
T3 249-349 Sentence denotes The onset of apoptosis in both cell types can be delayed by hemopoietins and inflammatory mediators.
T3 249-349 Sentence denotes The onset of apoptosis in both cell types can be delayed by hemopoietins and inflammatory mediators.
T4 350-608 Sentence denotes Although there have been a number of reports demonstrating that glucocorticoids (in particular dexamethasone) antagonize the eosinophil life-prolonging effects of hemopoietins, direct effects of dexamethasone on eosinophil apoptosis have not been documented.
T4 350-608 Sentence denotes Although there have been a number of reports demonstrating that glucocorticoids (in particular dexamethasone) antagonize the eosinophil life-prolonging effects of hemopoietins, direct effects of dexamethasone on eosinophil apoptosis have not been documented.
T5 609-817 Sentence denotes In this study we examined the direct effects of glucocorticoids on eosinophil and neutrophil apoptosis in light of their common therapeutic use as anti-inflammatory and anti-allergic/hypereosinophilic agents.
T5 609-817 Sentence denotes In this study we examined the direct effects of glucocorticoids on eosinophil and neutrophil apoptosis in light of their common therapeutic use as anti-inflammatory and anti-allergic/hypereosinophilic agents.
T6 818-890 Sentence denotes We found that treatment with dexamethasone induced eosinophil apoptosis.
T6 818-890 Sentence denotes We found that treatment with dexamethasone induced eosinophil apoptosis.
T7 891-965 Sentence denotes In contrast, dexamethasone was a potent inhibitor of neutrophil apoptosis.
T7 891-965 Sentence denotes In contrast, dexamethasone was a potent inhibitor of neutrophil apoptosis.
T8 966-1136 Sentence denotes The effect of dexamethasone on both cell types was mediated through the glucocorticoid receptor, i.e., it was abolished by the glucocorticoid receptor antagonist RU38486.
T8 966-1136 Sentence denotes The effect of dexamethasone on both cell types was mediated through the glucocorticoid receptor, i.e., it was abolished by the glucocorticoid receptor antagonist RU38486.
T9 1137-1458 Sentence denotes This is the first description of an agent that promotes eosinophil apoptosis while inhibiting neutrophil apoptosis, and thus presents a novel approach to the study of control of apoptosis in these closely related cell types as well as increases our understanding of the clinical action of glucocorticoids in inflammation.
T9 1137-1458 Sentence denotes This is the first description of an agent that promotes eosinophil apoptosis while inhibiting neutrophil apoptosis, and thus presents a novel approach to the study of control of apoptosis in these closely related cell types as well as increases our understanding of the clinical action of glucocorticoids in inflammation.